Association of a CCB-Related Pharmacogenomics-Guided Strategy with Blood Pressure Outcomes and Short-Term Safety in Chinese Patients with Hypertension: A Secondary Exploratory Analysis of Two Randomized Cohorts [0.03%]
基于CCB药物基因组学指导的高血压患者降压治疗方案在中国患者的血压达标及短期安全性分析：一项探索性研究
Kunhong Deng,Yan Guo,Yaxin Zhang et al.
Kunhong Deng et al.
Introduction: Calcium channel blockers (CCBs) show notable interindividual variability in antihypertensive response. This study evaluated the association of a pharmacogenomics (PGx)-guided antihypertensive strategy incorp...
Design and Evaluation of a Gamification-Based Mobile Application for Reporting Adverse Drug Reactions by Patients and Healthcare Professionals: A Pilot Usability Study in Diabetes Care [0.03%]
基于游戏机制的移动应用的设计与评估：用于患者和医护人员报告不良药物反应并在糖尿病护理中进行试点可用性研究
Kimia Mahini,Rezvan Rahimi,Zohreh Vanaki
Kimia Mahini
Background: Adverse drug reactions (ADRs) represent a significant challenge in pharmacovigilance, particularly for patients with chronic conditions like diabetes. Traditional reporting methods are often cumbersome and suf...
Seasonal Variation in Reporting of Venous Thromboembolism in a Spontaneous Adverse Event Reporting System: Analysis of the Japanese Adverse Drug Event Report Database [0.03%]
日本自主性不良事件报告系统静脉血栓栓塞症的季节性差异：基于日本药品不良反应事件报告数据库的分析
Hiroyuki Tanaka,Toshihiro Ishii
Hiroyuki Tanaka
Background: Venous thromboembolism (VTE) is a major cardiovascular disorder associated with high morbidity and mortality. Several epidemiological studies have reported seasonal variations in VTE, with higher rates during ...
Quality and Timeliness of Pharmacovigilance Reporting in Malawi: A Cross-Sectional Analysis of Individual Case Safety Reports [0.03%]
马拉维药物警戒报告的质量和及时性：个别病例安全报告的横断面分析
Francis Kachidza Chiumia,Frider T Chimimba,Evans Chimayi Chirambo et al.
Francis Kachidza Chiumia et al.
Background: Adverse events related to use of medicinal products are among the significant causes of morbidity and mortality. Quality of adverse event reports is essential for safety risk management. We therefore analyzed ...
Metoclopramide and Risk of Pheochromocytoma Crisis: A Causality Assessment Using Literature and VigiBase Data [0.03%]
甲氧氯普胺与副交感神经瘤危象风险增加的相关性：一项基于文献和VigiBase数据库的因果关系评估研究
Merhawi Bahta,Abraham Dawit,Million Okubazghi et al.
Merhawi Bahta et al.
Introduction: The association between metoclopramide and pheochromocytoma crisis has been documented in literature. However, evidence has primarily relied on case reports and small-scale experimental studies rather than r...
Paracetamol Overdose in Somali Children Under Five: An Emerging Public Health Concern [0.03%]
索马里五岁以下儿童过量服用对乙酰氨基酚：一个新兴的公共卫生问题
Widad Mohamed Hassan
Widad Mohamed Hassan
Paracetamol (acetaminophen) is widely used for pain and fever management in children under five; however, accidental overdose is an increasing public health concern in low-resource settings such as Somalia. This narrative review highlights ...
Trends and Outcomes of Naloxone Use for Iatrogenic Opioid Overdose in Patients on General Wards in a Swiss Hospital: A Ten-Year Retrospective Case Series Analysis [0.03%]
瑞士一家医院普通病房因医源性阿片类药物过量使用纳洛酮的趋势和结局：十年回顾性病例系列分析
Maurice Würsten,Carla Meyer-Massetti,Anne Leuppi-Taegtmeyer et al.
Maurice Würsten et al.
Introduction: Opioids carry an inherent high risk of adverse drug events (ADEs), although these are generally predictable and avoidable through proper management and monitoring. Naloxone, an opioid antagonist, is used to ...
Computed Tomography Diagnostic Reference Levels Worldwide and in Jordan: Implications for Patient Dose Reduction [0.03%]
全球及约旦的CT诊断参考水平及其对降低患者剂量的影响
Ammar A Oglat,Suhaib Shdaifat,Mohannad Adel Sayah et al.
Ammar A Oglat et al.
Computed tomography (CT) contributes substantially to medical radiation exposure, making diagnostic reference levels (DRLs) essential for dose optimization and patient protection. This narrative review summarizes international CT DRL practi...
Exosome Therapy for Livedoid Vasculitis Following COVID-19 Vaccination: A Case Report [0.03%]
新型冠状病毒疫苗接种后 livedoid 血管炎的外泌体治疗——一例报告
Tsung-Kun Lin,Chih-Feng Chang,Gwo-Ping Jong
Tsung-Kun Lin
Livedoid vasculitis is a vascular autoimmune disorder affecting the skin. It most commonly occurs in young women. The occurrence of this condition after the coronavirus 2019 (COVID-19) vaccination is rare. The available literature suggests ...