The Clinical Study of Intratumoral and Peritumoral Radiomics Based on DCE-MRI for HER-2 Positive and Low Expression Prediction in Breast Cancer [0.03%]
基于DCE-MRI的乳腺癌肿瘤内和肿瘤周影像组学研究在HER-2阳性及低表达预测中的临床应用价值探讨
Yiyan Shang,Yunxia Wang,Yaxin Guo et al.
Yiyan Shang et al.
Background: Core biopsy sampling may not fully capture tumor heterogeneity. Radiomics provides a non-invasive method to assess tumor characteristics, including both the core and surrounding tissue, with the potential to i...
A Prospective Tumour Marker for Breast Cancer: YWHAB and Its Role in Promoting Oncogenic Phenotypes [0.03%]
乳腺癌的前瞻性肿瘤标志物：YWHAB及其促致癌表型的作用
Vaishnavi L Gopaul,Lacey Winstone,Beatrice G Gatien et al.
Vaishnavi L Gopaul et al.
Background: YWHAB (14-3-3 Beta) was found in the secretome of miR-526b and miR-655 overexpressed breast cancer (BRCA) cell lines. The potential of YWHAB as a therapeutic target or biomarker for BRCA is investigated here. ...
Exploring the Complexity of Pan-Cancer: Gene Convergences and in silico Analyses [0.03%]
探究泛癌症的复杂性：基因趋同与计算机分析
Leandro Teodoro,Ana Claudia O Carreira,Mari C Sogayar
Leandro Teodoro
Cancer is a complex and multifaceted group of diseases characterized by highly intricate mechanisms of tumorigenesis and tumor progression, which complicates diagnosis, prognosis, and treatment. In recent years, targeted therapies have gain...
A Novel Peroxisome-Related Gene Signature Predicts Breast Cancer Prognosis and Correlates with T Cell Suppression [0.03%]
一个新的过氧化物酶体相关基因签名预测乳腺癌预后并与T细胞抑制相关
Yunxiang Wang,Sheng Xu,Junfeng Liu et al.
Yunxiang Wang et al.
Background: Peroxisomes are increasingly linked to cancer development, yet the prognostic role of peroxisome-related genes (PRGs) in breast cancer remains unclear. ...
Comparison of Hematological Parameters and the Associated Factors Among Women with and without Breast Cancer: A Case-Control Study [0.03%]
乳腺癌患者与健康对照组血液学参数及影响因素的对比研究
Abdul Baset Abbas,Shima Al-Gamei,AmatAlraheem Naser et al.
Abdul Baset Abbas et al.
Background: Breast cancer (BC) is the most popular and dangerous cancer, with a high mortality rate. Hematological parameters are often used in routine diagnosis of numerous disorders. Therefore, the study aimed to evalua...
Psychological Stress and Its Correlations to Patients with Acute Lymphedema After Breast Cancer Surgery [0.03%]
急性乳腺癌术后淋巴水肿患者的焦虑抑郁情绪及相关因素分析
Li-Ping Ge,Lichen Tang,WenJia Zuo et al.
Li-Ping Ge et al.
Background: Lymphedema and psychological distress, including anxiety and depression, are common in breast cancer patients post-surgery. This study aimed to assess the incidence and determinants of anxiety and depression i...
Role of Harmaline in Inhibiting c-Myc, Altering Molecular Typing, and Promoting Apoptosis in Triple-Negative Breast Cancer [0.03%]
哈马林通过抑制c-myc、改变分子分型和促进凋亡来对抗三阴性乳腺癌的作用机制研究
Haoyi Xu,Yan Ma,Huiling Li et al.
Haoyi Xu et al.
Objective: Triple-negative breast cancer (TNBC) lacks effective targeted, endocrine therapeutic agents and the development of novel agents is costly and time-consuming. The objective of this study was to identify pharmace...
Feasibility Study of Pyrrolitinib-Based Dual-Target Therapy for Neoadjuvant Treatment of HER2-Positive Breast Cancer Patients [0.03%]
吡咯替尼双靶新辅助治疗阳性乳腺癌患者的可行性研究
Feng Zhao,Hongzhen Zhang
Feng Zhao
Background: HER2-positive breast cancer is one of the high-risk subtypes of breast cancer for which dual-targeted therapy has become an important treatment option. However, for some patients, complete control of the disea...
Dysregulation of Fatty Acid Metabolism in Breast Cancer and Its Targeted Therapy [0.03%]
乳腺癌中脂肪酸代谢紊乱及其靶向治疗
Yue Chang,Rui Du,Fan Xia et al.
Yue Chang et al.
Breast cancer has become the number one cancer worldwide, there are challenges in its prevention, diagnosis and treatment, especially the pathogenesis of triple negative breast cancer has not been clear and the treatment dilemma of metastat...
Identification and Validation of circDOCK1/miR-138-5p/GRB7 Axis for Promoting Breast Cancer Progression [0.03%]
circDOCK1/miR-138-5p/GRB7轴促进乳腺癌进展的鉴定与验证
Yan Zhang,Mei Yang,Yiping Wang et al.
Yan Zhang et al.
Background: Non-coding RNAs have received increasing attention in human tumors, with RNA interaction networks playing important roles in breast cancer. This study aims to explore novel circular RNAs and their mechanisms o...