Oromucosal midazolam: a review of its use in pediatric patients with prolonged acute convulsive seizures [0.03%]
口服和黏膜给药的咪达唑仑在治疗儿童持续性急性惊厥中的应用综述
Karly P Garnock-Jones
Karly P Garnock-Jones
Oromucosal midazolam (Buccolam™) is a benzodiazepine approved for the treatment of pediatric patients with acute, prolonged, convulsive seizures. This article reviews the pharmacologic properties of oromucosal midazolam and its clinical ef...
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants [0.03%]
新生儿和婴儿利尿剂呋塞米和布美他尼的临床药理学
Gian Maria Pacifici
Gian Maria Pacifici
The loop diuretics furosemide and bumetanide are used widely for the management of fluid overload in both acute and chronic disease states. To date, most pharmacokinetic studies in neonates have been conducted with furosemide and little is ...
Current and future management strategies for relapsed or progressive hepatoblastoma [0.03%]
复发性或进行性肝母细胞瘤的当前和未来的管理策略
Rajkumar Venkatramani,Wayne L Furman,Joerg Fuchs et al.
Rajkumar Venkatramani et al.
Hepatoblastoma is the most common primary malignant neoplasm of the liver in children. Improvements in chemotherapy and surgical techniques have increased survival rates for those with localized disease. The prognosis for patients with prog...
Glycopyrrolate oral solution: for chronic, severe drooling in pediatric patients with neurologic conditions [0.03%]
甘羟铝口服溶液：用于神经学疾病儿童患者的慢性严重流涎症
Karly P Garnock-Jones
Karly P Garnock-Jones
Chronic drooling (sialorrhea) is a common dysfunction in children with neurologic disorders such as cerebral palsy. Glycopyrrolate oral solution, an anticholinergic agent, is the first drug treatment approved in the US for drooling in child...
Sandra Chuang,Adam Jaffe
Sandra Chuang
Asthma is a prevalent health condition in children, with economic implications for the individual and their family, as well as for societies with nationalized healthcare. Pharmaceutical cost is the main driver of healthcare expenditure in a...
Shinya Ito,Hidefumi Nakamura,Tohru Kobayashi
Shinya Ito
Olmesartan medoxomil in children and adolescents with hypertension†: profile report [0.03%]
奥美沙坦酯治疗高血压儿童和青少年的临床特征分析报告
Victoria J Muir,Gillian M Keating
Victoria J Muir
†Adapted and reproduced from the original article published in Drugs 2010; 70 (18): 2439-47.
E Ann Yeh
E Ann Yeh
Pediatric onset multiple sclerosis (MS) may be seen in 2-5% of patients with MS. It is characterized by high disease burden. As such, early treatment with preventative therapies should be considered. Although randomized controlled trials ha...
Current management of juvenile myelomonocytic leukemia and the impact of RAS mutations [0.03%]
JMML当前的治疗及RAS突变的影响
Nao Yoshida,Sayoko Doisaki,Seiji Kojima
Nao Yoshida
Juvenile myelomonocytic leukemia (JMML) is a rare clonal myelodysplastic/myeloproliferative disorder that affects young children. It is characterized by hypersensitivity of JMML cells to granulocyte-macrophage colony-stimulating factor (GM-...
Victor Uko,Kadakkal Radhakrishnan,Naim Alkhouri
Victor Uko
Short bowel syndrome (SBS) reflects a state of malabsorption that occurs due to loss of a significant portion of the small bowel. The pathophysiology of SBS is determined largely by the process of adaptation, which is the innate attempt by ...