Systemic Comorbidities of Keloid and Hypertrophic Scars: A Phenome-Wide Association Study in a Multiethnic U.S. Pediatric Cohort [0.03%]
儿童瘢痕增生的系统共病：美国多民族儿科队列的表型广义关联研究
Fatemeh Vahidnezhad,Noosha Samieefar,Mahdi Akbarzadeh et al.
Fatemeh Vahidnezhad et al.
Background: Excessive scarring (ES), including keloids and hypertrophic scars, impairs function, appearance, and quality of life in children. Its pediatric comorbidity spectrum is not well defined, limiting anticipatory g...
Efficacy and Safety of Oral Janus Kinase Inhibitors in Adults and Adolescents with Alopecia Areata: A Systematic Review and Meta-Analysis of Randomised Controlled Trials [0.03%]
Janus激酶抑制剂治疗成人和青少年斑秃疗效及安全性的系统评价和 meta 分析
Samuel Morriss,Chuan Hui Foo,Emily Lin et al.
Samuel Morriss et al.
Background: Alopecia areata is an autoimmune disorder characterised by T-cell-mediated damage of hair follicles, resulting in non-scarring hair loss that can progress to complete scalp (alopecia totalis) or body hair loss...
Correction to: Long-Term Efficacy and Safety of Ritlecitinib in Adults and Adolescents with Alopecia Areata: 3-Year Results from the ALLEGRO Phase 2b/3 and ALLEGRO-LT Phase 3 Clinical Studies [0.03%]
特异性治疗成人和青少年斑秃的ritlecitinib长期疗效和安全性：ALLEGRO二期b期/三期及ALLEGRO-LT三期临床研究的三年结果的更正
Maryanne Senna,Jennifer Soung,Ignasi Figueras et al.
Maryanne Senna et al.
Published Erratum
American journal of clinical dermatology. 2026 Jul 28. DOI:10.1007/s40257-026-01059-6 2026
Is Acanthosis Nigricans a Marker for Metabolic Syndrome? A Systematic Review [0.03%]
黑棘皮病是代谢综合征的标志吗？系统综述
Jordan Gillespie,Jaclyn Roland-McGowan,Kyra Diehl et al.
Jordan Gillespie et al.
Background/objective: Certain skin conditions are proven indicators of underlying systemic disease. Specifically, acanthosis nigricans (AN) is commonly associated with type 2 diabetes and insulin resistance. However, AN m...
Shared Mechanistic Pathways in Bullous Pemphigoid, Chronic Spontaneous Urticaria, Prurigo Nodularis, and Chronic Prurigo of Unknown Origin: Implications for Targeted Therapies [0.03%]
大疱性天疱疮、慢性自发性荨麻疹、结节性痒疹和原因不明的慢性痒疹中共享的发病机制途径：针对靶向治疗的意义
Enno Schmidt,Marta Ferrer Puga,Brian S Kim et al.
Enno Schmidt et al.
Bullous pemphigoid, chronic spontaneous urticaria, prurigo nodularis, and chronic prurigo of unknown origin are distinct chronic skin diseases with a high disease burden and an ongoing need for safe and effective therapies. Advances in our ...
The Role of Skin Surface pH in Age Associated Pruritus: Mechanistic and Clinical Insights [0.03%]
皮肤表面pH在与年龄相关的瘙痒症中的作用：机制和临床见解
Rafal M Pielak,Daniel C Butler
Rafal M Pielak
Skin aging is characterized by progressive structural and biochemical changes that impair epidermal barrier function, alter the cutaneous microbiome, and predispose to chronic pruritus. Epidermal thinning, reduced lipid synthesis, and slowe...
Updated Integrated Safety Analysis of Ritlecitinib up to ~ 5 Years in Patients with Alopecia Areata from the ALLEGRO Clinical Trial Program [0.03%]
贝勒研究项目中多达约5年期的ritalecinib更新综合安全分析在斑块型 alopecia areata 受试者中的疗效：一项IIb/III期临床试验
Maryanne Senna,Sameh Hanna,Rie Ueki et al.
Maryanne Senna et al.
Background: Ritlecitinib, an oral Janus kinase (JAK) 3/tyrosine kinase expressed in hepatocellular carcinoma (TEC) family kinase inhibitor, demonstrated safety in patients aged 12 years and older with alopecia areata (AA)...
A Systematic Review of Factors Influencing Adult Adherence to Topical Medications in Atopic Dermatitis [0.03%]
成人特应性皮炎外用药物依从性影响因素的系统评价
Stacey N Giuffre,Aditya Joshi,Camila R Marquez et al.
Stacey N Giuffre et al.
Background: Atopic dermatitis (AD) is a chronic inflammatory dermatosis requiring multifaceted treatment. Poor adherence to topical therapy hinders symptom management, highlighting the need to identify barriers influencin...
Circulating Tumor DNA as a Biomarker for Melanoma Prognosis and Therapy [0.03%]
循环肿瘤DNA作为黑色素瘤诊断和治疗标志物的作用
Isabel Heidrich,Sarah Urhahn,Christoffer Gebhardt et al.
Isabel Heidrich et al.
With more than 300,000 new cases diagnosed in 2022 and a projected rise in incidence until the year 2040, malignant melanoma remains a major global health challenge. Of note, immunotherapy has substantially improved survival outcomes, even ...
Eric L Simpson,Amy S Paller,Oscar Palomares et al.
Eric L Simpson et al.
Atopic dermatitis is a common inflammatory disorder affecting the skin, often associated with a strong disease burden and a long-term impact on patients' quality of life. Although most treatments for atopic dermatitis have been mainly focus...