Caring for Older Adults with Acute Myeloid Leukemia: Best Practices for Aligning Patient Fitness and Preference with Available Therapies [0.03%]
急性髓系白血病老年人的治疗:最佳实践,协调患者的耐受性和偏好与可用疗法之间的关系
Stephanie Franco,Christopher Wanjiku,Daniel R Richardson
Stephanie Franco
Major advances in drug development and supportive care have led to a paradigm shift in the management of many of the aspects of clinical care for older adults with acute myeloid leukemia. The development of validated geriatric assessments n...
Associations of Polypharmacy, Diuretics and Antipsychotics with Injurious Falls: A Population-Based Cohort Study [0.03%]
多种药物联用、利尿剂和抗精神病药与跌倒受伤的关系:基于人群的队列研究
Tewodros Yosef,Julie A Pasco,Monica C Tembo et al.
Tewodros Yosef et al.
Objective: Population ageing increases multimorbidity, which in turn contributes to polypharmacy, elevating fall risk through drug interactions and adverse effects on cognition or balance. Although polypharmacy is recogni...
The Association Between Anticholinergic Burden and Treatment-Related Complications in Older Adults with Cancer [0.03%]
抗胆碱能负担与老年癌症患者相关并发症之间的关系
Edwin J Brokaar,Stella Trompet,Johanneke E A Portielje et al.
Edwin J Brokaar et al.
Background: Older adults constitute more than 50% of newly diagnosed cancer cases and polypharmacy is highly prevalent in this population. The Anticholinergic Burden (ACB) score quantifies the cumulative anticholinergic e...
Age-Specific Considerations in Bronchiectasis Management: Focus on Older Adults with Emphasis on Anti-inflammatory Treatment [0.03%]
支气管扩张症治疗中的年龄因素考量:重点关注老年人群及其抗炎治疗
Maria Gabriella Matera,Vito De Novellis,Raffaella Pagliaro et al.
Maria Gabriella Matera et al.
Bronchiectasis is increasingly recognized as a chronic inflammatory airway disease involving persistent immune dysregulation, recurrent infection, and progressive lung tissue damage. Older adults bear a particularly high burden of bronchiec...
Bronchiectasis in Older Adults: Distinctive Epidemiology, Etiology, Diagnosis, and Clinical Evolution Compared with Younger Populations [0.03%]
老年人支气管扩张的流行病学、病因、诊断和临床经过与年轻人的区别
Mario Cazzola,Fabio Perrotta,Raffaella Pagliaro et al.
Mario Cazzola et al.
Non-cystic fibrosis bronchiectasis is increasingly recognized as a major cause of chronic respiratory morbidity, particularly among older adults. Its rising prevalence is largely attributable to improved diagnostic imaging and heightened cl...
Bipolar Disorder in Older Adults: A Comprehensive Overview of Pharmacotherapy Patterns and Clinical Considerations [0.03%]
老年抑郁症患者的药理治疗模式和临床考虑的全面概述
Bashar Asir,Majd Al-Soleiti,Balwinder Singh
Bashar Asir
In older adults, bipolar disorder (BD) frequently presents atypically, with manic symptoms manifesting as irritability or confusion rather than euphoria. Cognitive impairments, including mild cognitive impairment and dementia, can obscure o...
Impact of Age on Bleeding, Stroke, and Mortality in Edoxaban-Treated Patients with Atrial Fibrillation: Results from the ETAF-TR Registry [0.03%]
年龄对房颤口服艾多沙班患者的出血、卒中及全因死亡率的影响:来自ETAF-TR登记研究的结果
Oğuzhan Çelik,Ozcan Basaran,Turhan Turan et al.
Oğuzhan Çelik et al.
Background: Data on age-specific outcomes in patients with atrial fibrillation (AF) treated with edoxaban in real-world settings are limited; this prespecified analysis of the ETAF-TR study aimed to investigate the influe...
Nikhil Jaganathan,David Brower,William J Healy
Nikhil Jaganathan
Older individuals frequently suffer from obstructive sleep apnea yet present with less severe symptoms than younger counterparts. Diagnosing obstructive sleep apnea in older adults poses unexpected challenges owing to poor specificity of sc...
Correction: Guideline-Directed Heart Failure Pharmacotherapy in Adults Aged ≥75 Years: Evidence Gaps, Tolerability, and Implications for Clinical Practice [0.03%]
关于≥75岁成人慢性心力衰竭药物治疗的指导:证据空白,耐受性和临床实践意义
Rémi Esser,Olivier Maurou,Marine Larbaneix et al.
Rémi Esser et al.
Published Erratum
Drugs & aging. 2026 Jul 6. DOI:10.1007/s40266-026-01308-7 2026
Austin Barry,Lindsay N Helget,Ted R Mikuls
Austin Barry
Gout is the most prevalent inflammatory arthritis worldwide and disproportionately affects older adults, who frequently have comorbid conditions such as chronic kidney disease and cardiovascular disease that lead to polypharmacy and complic...