Min Xiong,Quanjun Yang,Le Cheng et al.
Min Xiong et al.
Objective: To clarify the expression and clinical significance of LINC01128 in triple-negative breast cancer (TNBC), investigate whether it regulates the biological behaviors of TNBC cells by targeting miR-32-5p via the c...
From Axillary Lymph Node Dissection to Sentinel Node Biopsy in Breast Cancer: A 23-Year Population-Based Large-Sample Study with Long-Term Survival Outcomes [0.03%]
Lucia Mangone,Francesco Marinelli,Isabella Bisceglia et al.
Lucia Mangone et al.
Purpose: Axillary surgery in breast cancer has progressively evolved over the past decades toward less invasive approaches. Patients and methods: ...
Capecitabine versus Paclitaxel After CDK4/6 Inhibitor Progression in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Real-World Study [0.03%]
Zeliha Birsin,Ali Kaan Güren,Vali Aliyev et al.
Zeliha Birsin et al.
Background: Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy represent the standard first-line treatment for hormone receptor-positive (HR+), HER2-negative metastatic breast cancer. However...
HER2 Overexpression in Invasive Breast Carcinoma in the Democratic Republic of Congo and its Association with Selected Clinicopathological Characteristics [0.03%]
Guy Ilunga Nday,Manix Ilunga Banza,Anastasie Ngalula Umpungu et al.
Guy Ilunga Nday et al.
Background: Breast cancer is a heterogeneous disease and HER2 overexpression identifies a subgroup of tumors associated with aggressive behavior and targeted therapy response. Although HER2 expression has been widely stud...
Adjuvant Weekly Paclitaxel and Trastuzumab for HER2-Positive Early-Stage Breast Cancer with Preserved Baseline LVEF: Incidence of Cardiotoxicity and Feasibility of Simplified Cardiac Surveillance [0.03%]
Akira Tsunoda,Toshiro Mizuno,Shiro Nakamori et al.
Akira Tsunoda et al.
Purpose: The incidence of trastuzumab-related cardiotoxicity is low among patients receiving regimens that do not include anthracyclines. We aimed to examine whether cardiac monitoring during paclitaxel and trastuzumab th...
Single-Cell Profiling Reveals a Treg-Rich, NK Cell-Depleted Immune Microenvironment in Triple-Negative Breast Cancer with High-Glucocorticoid Receptor Expression [0.03%]
Joshua Behar,Christine Shiang,Deniz Nesli Dolcen et al.
Joshua Behar et al.
Purpose: Analyses of patients with early-stage, treatment-naïve triple-negative breast cancer (TNBC) have demonstrated that high glucocorticoid receptor (GR) expression in primary tumors is associated with poor prognosis...
Bridging Clinical Trials to Real-World Clinical Practice: TCHP Neoadjuvant Therapy Outcomes in HER2-Positive Breast Cancer [0.03%]
Baha Sharaf,Alaa Seif,Hira Bani Hani et al.
Baha Sharaf et al.
Purpose: Trastuzumab-based neoadjuvant therapy (NAT) is standard for HER2-positive breast cancer (HER2+ BC). The TCHP regimen (docetaxel, carboplatin, trastuzumab, pertuzumab) demonstrated efficacy in clinical trials; how...
Analysis of Factors Related to Lymph Node Metastasis Following Neoadjuvant Chemotherapy for Breast Cancer: Correlation Between Plasma Exosomal Circular RNA and Metastasis [0.03%]
Sushuang Ma,Yanqiu Huang,Qingyan Yang et al.
Sushuang Ma et al.
Objective: To investigate the correlation between plasma exosomal circular RNA (circRNA) (non-invasive, dynamically monitorable) and lymph node metastasis following neoadjuvant chemotherapy in breast cancer and highlight ...
IFI44 Orchestrates an IL-10-Driven M2 Macrophage Program in Breast Cancer: An Immune Prognostic Signature [0.03%]
Jiahui Wu,Wang Yi,Mengting Liu et al.
Jiahui Wu et al.
Background: Although IFI44 is recognized for its crucial role in autoimmune disorders, its function in breast cancer (BC) remains unclear. This study aimed to investigate the immune-related and prognostic significance of ...
Supportive Intervention for Unmet Needs Among Breast Cancer Patients and Their Spousal Caregivers: A Randomized Controlled Trial [0.03%]
Qian Zhang,Shan Wang,Jiajia Zhang et al.
Qian Zhang et al.
Purpose: This study aims to evaluate the effectiveness of a supportive intervention program designed based on Existence-Relatedness-Growth theory and the Supportive Care Needs Framework in reducing unmet needs among breas...