Antidiabetic Activity of Moringa oleifera Aqueous Leaf Extract on Prediabetic Wistar Male Rats [0.03%]
摩拉摩拉果叶提取物对Wistar雄性糖尿病前期大鼠的抗糖尿病活性
Titing Nurhayati,Vita Murniati Tarawan,Happy Delia et al.
Titing Nurhayati et al.
Purpose: Diabetes mellitus is a chronic metabolic disorder linked to sedentary lifestyles, which reduces insulin sensitivity and increases hyperglycemia risk. Standard treatments include lifestyle changes and medications....
Repeated Levonorgestrel Administration Impairs Cognitive Function via Glutamatergic Transmission and CaMKII-PKA-BDNF Signaling in the Hippocampus of Female Wistar Rats [0.03%]
左炔诺孕酮反复暴露通过海马区谷氨酸能系统和CaMKII-PKA-BDNF信号通路损伤大鼠认知功能
Halimat Amin Abdulrahim,Noah Adavize Omeiza,Ganiu Jimoh Akorede et al.
Halimat Amin Abdulrahim et al.
Background: Levonorgestrel (LNG), a synthetic progestin widely used in emergency contraception, is increasingly taken frequently and often without medical supervision. With rising concerns that repeated exposure to such h...
Pyrazoline B Induces Oxidative Stress Mediated Toxicity, Cell Cycle Arrest, and Caspase-Independent Apoptosis in BT-474 Human Breast Cancer Cells [0.03%]
吡唑啉B通过诱导氧化应激毒性、细胞周期阻滞和无胱酶参与的细胞凋亡对BT-474人乳腺癌细胞产生作用
Hesti Lina Wiraswati,Pamungkas Bagus Satriyo,Muhammad Hasan Bashari et al.
Hesti Lina Wiraswati et al.
Introduction: Luminal subtype B breast cancer represents a clinically challenging subtype, accounting for nearly 40% of all breast cancers. However, clinical outcomes remain suboptimal due to challenges such as poor solub...
In vivo Therapeutic Inhibition of the Tp53-Induced Glycolysis and Apoptosis Regulator (TIGAR) by Intravenous Administration of an Anti-Oncological siRNA-Biopolymer, TI6752 (Tituxistatin), in a Preclinical Xenograft Model of Colorectal Cancer [0.03%]
一种抗癌siRNA-生物聚合物TI6752（tituxistatin）通过静脉给药在体外抑制结直肠癌异种移植模型中Tp53诱导的糖酵解和凋亡调节因子（TIGAR）的治疗作用研究
Carolyn K Harrod,Brenda Y Hernandez,Courtney Yates et al.
Carolyn K Harrod et al.
Introduction: The TP53-induced glycolysis and apoptosis regulator (TIGAR) is upregulated in many cancers and often correlates with poor clinical prognoses and serves as a key determinant of therapy-responsiveness. The TIG...
Colocasia Esculenta as a Potential Plant-Based Medicine: A Review on Its Bioactive Constituents and Pharmacological Activities [0.03%]
作为植物基药物的食用芋头的研究：其生物活性成分和药理作用综述
Reza Pertiwi,Gofarana Wilar,Sri Adi Sumiwi et al.
Reza Pertiwi et al.
Colocasia esculenta (L.) Scott, commonly known as taro, is a tuberous plant widely cultivated and utilized as a food source and traditional medicine in various cultures worldwide. Its ethnopharmacological significance, particularly in Asia,...
A Narrative Review of the Biological Activities of Anredera cordifolia (Ten). Steenis for Its Potential as a Natural Feed Additive for Livestock: Bridging Phytochemical Profile and in silico, in vitro, and in vivo Studies [0.03%]
龙牙草（藤）的生物学活性叙述性评审：作为天然饲料添加剂的潜力及其从植物化学谱型到基于计算机、体外和体内的研究之间的联系
Ken Ratu Gharizah Alhuur,Diky Ramdani,Indah Suasani Wahyuni et al.
Ken Ratu Gharizah Alhuur et al.
Antibiotic growth promoters (AGPs) are commonly used as feed additives to enhance livestock productivity; however, their side effects, such as antimicrobial resistance in both animal and human bacterial pathogens, have arisen, thus leading ...
Effects of Catha edulis Extract on Atorvastatin-Induced Myotoxicity in Rats: Biochemical and Histopathological Evidence [0.03%]
姜黄素对阿托伐他汀诱导的大鼠肌毒性的影响：生化和组织病理学依据
Abdulatef Mohammed Mohammed Abbas,Safia Abdulatef Abdulruhman Alrezami,Butheina Abdulwalli Al-Amrani
Abdulatef Mohammed Mohammed Abbas
Background: Rhabdomyolysis (RML) is a complex disorder caused by muscle cell injury and the subsequent release of intracellular components into circulation. Statins are widely used and generally well tolerated; however, s...
Artemisia annua Extract Ameliorates Atopic Dermatitis: Evidence from 3D Epidermal Model and Complementary in vitro Assays [0.03%]
Artemisia annua提取物改善特应性皮炎：来自三维表皮模型和补充体外实验的证据
Yuanyuan Tian,Lei Jiao,Yiran Li et al.
Yuanyuan Tian et al.
Background: Atopic dermatitis (AD) is a chronic and recurrent inflammatory skin disease. The disruption of the epidermal barrier and the inflammatory response are the key factors for the occurrence and development of this...
Neuroprotective Effects of Asiatic Acid on Autophagy and Mitochondrial Integrity in a Parkinson's Disease Cellular Model [0.03%]
祛痰汤通过调控自噬和线粒体功能改善帕金森病细胞模型中的神经保护作用
Athinan Prommahom,Tatcha Balit,Sunisa Somkana et al.
Athinan Prommahom et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder. PD patients mostly exhibit mitochondrial dysfunction and autophagic impairment. Asiatic acid (AA) is a triterpenoid with the highest antiox...
Antihypertensive Effects of Diosmetin in Hypertension-Induced Cardiovascular Abnormalities in Rats [0.03%]
染料木素对高血压诱导的大鼠心血管异常的降压作用
Banyaphon Jan-O,Metee Iampanichakul,Prapassorn Potue et al.
Banyaphon Jan-O et al.
Introduction: Hypertension is associated with cardiovascular dysfunction and remodeling. Diosmetin, a flavonoid isolated from citrus seeds, has various biological properties. This work investigated the effects of diosmeti...