Exploratory Review on Male Fertility Potential of Acetyl-Eugenol: Mechanistic Insights, Experimental Evidence, and Therapeutic Prospects [0.03%]
乙酰香酚对男性生育力影响的探索性综述：机制见解、实验证据和治疗前景
Ismahil Adekunle Adeniyi,Umar Uthman Shehu,Emmanuel Orire Ikuomola et al.
Ismahil Adekunle Adeniyi et al.
Male infertility contributes to nearly half of all infertility cases worldwide and is closely linked to oxidative stress, inflammation, endocrine imbalance, and environmental toxicant exposure, all of which impair spermatogenesis and sperm ...
High-Concentration Cyanidin-3-O-Glucoside Attenuates Palmitic Acid-Induced Oxidative Stress via ROS Suppression in Pancreatic β-Cells [0.03%]
高浓度花色苷-3-O-葡萄糖苷通过抑制ROS改善棕榈酸诱导的胰岛β细胞氧化应激损伤
Sasirin Chitwattananont,Sutthipong Sawasvirojwong,Chatchai Muanprasat
Sasirin Chitwattananont
Background: Type 2 diabetes mellitus (T2DM) is characterized by progressive β-cell dysfunction driven in part by palmitic acid (PA)-induced lipotoxicity. Cyanidin-3-O-glucoside (C3G) possesses antioxidant properties, but...
Hesperidin Mitigates Bisphenol-A Induced Oxidative Stress, Endocrine Disruption and Testicular Damage in Adult Male Wistar Rats [0.03%]
hesperidin对BPA所致成年Wistar大鼠氧化应激、内分泌干扰及睾丸损伤的改善作用
Augustine Oviosun,Ezinne Chidinma Oviosun,Ibe Micheal Usman et al.
Augustine Oviosun et al.
Introduction: Bisphenol A (BPA), a well-known endocrine disruptor, is newly emerging as causing male infertility by endocrine disturbances, induction of oxidative stress and testicular toxicity. This study investigates th...
Sub-Acute Toxicity Evaluation and Antiurolithiatic Activity of Tribulus terrestris Ethanol Extract in Rats [0.03%]
尖刚刺攀乙醇提取物的亚急性毒性评价及体外排石作用研究
Ahmed Al-Mohamadi,Imadeldin M Taj Eldin,Doa&#x;a Ibrahim et al.
Ahmed Al-Mohamadi et al.
Background: Tribulus terrestris (T. terrestris) is traditionally used in the management of urinary disorders; however, evidence regarding its safety upon repeated administration and its antiurolithiatic efficacy remains l...
Intraperitoneal Administration of Cardiolipin Enhances Mitochondrial Respiration in Skeletal Muscle of Male Mice [0.03%]
向小鼠腹腔内给药心磷脂可增强骨骼肌线粒体呼吸作用
Amanda Laplante,Andreas Bergdahl
Amanda Laplante
Purpose: Cardiolipin is a phospholipid located in the inner mitochondrial membrane and is released following myocardial ischemia-reperfusion injury. While cardiolipin has documented effects in several tissues, its impact ...
Advances on Ethnobotanical, Phytochemical, and Preclinical Studies of Strobilanthes crispus and Strobilanthes cusia (Acanthaceae) for Drug Development Purpose: A Narrative Review [0.03%]
药用植物假律草和毛菍（爵床科）的 ethnobotany、植物化学及临床前研究进展：药物研发目的综述型评论
Rani Rubiyanti,Yasmiwar Susilawati,Siti Mariam Binti Abdul Wahab et al.
Rani Rubiyanti et al.
Plants of the genus Strobilanthes are one of the most widespread vegetation in Southeast Asia. More than 100 metabolites, including alkaloids, fatty acids and derivatives, flavonoids and flavonoid glycosides, phenolic acids, sterols, and te...
Mangiferin Mitigates Ketamine-Induced Dopaminergic and Glial Dysregulation and Modulates Nrf2 Expression in a Rat Schizophrenia-Like Model [0.03%]
芒果苷通过调节核因子E2相关因子2表达缓解氯胺酮致大鼠精神分裂症样模型多巴胺能神经元及小胶质细胞异常
Victoria Onyemachi Chukwu,Godson Emeka Anyanwu,Nto Johnson Nto et al.
Victoria Onyemachi Chukwu et al.
Introduction: Schizophrenia involves dopaminergic dysregulation, oxidative stress, and glial activation within motor-cognitive circuits. Mangiferin, a polyphenolic C-glucoside from Mangifera indica, exerts antioxidant and...
Development and Validation of Bioanalytical Method for Efavirenz in Dried Blood Spot Using High Performance Liquid Chromatography-Photodiode Array [0.03%]
高效液相色谱-光电二极管阵列法测定干血点中依非韦伦的开发与验证
Dysaprita Nabila Putri,Yahdiana Harahap,Febrina Amelia Saputri
Dysaprita Nabila Putri
Efavirenz requires adequate serum concentrations (1-4 µg/mL) to ensure therapeutic efficacy and avoid central nervous system toxicity. Due to significant interindividual pharmacokinetic variability, therapeutic drug monitoring (TDM) is oft...
"Comparative Evaluation of Saussurea Lappa Root Extract Ointment and Standard Therapy on Second-Degree Burn Wound Healing in Rabbits" [0.03%]
兔二度烧伤创面修复过程中防风根提取物软膏与常规药物的疗效比较研究
Ali A Al-Mehdar,Abdullah H Maad,Ali Salman Al-Shami et al.
Ali A Al-Mehdar et al.
Background: Saussurea lappa is a traditional medicinal herb valued for its anti-inflammatory, antimicrobial, and antioxidant properties. Burn wounds are highly susceptible to infection and oxidative stress, which delay he...
Effect of Vulgarin and Epivulgarin on Ischemia-Reperfusion-Induced Pancreatic Injury in Rats: A Biochemical, Molecular, and Histopathological Evaluation [0.03%]
Vulgarin和Epivulgarin对大鼠缺血再灌注性胰腺损伤的生化、分子及组织学影响研究
Hassan N Althurwi,Rehab F Abdel-Rahman,Tariq M Aljarba et al.
Hassan N Althurwi et al.
Introduction: Ischemia/reperfusion (I/R) injury is a critical complication associated with pancreatic surgery, and transplantation, which frequently develops into acute pancreatitis due to increased oxidative stress and i...