Tocilizumab: a review of its use in the treatment of juvenile idiopathic arthritis [0.03%]
托珠单抗治疗儿童关节炎药物分析报告综述
James E Frampton
James E Frampton
Tocilizumab (RoActemra(®); Actemra(®)) is a recombinant humanized monoclonal antibody that acts as an interleukin-6 receptor antagonist. Both in the US and EU, tocilizumab has been approved for the treatment of two subtypes of juvenile id...
Quality of life in children and adolescents with autism spectrum disorders: what is known about the effects of pharmacotherapy? [0.03%]
孤独症谱系障碍儿童和青少年的生活质量：关于药物治疗效果的研究进展知多少？
Wendy N Moyal,Catherine Lord,John T Walkup
Wendy N Moyal
A diagnosis of autistic spectrum disorder (ASD), now estimated to affect one in 88 children, requires deficits in social communication and interactions, and restricted interests and/or repetitive behaviors. Almost all children with ASD have...
Erika E Vorhies,David Dunbar Ivy
Erika E Vorhies
Pulmonary arterial hypertension (PAH) is a rare disease in infants and children that is associated with significant morbidity and mortality. The disease is characterized by progressive pulmonary vascular functional and structural changes re...
Giant cell tumor of bone in childhood: clinical aspects and novel therapeutic targets [0.03%]
儿童骨巨细胞瘤的临床特点及新的治疗靶点
Noah Federman,Earl W Brien,Vivek Narasimhan et al.
Noah Federman et al.
Giant cell tumor of bone (GCTB) is a rare primary bone tumor that primarily affects young adults, but can be seen in children. The primary modality of treatment is surgical resection; however, this is not always possible given the location ...
Authors' reply to Eugenio Grillo: clinical management of seizures in newborns: diagnosis and management [0.03%]
对尤金尼奥·格力洛的回复：新生儿惊厥的临床处理：诊断和治疗
Linda G M van Rooij,Marcel P H van den Broek,Carin M A Rademaker et al.
Linda G M van Rooij et al.
Comment on: "Clinical management of seizures in newborns: diagnosis and treatment" [0.03%]
关于“新生儿癫痫发作的临床管理：诊断与治疗”的述评
Eugenio Grillo
Eugenio Grillo
A comparison of the efficacy and tolerability of oxcarbazepine oral suspension between infants and children with epilepsy: a retrospective chart review at a single medical center in Taiwan [0.03%]
奥卡西平口服悬液治疗台湾地区婴幼儿及儿童癫痫患者疗效和耐受性的回顾性分析：单中心研究报告
Shu-Hao Wei,Cheng-Chao Liu,Pi-Chuan Fan
Shu-Hao Wei
Background: Few clinical studies have assessed the efficacy and safety of oxcarbazepine (OXC) oral suspension in Asian pediatric patients and particularly in infants. The aim of this study was to investigate and compare t...
Endocrine therapy for growth retardation in paediatric inflammatory bowel disease [0.03%]
儿科炎症性肠病生长障碍的内分泌治疗
Mabrouka A Altowati,Richard K Russell,S Faisal Ahmed
Mabrouka A Altowati
Inflammatory bowel disease, particularly Crohn's disease (CD), can potentially cause growth failure during childhood as well as a reduction in final adult height. The underlying mechanism is multifactorial and includes poor nutrition, chron...
13-valent pneumococcal conjugate vaccine: a review of its use in infants, children, and adolescents [0.03%]
肺炎球菌多糖结合疫苗的临床应用分析及免疫桥接评价——以13价肺炎球菌结合疫苗为例
Greg L Plosker
Greg L Plosker
The 13-valent pneumococcal conjugate vaccine (Prevenar 13(®); Prevnar 13(®)) [PCV13] includes 13 serotype-specific polysaccharides of Streptococcus pneumoniae conjugated individually to non-toxic diphtheria CRM197 protein, thus providing ...
Impact of pneumococcal conjugate vaccines on microbial epidemiology and clinical outcomes of acute otitis media [0.03%]
肺炎球菌结合疫苗对急性中耳炎微生物流行病学和临床结果的影响
Isabelle Hau,Corinne Levy,Laurence Caeymaex et al.
Isabelle Hau et al.
Acute otitis media (AOM) is the leading bacterial infection in childhood and the main reason for antibiotic prescriptions in children. The success of pneumococcal conjugate vaccines (PCVs) in reducing invasive pneumococcal disease has been ...