Correction: How is Levetiracetam Monotherapy Currently Monitored in Pregnancy? A Systematic Review [0.03%]
关于利维坦醋胺妊娠期单药治疗当前监测方式的更正：系统性回顾
Tessa Rademaker,Yeonkyung Goo,May Ching Soh et al.
Tessa Rademaker et al.
Published Erratum
Clinical pharmacokinetics. 2025 Dec 1. DOI:10.1007/s40262-025-01600-6 2025
Factors Accounting for Pharmacodynamic Variability of Basal Insulin Preparations in Euglycemic Clamp Settings in Healthy Individuals [0.03%]
健康人在等血糖钳夹条件下基础胰岛素制剂药动学变异的影响因素分析
Hui Liu,Ting Li,Hongling Yu et al.
Hui Liu et al.
Background: The euglycemic clamp technique is a standard method for assessing the pharmacokinetics (PK) and pharmacodynamics (PD) of insulin biosimilars compared to their reference products. Despite similar pharmacokineti...
Design Optimization for Developing Population Pharmacokinetic Models in Critically Ill Children: Application to Teicoplanin, Piperacillin and Meropenem [0.03%]
重症儿童群体药代动力学模型发展的设计优化：泰阁菌素、哌拉西林和美罗培南的应用
Gastón García-Orueta,Laura Butragueño-Laiseca,María José Santiago et al.
Gastón García-Orueta et al.
Background and objective: Population pharmacokinetic (popPK) models in pediatric patients are essential to optimize dosing and ensure therapeutic efficacy. However, study designs are often not fully optimized, leaving roo...
Correction: Population Pharmacokinetics Analysis of Infliximab in up to 10‑Year‑Old Patients with Paediatric Inflammatory Bowel Disease: Label‑Recommended Dose Fails to Achieve Therapeutic Target Concentration [0.03%]
纠正：英夫利西单抗治疗儿童炎症性肠病患者（≤10岁）的群体药代动力学分析：推荐剂量无法达到药物浓度有效阈值
Q Zhao,M M E Jongsma,S A Vuijk et al.
Q Zhao et al.
Published Erratum
Clinical pharmacokinetics. 2025 Nov 28. DOI:10.1007/s40262-025-01599-w 2025
Population Pharmacokinetics of Levosimendan and its Metabolites OR-1855 and OR-1896 in Critically Ill Adults, Neonates and Infants on Veno-Arterial ECMO [0.03%]
体外膜氧合(ECMO)情况下重症成人、新生儿和婴儿左西孟丹及其代谢产物OR-1855和OR-1896的群体药代动力学研究
Stéphane Bertin,Monia Guidi,David Haefliger et al.
Stéphane Bertin et al.
Background and objective: Levosimendan is an inotrope and vasodilator agent commonly used in critical care, particularly to facilitate weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO). However, cri...
Population Pharmacokinetics of Propofol in Critically Ill Patients with and Without Extracorporeal Membrane Oxygenation [0.03%]
体外膜氧合患者和非体外膜氧合患者的异丙酚人群药代动力学研究
Stéphane Bertin,David Haefliger,Thomas Mercier et al.
Stéphane Bertin et al.
Background and objective: Propofol is commonly used in critically ill patients on extracorporeal membrane oxygenation (ECMO). Although ECMO may theoretically affect drug pharmacokinetics (PK) through various mechanisms, d...
TLD-1, a Novel Liposomal Doxorubicin, in Patients with Solid Tumors: Comparative Pharmacokinetics and Final Results of a Multicenter Phase 1 Study (SAKK 65/16) [0.03%]
新型脂质体阿霉素TLD-1治疗实体瘤患者：一项多中心I期研究（SAKK 65/16）的比较药代动力学和最终结果
Marian Klose,Ilaria Colombo,Katrin Gobat et al.
Marian Klose et al.
Background and objective: Targeted liposomal doxorubicin (TLD-1) is a novel PEGylated liposomal doxorubicin (PLD) with optimized formulation characteristics, developed to improve the benefit-risk profile of PLD. This rand...
Clinical Pharmacokinetic-Pharmacodynamic Relationships of Pharmacological Strategies for Attenuating p-Cresyl Sulfate in Patients with Kidney Disease [0.03%]
肾病患者药理学策略减轻对甲基硫酸盐的临床药物浓度-效应关系
Puja Dhungana,Andrew Dam,Tony K L Kiang
Puja Dhungana
p-Cresyl sulfate (pCS) is a highly toxic uremic compound that is produced from tyrosine and phenylalanine in the gut and primarily excreted renally. In patients with kidney dysfunction, the accumulation of pCS can lead to the worsening of k...
Population Pharmacokinetic Modeling of Oxcarbazepine and Its Active Metabolite 10-Monohydroxy Derivative to Inform Dosing in Children with Obesity [0.03%]
用于肥胖儿童奥卡西平剂量调整的群体药动学研究及其活性代谢产物10-单羟基衍生物的研究
Jaydeep Sinha,Kanecia Zimmerman,Stephen J Balevic et al.
Jaydeep Sinha et al.
Background: Oxcarbazepine (OXZ) is an antiepileptic drug whose pharmacological effect is primarily mediated by its active metabolite, 10-monohydroxy derivative (MHD). OXZ is approved for use in adults and children older t...