Regorafenib-Induced Stress Response Alters the Bioenergetic Profile of Osteosarcoma Cells and Modulates Gene Expression Associated with Metabolic regulation-a Potential Mechanism of Osteosarcoma Treatment-Related Adaptation
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Purpose: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. Despite advances in surgery and multiagent chemotherapy, outcomes remain poor for patients with metastatic or recurrent disease. R... ...
