Facilitators and Barriers to Cervical Cancer Screening Among Women in a Rural District of Northeastern Uganda, a Qualitative Study [0.03%]
乌干达东北部农村地区妇女宫颈癌筛查促进因素和障碍的定性研究
Ibra Mutyaba,Hellen Akurut,Racheal Nabaasa et al.
Ibra Mutyaba et al.
Introduction: Cervical cancer screening in Uganda has remained relatively low, with fewer than one in 10 of eligible women screened, despite the availability of cervical cancer screening services in most health facilities...
Efficacy and Safety of Thermosensitive Hydrogel Combined with Pirarubicin via TACE for Hepatocellular Carcinoma: A Pilot Study [0.03%]
载吡柔比星热敏脂质体结合TACE治疗原发性肝癌的疗效及安全性研究：一项前瞻性临床试验
Chang Liu,Qihui Hu,Baoyong Zhou et al.
Chang Liu et al.
Aim: This pilot study aims to evaluate the technical feasibility, safety profile, and preliminary efficacy of Tepoxin, a thermosensitive hydrogel, combined with pirarubicin via transarterial chemoembolization (TACE) in pa...
Perioperative FLOT versus Definitive 50.4 Gy Chemoradiotherapy in Siewert II Esophagogastric Junction Adenocarcinoma: A Multicenter Retrospective Cohort Study [0.03%]
SiewertⅡ型食管胃结合部腺癌新辅助FLOT与根治性同步放化疗的多中心回顾性队列研究
Sermin Dinc Sonusen,Zehra Sucuoglu Isleyen,Okan Aydin et al.
Sermin Dinc Sonusen et al.
Background: Optimal multimodal treatment for esophagogastric junction adenocarcinoma remains debated. While the ESOPEC trial supports perioperative FLOT, real-world evidence is limited, particularly for Siewert type II tu...
Oncolytic Vaccinia Virus-Engineered EVs Convert Tumor-Promoting Macrophages into Anti-Tumor Effectors [0.03%]
溶瘤天坛病毒工程EV可将肿瘤促进型巨噬细胞转化为抗肿瘤效应细胞
Liqiong Chen,Luyi Ye,Liuqian Bao et al.
Liqiong Chen et al.
Introduction: Extracellular vesicles (EVs) play a critical role in shaping the tumor immune microenvironment (TME) by mediating intercellular communication and transferring oncogenic proteins, microRNAs, and immunosuppres...
Digital Health in Pediatric Oncology and Hematooncology: A Quasi-Systematic Review of Telehealth, mHealth and Precision Medicine [0.03%]
儿科肿瘤学和血液肿瘤学中的数字健康：远程医疗、移动医疗和精准医学的准系统评价
Karolina Joanna Ziętara,Piotr Pawłowski,Natalia Zaj et al.
Karolina Joanna Ziętara et al.
Pediatric oncological and hematological diseases remain a significant challenge due to their complexity, the need for personalized treatment, and long-term follow-up. Recent advances in medical technologies, particularly in information tech...
Inflammatory and Nutritional Biomarkers Predict Response to Neoadjuvant Dual Anti-HER2 Therapy in HER2-Positive Breast Cancer: A Retrospective Cohort Study [0.03%]
炎症和营养生物标志物可预测赫尔辛基乳腺癌患者新辅助双重抗HER2治疗的疗效：回顾性队列研究
Hayriye Şahinli,Galip Can Uyar,Enes Yeşilbaş
Hayriye Şahinli
Purpose: Predicting response to neoadjuvant therapy (NAT) remains a clinical challenge in patients with HER2-positive breast cancer (BC). Systemic inflammatory and immune-nutritional biomarkers have emerged as potential p...
Regorafenib-Induced Stress Response Alters the Bioenergetic Profile of Osteosarcoma Cells and Modulates Gene Expression Associated with Metabolic regulation-a Potential Mechanism of Osteosarcoma Treatment-Related Adaptation [0.03%]
瑞戈非尼诱导的应激反应改变成骨细胞的能量代谢谱并调节与代谢调控相关的基因表达-可能是一种成骨细胞瘤治疗相关适应的潜在机制
Klaudia Marcinkowska,Anna Raciborska,Bożena Obmińska-Mrukowicz et al.
Klaudia Marcinkowska et al.
Purpose: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Despite advances in surgery and multiagent chemotherapy, outcomes remain poor for patients with metastatic or recurrent di...
The Evolving Role of Local Radiotherapy in the Management of Oligometastatic Non-Small Cell Lung Cancer [0.03%]
局灶放射治疗在寡转移非小细胞肺癌管理中的作用变迁
Xiaofei Zhang,Mengzhen Liu,Zhenbo Wang
Xiaofei Zhang
Oligometastasis represents an intermediate stage between locally advanced disease and widespread metastasis, typically referring to stage IV disease with a limited number of metastatic lesions (generally no more than five) and controlled pr...
Context-Dependent Dual Roles of the Plexin-B Family in Cancer Progression: Mechanisms and Therapeutic Implications [0.03%]
plexin-b家族在癌症进展中的上下文依赖性双重作用：机制和治疗意义
Xiuli Mao,Wenxian Lin,Xiamin Zhang et al.
Xiuli Mao et al.
The Plexin-B family, comprising Plexin-B1, Plexin-B2, and Plexin-B3, represents a class of single-pass transmembrane receptors whose context-dependent functional outputs are governed by six contextual determinants-ligand availability, co-re...
Protocadherin 1 (PCDH1) Promotes Pancreatic Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition (EMT) Progression Through the NF-κB Pathway [0.03%]
原癌基因PCDH1通过NF-κB通路调节上皮间质转化促进胰腺癌转移
JianXin Lv,Jie Lou,Shaoqing Ding et al.
JianXin Lv et al.
Objective: This study investigates the role of the protocadherin-1 (PCDH1) gene in pancreatic cancer metastasis, focusing on its influence on the epithelial-mesenchymal transition (EMT) process and the NF-κB signaling pa...