Reduced Prescription of Baloxavir After Suspected Prevalence of a Baloxavir-Resistant Influenza Virus Strain and the Emergence of SARS-CoV-2 in a Tertiary Hospital in Japan [0.03%]
在一家日本三级医院中，疑似存在一种巴洛沙韦耐药的流感病毒株并且新冠SARS-CoV-2出现后，减少巴洛沙韦的处方量
Yasuhiro Kamioka,Shota Kashiwagura,Masafumi Seki
Yasuhiro Kamioka
Objective: The use of baloxavir, a new anti-influenza agent, began in Japan from the 2018 to 2019 season and became the focus of attention due to its efficient viral reduction ability; therefore, we should know the prescr...
Hydroxychloroquine in COVID-19: The Study Points to Premature Decisions on Efficacy While Bells Ringing for Safety [0.03%]
COVID-19中的羟氯喹：研究对有效性的结论为时过早，但安全警钟已经响起
Sitaram Khadka,Dhan Bahadur Shrestha,Pravash Budhathoki et al.
Sitaram Khadka et al.
Coronavirus disease (COVID-19) pandemic has been a global disease burden. It has affected more than sixteen million people in the world within seven months of its first outbreak in Wuhan. Different treatment modalities, therapeutic and prop...
The Efficacy and Safety of Low Dose versus Usual Dose of Hyoscine During Endoscopic Retrograde Cholangiopancreatography: A Randomized Clinical Trial [0.03%]
低剂量与常规剂量的阿托品在内镜逆行胰胆管造影中的有效性和安全性：随机临床试验
Hassan Salmanroghani,Massoud Mirvakili,Mahtabalsadat Mirjalili et al.
Hassan Salmanroghani et al.
Purpose: To evaluate the efficacy and safety of low dose versus usual dose of Hyoscine during endoscopic retrograde cholangiopancreatography (ERCP). Patie...
Dose Regimen Rationale for Panitumumab in Cancer Patients: To Be Based on Body Weight or Not [0.03%]
癌症患者使用Panitumumab的给药方案理由：应基于体重还是不用基于体重
Michael Z Liao,Marloes Berkhout,Hans Prenen et al.
Michael Z Liao et al.
Introduction: Body weight can affect exposure, safety and efficacy of antibody-based therapies; sometimes these effects may not be clinically relevant. Panitumumab is approved for wild-type RAS metastatic colorectal cance...
Inhibitors of the Autotaxin-Lysophosphatidic Acid Axis and Their Potential in the Treatment of Interstitial Lung Disease: Current Perspectives [0.03%]
自分泌运动因子 lysophosphatidic 酸轴抑制剂及其在治疗间质性肺疾病中的潜在应用：当前展望
Sabrina Zulfikar,Sarah Mulholland,Huzaifa Adamali et al.
Sabrina Zulfikar et al.
Idiopathic pulmonary fibrosis is a progressive fibrosing interstitial lung disease for which there is no known cure. Currently available therapeutic options have been shown at best to slow the progression of the disease and thus there remai...
Pharmacokinetic Disposition Difference Between Cyclosporine and Voclosporin Drives Their Distinct Efficacy and Safety Profiles in Clinical Studies [0.03%]
环孢素与沃可昔普仑的药代动力学差异决定了其临床疗效和安全性的不同特点
Yan Li,Maria Palmisano,Duxin Sun et al.
Yan Li et al.
Background: Voclosporin, a more potent derivative of cyclosporine, has been studied extensively in patients with immunologic disorders such as psoriasis, organ transplantation, uvetitis and lupus nephritis. Although bette...
Phytochemical and Antiulcer Activity Screening of Seed Extract of Cordia africana Lam (Boraginaceae) in Pyloric Ligated Rats [0.03%]
塞舌尔非洲 Cordia african 种子提取物的植物化学和抗溃疡作用筛查
Yazachew Engida Yismaw,Mohammedbrhan Abdelwuhab,Digambar B Ambikar et al.
Yazachew Engida Yismaw et al.
Introduction: Peptic ulcer disease represents a worldwide health problem because of its high morbidity, mortality and economic loss. It is a very prevalent condition affecting around 10%-15% of the general population worl...
Clinical Efficacy of Transurethral Resection of the Prostate Combined with Oral Anticholinergics or Botulinum Toxin - A Injection to Treat Benign Prostatic Hyperplasia with Overactive Bladder: A Case-Control Study [0.03%]
经尿道前列腺电切术联合抗胆碱能药物或肉毒杆菌毒素A治疗良性前列腺增生伴膀胱过度活动症的临床疗效：病例对照研究
Farzad Allameh,Abbas Basiri,Mohammadreza Razzaghi et al.
Farzad Allameh et al.
Introduction: Recent investigations showed that anticholinergic drugs could use for the management of storage symptoms after transurethral resection of the prostate (TURP). The use of intravesical botulinum toxin-A (BTX-A...
Overexpression of Adiponectin Receptors in Opium Users with and without Cancer [0.03%]
阿片类药物使用者中肿瘤患者和非肿瘤患者的脂肪细胞因子受体过度表达
Negar Firouzabadi,Maral Haghnegahdar,Bahman Khalvati et al.
Negar Firouzabadi et al.
Aim: Opium addiction is a serious public health concern in the Middle East countries causing various illnesses. Opium use is associated with an increased risk of several cancers; however, the underlying mechanisms are not...
Biomarkers of IL-33 and sST2 and Lack of Association with Carvedilol Therapy in Heart Failure [0.03%]
心力衰竭中白细胞介素33和soluable ST2标志物与卡维地洛治疗无关
Negar Firouzabadi,Maryam Dashti,Ali Dehshahri et al.
Negar Firouzabadi et al.
Objective: The IL-33/ST2 pathway plays a fundamental role in the cardiovascular system and can be considered as a new therapeutic strategy for the treatment or prevention of cardiovascular diseases. ST2, as an interleukin...