Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology [0.03%]
放射性皮纤维化：病理生理学、新兴疗法及皮肤病学的作用
Olivia M Burke,Sophie M Bilik,Caroline Dodson et al.
Olivia M Burke et al.
Radiotherapy-induced skin fibrosis is a chronic progressive complication of radiotherapy that impairs function, aesthetics, and quality of life yet remains under-recognized and undertreated. While acute cutaneous toxicities are typically tr...
Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments [0.03%]
女性雄激素性脱发：病理生理、临床评估和治疗的叙述性综述
Caitlin A Kearney,Anna L Brinks,Carli Needle Lawrence et al.
Caitlin A Kearney et al.
Androgenetic alopecia (AGA) affects nearly 50% of women during their lifetime, representing the most prevalent form of chronic hair loss in this population. Despite its high incidence, AGA in women remains underdiagnosed and undertreated, w...
Expert Recommendations for the Diagnosis and Management of Chronic Hand Eczema in the United States [0.03%]
美国慢性手部湿疹诊断和治疗专家推荐意见
Jonathan I Silverberg,David Cohen,Emma Guttman-Yassky et al.
Jonathan I Silverberg et al.
Chronic hand eczema (CHE) is an inflammatory skin disease localized to the hands and wrists that lasts for more than 3 months or relapses at least twice per year. The diagnosis, treatment, and management of CHE presents clinical challenges ...
Air Pollution and Skin Diseases: A Systematic Review of Epidemiological Evidence [0.03%]
空气污染与皮肤病的流行病学证据系统回顾
Nidhi Singh,Tamara Schikowski,Jean Krutmann
Nidhi Singh
Background: A growing number of epidemiological studies have suggested a causal link between air pollution and several common skin diseases. However, considerable variation in study design and heterogeneous results make i...
Long-Term Real-World Evaluation of Abrocitinib in Moderate-to-Severe Atopic Dermatitis Across a Diverse Patient Population in a Multi-site Hospital System [0.03%]
艾伯利珠单抗治疗中至重度特应性皮炎的长期真实世界评价：多中心医院系统中的多样患者人群研究
Megan Lau,Joseph Largen,Jasmine Levine et al.
Megan Lau et al.
Background: Although clinical trials have demonstrated the efficacy and safety of abrocitinib in atopic dermatitis, there remains a lack of comprehensive long-term real-world studies across diverse patient populations. ...
Cutaneous Manifestations of Emerging Arbovirus Infections Including West Nile, Dengue, Zika, Chikungunya, Usutu, and Toscana Viruses: A Clinical Overview for Dermatologists [0.03%]
包括西尼罗病毒、登革病毒、寨卡病毒、 chickungunya 、乌苏图和托斯卡纳病毒等新现虫媒病毒感染的皮肤表现：给皮肤科医生的临床概述
Franco Rongioletti,Francesco Drago
Franco Rongioletti
Arboviral infections, notably those caused by West Nile virus (WNV), Dengue virus (DENV), Zika virus (ZIKV), and Chikungunya virus (CHIKV), represent a growing global health concern due to their expanding geographic distribution and evolvin...
Switching from Dupilumab to Upadacitinib in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis After Inadequate Response to Dupilumab: Efficacy and Safety Results from Period 2 of Phase 3b/4 Study (LEVEL UP) [0.03%]
对于Dupixent应答不足的中度至重度特应性皮炎成人和青少年患者从Dupixent转换为Upadacitinib：IIIb/IV期研究（LEVEL UP）第二阶段的有效性和安全性结果
Christopher G Bunick,Nina Magnolo,Angela Moore et al.
Christopher G Bunick et al.
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by intense itch and eczematous skin lesions. Upadacitinib, a selective oral Janus kinase inhibitor, and dupilumab, a monoclonal antib...
Nicotinamide for Skin Cancer Chemoprevention: The Jury Was Out and Still is [0.03%]
尼古酸作为皮肤癌化学预防手段：尚未盖棺定论
Eugene Tan,Hywel C Williams
Eugene Tan
Nicotinamide has been widely promoted as a low-cost safe chemopreventive agent against non-melanoma skin cancer. A recent large retrospective study of more than 33,000 US veterans reported a 14% reduction in overall skin cancer risk and a 2...
Barbara Horváth,Marjolein A J Hiel,Anne-Lise Strandmoe et al.
Barbara Horváth et al.
Pemphigus is a group of rare autoimmune blistering disorders affecting the skin and mucosal surfaces, caused by pathogenic immunoglobulin G (IgG) autoantibodies targeting desmosomal cadherins, specifically desmoglein-1 and desmoglein-3, whi...