Pharmacotherapeutic management of pediatric gliomas : current and upcoming strategies [0.03%]
儿童胶质瘤的药理治疗管理：目前和即将推出的策略
Trent R Hummel,Lionel M Chow,Maryam Fouladi et al.
Trent R Hummel et al.
Primary glial brain tumors account for the majority of primary brain tumors in children. They are classified as low-grade gliomas (LGG) or high-grade gliomas (HGG), based on specific pathologic characteristics of the tumor, resulting in dis...
Pharmacologic intervention for attention-deficit hyperactivity disorder in preschoolers : is it justified? [0.03%]
学龄前儿童注意缺陷多动障碍的药物干预：有必要吗？
Jaswinder K Ghuman,Harinder S Ghuman
Jaswinder K Ghuman
Pharmacologic intervention for attention-deficit hyperactivity disorder (ADHD) in preschool children is a controversial issue. Non-pharmacologic interventions (psychosocial and restricted dietary interventions) have been shown to benefit op...
Counting the cost of meningococcal disease : scenarios of severe meningitis and septicemia [0.03%]
流行性脑膜炎疾病带来的经济损失：严重脑膜炎和败血症的场景模拟
Claire Wright,Rebecca Wordsworth,Linda Glennie
Claire Wright
Background: Meningococcal disease can result in severe disabling sequelae, but there is no published information about the lifelong rehabilitation costs of patients with severe outcome in the UK. As cost-effectiveness stu...
Gastroesophageal reflux disease in neonates and infants : when and how to treat [0.03%]
婴儿胃食管反流病的治疗时机及方法
Steven J Czinn,Samra Blanchard
Steven J Czinn
Gastroesophageal reflux (GER) is defined as the involuntary retrograde passage of gastric contents into the esophagus with or without regurgitation or vomiting. It is a frequently experienced physiologic condition occurring several times a ...
Caroline M Perry
Caroline M Perry
Paliperidone, the major active metabolite of risperidone, is an atypical antipsychotic agent formulated as an extended-release (ER) tablet suitable for once-daily oral administration. Paliperidone ER is approved for the treatment of adolesc...
Yasmin Gosiengfiao,Jennifer Reichek,David Walterhouse
Yasmin Gosiengfiao
Optimal management of rhabdomyosarcoma requires establishing the correct pathologic diagnosis, histologic sub-type, primary site, extent of disease (Stage), and extent of resection (Group). Based on these features, cooperative groups in Nor...
Apnea and oxygen desaturations in children treated with opioids after adenotonsillectomy for obstructive sleep apnea syndrome: a prospective pilot study [0.03%]
腺样扁桃体切除术后治疗阻塞性睡眠呼吸暂停综合征的儿童阿片类药物治疗期间的呼吸暂停和低氧血症：一项前瞻性初步研究
Justin D Khetani,Parvaz Madadi,Doron D Sommer et al.
Justin D Khetani et al.
Background: Recent case reports have alerted the medical community of fatality in children receiving codeine after tonsillectomy and/or adenoidectomy for obstructive sleep apnea syndrome. ...
When to start, what to start and other treatment controversies in pediatric HIV infection [0.03%]
儿科HIV感染的治疗时机、如何治疗及其他争议问题
Anna Turkova,Rachel H Webb,Hermione Lyall
Anna Turkova
Over the last decade there have been dramatic changes in the management of pediatric HIV infection. Whilst observational studies and several randomized control trials (RCTs) have addressed some questions about when to start antiretroviral t...
Pharmacoeconomic spotlight on rotavirus vaccine RIX4414 (Rotarix™) in the prevention of rotavirus gastroenteritis in developing countries [0.03%]
轮状病毒疫苗RIX4414（Rotarix™）在预防发展中国家轮状病毒胃肠炎中的药物流行病学展望
Greg L Plosker
Greg L Plosker
This article provides an overview of the clinical profile of rotavirus vaccine RIX4414 (Rotarix™) in the prevention of rotavirus gastroenteritis (RVGE) in developing countries, followed by a review of pharmacoeconomic analyses with the vac...
Heather J Zar,Michael E Levin
Heather J Zar
Asthma is the most common chronic disease in children in many low- and middle-income countries. In these settings, the burden of childhood asthma is increasing and is associated with severe disease. There are a number of challenges to provi...