Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome in Children-From Pathogenesis to Treatment Strategies: A Comprehensive Review [0.03%]
儿童周期性发热、口腔溃疡、咽炎和颈部淋巴结炎(PFAPA)综合征：从发病机制到治疗策略的全面综述
Federica Anselmi,Perrine Dusser,Isabelle Kone-Paut
Federica Anselmi
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is the most frequent periodic fever syndrome in non-Mediterranean children, usually manifesting before the age of 5 years. It is characterized by clock...
Levetiracetam Versus Fosphenytoin Infusions as Second-Line Treatment for Pediatric Status Epilepticus: A Multicenter Study Examining Effectiveness, Tolerability, and Ease of Use [0.03%]
丙戊酸钠与左乙拉西坦治疗儿童持续状态的多中心研究：有效性、耐受性和使用便捷性比较研究
Armelle Hornard,François Severac,Vincent Laugel et al.
Armelle Hornard et al.
Background and objectives: Status epilepticus is a life-threatening neurological emergency that requires rapid and effective treatment to prevent long-term complications or death. Traditionally, phenytoin and its prodrug ...
Effective Sirolimus Use in Prenatal and Postnatal Management of Symptomatic Extensive Congenital Capillary-Lymphatic-Venous Malformations (CLVMs): A Report of Two Cases [0.03%]
西罗莫司在重度先天性毛细血管-淋巴管-静脉畸形(CLVM)的产前产后治疗中的应用：两例报道
Anna Klosowska,Malgorzata Styczewska,Malgorzata A Krawczyk et al.
Anna Klosowska et al.
Introduction: Congenital capillary-lymphatic-venous malformations (CLVMs) often result in life-threatening complications, which may begin in utero. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been suc...
Physiologically Based Pharmacokinetic Modeling-Based Evaluation of Current Carbamazepine and Valproic Acid Dosing Guidelines for Pediatric Epilepsy Treatment [0.03%]
基于生理的药代动力学模型对儿童癫痫治疗中当前卡马西平和丙戊酸钠给药指南的评估
Joyce E M van der Heijden,Violette Gijsen,Anne M van Uden et al.
Joyce E M van der Heijden et al.
Background: Carbamazepine and valproic acid (VPA) are long-standing treatments for epilepsy in children. Interestingly, they display unique drug disposition characteristics, and maturation of drug metabolizing enzymes fur...
Association of Serum Levels of Ustekinumab, Vedolizumab, and Faecal Calprotectin in Paediatric Patients with Inflammatory Bowel Diseases: A Prospective Observational Study [0.03%]
英夫利昔单抗、维多珠单抗和粪便钙卫蛋白的血清水平与儿童炎症性肠病的相关性：一项前瞻性观察研究
J Bronsky,K Zarubova,I Copova et al.
J Bronsky et al.
Background and objectives: Ustekinumab (USTE) and vedolizumab (VEDO) are increasingly used in paediatric patients with inflammatory bowel diseases (pIBD). However, data on the usefulness of therapeutic drug monitoring (TD...
A Systematic Review of Anti-TNF and Anti-IL-6 Treatments for Pediatric Takayasu Arteritis: Addressing a Therapeutic Dilemma [0.03%]
抗TNF和抗IL-6疗法治疗儿童Takayasu动脉炎的系统评价：解决一个治疗难题
Ezgi Deniz Batu,Seher Sener
Ezgi Deniz Batu
Background and objectives: Takayasu arteritis (TAK) is a rare large-vessel vasculitis primarily affecting young female patients, with pediatric cases being even rarer. Biologic therapies, such as anti-tumor necrosis facto...
Clinical Study to Evaluate the Possible Efficacy and Safety of L-Arginine in Children with Sickle Cell Disease and Increased Tricuspid Regurgitant Jet Velocity: a Randomized Controlled Trial [0.03%]
评估L-精氨酸在增加三尖瓣反流射流速度的镰状细胞病儿童中的有效性和安全性的临床研究：一项随机对照试验
Dalia A Gomaa,Sahar M El-Haggar,Mohamed R El-Shanshory et al.
Dalia A Gomaa et al.
Background: Pulmonary hypertension (PH) is a common chronic complication of sickle cell disease (SCD), and patients at risk for PH can be identified by measuring tricuspid regurgitant jet velocity (TRJV). We looked for th...
Comment on "Role of mTOR Inhibitors in Pediatric Liver Transplant Recipients: A Systematic Review" [0.03%]
对“mTOR抑制剂在儿童肝移植受者中作用的系统评价”的评论
Emma Reed,Riya Yadav,Alexandra Mannino et al.
Emma Reed et al.