Emerging Therapeutic Strategies in Cutaneous T-Cell Lymphoma: A Comprehensive Review of Clinical Trials [0.03%]
皮病T细胞淋巴瘤治疗策略的临床研究综合述评
Yoni Sacknovitz,Rachel Ma,Christina M Bear et al.
Yoni Sacknovitz et al.
Background: Cutaneous T-cell lymphomas (CTCL), including mycosis fungoides (MF) and Sézary syndrome (SS), are rare non-Hodgkin lymphomas characterized by skin-homing malignant T cells. While early-stage disease carries f...
Long-Term Efficacy and Safety of Ritlecitinib in Adults and Adolescents with Alopecia Areata: 3-Year Results from the ALLEGRO Phase 2b/3 and ALLEGRO-LT Phase 3 Clinical Studies [0.03%]
长期评价利特西替尼治疗斑秃成人和青少年患者的疗效和安全性：ALLEGRO II期b/III期和ALLEGRO-LT III期临床研究的3年结果
Maryanne Senna,Jennifer Soung,Ignasi Figueras et al.
Maryanne Senna et al.
Background/objective: Ritlecitinib, an oral JAK3/TEC family kinase inhibitor, demonstrated efficacy over 48 weeks in patients aged ≥ 12 years with alopecia areata (AA) in the ALLEGRO phase 2b/3 study and initial extensio...
Corrective and Restorative Dermatology in Cancer Survivors: An Urgent Unmet Need! [0.03%]
肿瘤幸存者的纠正性皮肤修复治疗：一个亟待解决的迫切需求！
Luca Rapparini,Timila Assia Touhouche,Davide Fattore et al.
Luca Rapparini et al.
The increasing efficacy of oncological therapies has led to a rapidly growing population of cancer survivors, shifting clinical attention from acute treatment-related toxicities to long-term and late sequelae. Among these, dermatological se...
Safety and Efficacy of Treatment with Dupilumab for up to 2 Years in Infants and Young Children with Atopic Dermatitis [0.03%]
dupilumab治疗婴幼儿期至学龄前中重度特应性皮炎长达2年的疗效和安全性
Amy S Paller,Eric L Simpson,Elaine C Siegfried et al.
Amy S Paller et al.
Background: Atopic dermatitis (AD) is a chronic inflammatory disease with a high clinical burden and risk of persistence in pediatric patients. Objective:...
Psychocutaneous Disorders in Pediatric and Adolescent Populations: A Narrative Review [0.03%]
儿科和青少年人群中的心理皮肤病学障碍：叙述性综述
Isabella J Tan,Alexis Mitelman,Mohammad Jafferany
Isabella J Tan
Psychocutaneous disorders (PCDs) in children and adolescents lie at the intersection of dermatology and psychiatry and include primary psychiatric conditions with cutaneous manifestations, dermatologic diseases with psychiatric sequelae, an...
Ritlecitinib for Severe Alopecia Areata: A 24-Week, Multicentre, Real-World Study [0.03%]
有关重度斑秃的一项为期24周的多中心真实世界研究：利特昔替尼的效果如何？
Michela Starace,Luca Rapparini,Francesca Pampaloni et al.
Michela Starace et al.
Background: Ritlecitinib, an oral selective inhibitor of Janus kinase 3 and the TEC family of kinases, has recently been approved for the treatment of severe alopecia areata, but real-world data are still limited. ...
Jaime Piquero-Casals,Clémence Bertold,Agustín Alomar et al.
Jaime Piquero-Casals et al.
Background: Vitiligo is a multi-factorial autoimmune skin disorder often triggered by environmental exposures. Although the exposome has gained attention, no systematic review has fully assessed its role in vitiligo. ...
Factors Associated with Symptomatic Dermographism: Findings from the UCARE PREVALENCE-D Study [0.03%]
UCARE PREVALENCE-D研究中与症状性皮肤划痕症相关的因素
Kanokvalai Kulthanan,Jonathan A Bernstein,Michael Rudenko et al.
Kanokvalai Kulthanan et al.
Background and objective: Symptomatic dermographism (SD), the most common chronic inducible urticaria subtype, manifests as strip-shaped, pruritic wheals after skin friction. Conclusive data on its associated factors are ...
Religious and Cultural Considerations for the Dermatologic Care of Muslim Communities: A Narrative Review of Patient-Centered Strategies [0.03%]
从以患者为中心的角度审视针对穆斯林社区皮肤病诊疗的文化和宗教影响：叙述性回顾
Yasser M Almansour,Ferdos Abdulkader,Deena Abdel-Gadir et al.
Yasser M Almansour et al.
Muslim patients may participate in religious and cultural practices that can affect their dermatologic health and influence their preferences regarding care and treatment. In this narrative review, we explore these topics and present cultur...
Icotrokinra: An Oral Interleukin-23 Receptor Antagonist Peptide for the Treatment of Psoriasis [0.03%]
伊科特罗克宁拉：用于治疗银屑病的口服白细胞介素-23受体拮抗肽
César Ferreira,Tiago Torres
César Ferreira
Psoriasis is a chronic, immune-mediated inflammatory disease with substantial impact on quality of life. While biologic therapies targeting interleukin (IL)-23 and IL-17 have set new efficacy and safety benchmarks, currently available oral ...