A comparative study of DNA damage in patients suffering from diabetes and thyroid dysfunction and complications [0.03%]
糖尿病合并甲状腺功能障碍及并发症患者的DNA损伤比较研究
Nima V Thakkar,Sunita M Jain
Nima V Thakkar
Objective: The apoptotic DNA levels in blood leukocytes of patients with type 2 diabetes (T2D) and thyroid dysfunctionism were evaluated. Materials and me...
Mitochondrial therapy for Parkinson's disease: neuroprotective pharmaconutrition may be disease-modifying [0.03%]
线粒体医学治疗帕金森病：药用营养素可能具神经保护和改变疾病进程的作用
Richard Kones
Richard Kones
Progressive destruction of neurons that produce dopamine in the basal ganglia of the brain, particularly the substantia nigra, is a hallmark of Parkinson's disease. The syndrome of the Parkinsonian phenotype is caused by many etiologies, in...
In vitro cytotoxicity of combinations of dichloroacetate with anticancer platinum compounds [0.03%]
二氯乙酸与抗肿瘤铂类化合物组合的体外细胞毒性作用研究
Ulrike Olszewski,Thomas Tuxen Poulsen,Ernst Ulsperger et al.
Ulrike Olszewski et al.
Purpose: Dichloroacetate (DCA) inhibits pyruvate dehydrogenase kinase (PDK), and thus promotes glucose oxidation over glycolysis and induces apoptotic death of tumor cells. The present study investigated the potential of ...
Reporting of results of interventional studies by the information service of the National Institutes of Health [0.03%]
国立卫生研究院的信息服务对干预性研究结果的报道
Tatyana Shamliyan
Tatyana Shamliyan
The Food and Drug Administration Amendments Act of 2007 mandated that sponsors of applicable studies must provide results within one year of study completion. We aimed to analyze the factors associated with reporting of results from interve...
Clinical efficacy of beta1 selective adrenergic blockers in the treatment of neurocardiogenic syncope - a meta-analysis [0.03%]
β1受体阻滞剂治疗神经源性直立性低血压的临床疗效分析——一项meta分析研究
Srikanth Vallurupalli,Smita Das
Srikanth Vallurupalli
Background: Beta1 (B(1)) selective blockers have been widely used for the treatment of neurocardiogenic syncope though clinical trials have shown conflicting degrees of efficacy. ...
The interaction between clopidogrel and proton pump inhibitors (PPI): is there any clinical relevance? [0.03%]
氯吡格雷与质子泵抑制剂（PPI）的相互作用及其临床意义
Rakesh K Sharma,Hanumanth K Reddy,Rohit K Sharma et al.
Rakesh K Sharma et al.
The potential interaction between clopidogrel and proton pump inhibitors (PPI) in patients with acute coronary syndrome (ACS) raises serious concerns for cardiologists. However, in patients on this combination of drugs, there is no conclusi...
Sanjay Kalra,Navneet Agrawal,Satish Kumar et al.
Sanjay Kalra et al.
This article contains a review of the clinical aspects of testosterone replacement in androgen deficiency of the aging male. Ke...
Differences in hospital glycemic control and insulin requirements in patients recovering from critical illness and those without prior critical illness [0.03%]
既往重症与未患重症糖尿病患者住院期间的血糖控制和胰岛素需求的差异
April D Miller,Leslie M Phillips,Richard M Schulz et al.
April D Miller et al.
Introduction: Hospital patients recovering from critical illness on general floors often receive insulin therapy based on protocols designed for patients admitted directly to general floors. The objective of this study is...
Daniel D Bennett,Maro Ohanian,Christian T Cable
Daniel D Bennett
New clinical indications for rituximab seem to appear every day. This review will trace the use of this monoclonal antibody from lymphoid malignancy, to classic autoimmune disease, and specifically severe autoimmune skin diseases. The histo...
Sanjay Kalra,Bharti Kalra,Satish Kumar et al.
Sanjay Kalra et al.
Diabetes mellitus is part of the insulin resistance syndrome, which includes hypertension, dyslipidemia, and obesity as its other components. Conversely, insulin resistance is a major pathophysiologic factor in the development of type 2 dia...