Niki G Mourelatou,Eleni Rebelos,Michael Hughes et al.
Niki G Mourelatou et al.
The aging population is steadily increasing, representing a significant portion of the global population. Vitamin D deficiency is highly prevalent, particularly among older adults and has been implicated in the pathogenesis of various chron...
Marina De Castro Fidalgo E Costa,Frederique Ponchel,Kierran Flack et al.
Marina De Castro Fidalgo E Costa et al.
Osteoarthritis (OA) is a leading cause of disability worldwide, characterised by chronic pain and reduced quality of life. Despite its prevalence, pharmacotherapy options remain limited. Inflammation has emerged as a promising target, with ...
Applying the Bradford Hill Criteria to Assess the Independent Causal Roles of Aging and Medication in Frailty Progression: A Systematic Review [0.03%]
利用布拉德福德·希尔标准评估衰老和药物在脆弱性进展中的独立因果作用：系统评价
Subindra Kazi Thapa,Jia Li,John Mach et al.
Subindra Kazi Thapa et al.
Background: The scientific literature, including systematic reviews and meta-analyses, has frequently described associations between aging, medication use, and frailty, without evaluation of their independent causation. T...
Australian Polypharmacy Trends Between 2013 and 2024: A Repeated Cross-Sectional Study in the Adult Population [0.03%]
2013至2024年澳大利亚成人多药治疗趋势变化的重复横断面研究
Georgie B Lee,Christopher Etherton-Beer,Julie A Pasco et al.
Georgie B Lee et al.
Aim: The aim of this repeated cross-sectional study was to estimate polypharmacy prevalence and trends in Australian adults between 2013 and 2024. Methods...
Pharmacist-Led Deprescribing Interventions for Older Adults with Polypharmacy: A Retrospective Cohort Study of Community Pharmacy Practice in Japan [0.03%]
日本社区药房实践中的药师主导的减少处方干预措施：一项针对用药复杂老年患者的回顾性队列研究
Kenji Fujita,Noriko Sato,Ayumi Okizaki et al.
Kenji Fujita et al.
Background: Global aging makes polypharmacy in older adults a critical concern. Pharmacist-led deprescribing shows promise, but lacks routine implementation. Japan introduced "the Medication Adjustment Support Fee (the Ad...
Barbara Cvenkel,Miriam Kolko
Barbara Cvenkel
Glaucoma is one of the leading causes of blindness and its prevalence increases with age. The most common form, primary open-angle glaucoma, is a chronic, slowly progressive optic neuropathy characterised by the loss of retinal ganglion cel...
Therapeutic Management of Glucocorticoid-Induced Osteoporosis with a Focus on Older Adults: A Narrative Review [0.03%]
以老年人为重点的糖皮质激素诱导性骨质疏松症治疗管理综述
Elena Tsourdi,Ulrike Baschant,Martina Rauner et al.
Elena Tsourdi et al.
Glucocorticoid-induced osteoporosis is the most common cause of secondary osteoporosis and constitutes an important health problem, associated with an increased risk of fractures, significant morbidity and mortality, and long-term decreased...
Diabetic Peripheral Neuropathy: New Diagnostics and Treatment Perspectives [0.03%]
糖尿病外周神经病的诊断及治疗新观点
Michal Dubský,Dominika Sojáková,Vladimira Fejfarová et al.
Michal Dubský et al.
Diabetic peripheral neuropathy (DPN) is one of the most significant chronic complications in people with diabetes. It is a highly heterogeneous condition that affects various parts of the nervous system and presents with a wide range of sym...
Cross-Sectional and Longitudinal Analyses of the Association Between Statin Use and Age-Related Hearing Loss [0.03%]
他汀类药物使用与年龄相关性听力下降的横断面及纵向研究分析
Lizmarie G Maldonado,Lois J Matthews,Katharine A Fernandez et al.
Lizmarie G Maldonado et al.
Background: Emerging evidence in animal models and humans suggests that statins may provide partial protection against noise-induced and drug-induced hearing loss. However, evidence for protection against age-related hear...
Appropriate Use of Proton Pump Inhibitors in Older Adults: Concerns and Solutions [0.03%]
关注和解决老年人群 proton pump inhibitor 使用中的问题
Jennifer Bolt,Wade Thompson,Colleen Inglis
Jennifer Bolt
Proton pump inhibitors (PPIs) are amongst the most commonly prescribed medications worldwide. Clinical practice guidelines identify clear indications for short-term and long-term use; however, many older adults are prescribed potentially un...