Development and Validation of Machine Learning Models in Predicting Prognosis of Breast Cancer Patients with Lymph Nodes Metastasis Following Neoadjuvant Chemotherapy [0.03%]
新辅助化疗后淋巴结转移的乳腺癌患者预后的机器学习模型的研发与验证
Yanjia Fan,Yudi Jin,Cheng Tian et al.
Yanjia Fan et al.
Background: Lymph node (LN) status is a critical prognostic factor for breast cancer patients undergoing neoadjuvant chemotherapy (NAC). This study aims to develop and validate machine learning models to predict LN respon...
Triple-Negative Breast Cancer on the Rise: Breakthroughs and Beyond [Response to Letter] [0.03%]
三阴性乳腺癌的诊疗进展：突破与展望——回复来信
Alex Agelidis,Anna Ter-Zakarian,Mohammed Jaloudi
Alex Agelidis
Efficacy of Trastuzumab Deruxtecan in HER2-Positive and HER2-Low Metastatic Breast Cancer: A Real-World Retrospective Cohort Study in China [0.03%]
针对HER2阳性及低表达的转移性乳腺癌患者使用DS-8201疗效的真实世界回顾队列研究
Yuxin Yan,Yizi Jin,Mingxi Lin et al.
Yuxin Yan et al.
Background: Limited real-world data are available on the effectiveness and safety of trastuzumab deruxtecan (T-DXd, DS8201a) in patients with HER2-positive and HER2-low metastatic breast cancer (MBC), particularly within ...
Clinical Management of Circulating Tumor DNA in Breast Cancer: Detection, Prediction, and Monitoring [0.03%]
循环肿瘤DNA在乳腺癌临床管理中的应用：检测、预测与监测
Yongqu Lu,Lehao Ren,Meng Yang et al.
Yongqu Lu et al.
Despite substantial progress in the diagnosis and treatment of breast cancer, current therapeutic regimens exhibit limitations, necessitating the identification of more robust biomarkers to optimize personalized strategies. Circulating tumo...
Per Eystein Lønning,Oleksii Nikolaienko,Stian Knappskog
Per Eystein Lønning
ANXA2 Regulates RANKL-Induced Osteoclast Differentiation Through STAT3 Signaling in Breast Cancer [0.03%]
乳腺癌中ANXA2通过STAT3信号调节RANKL诱导的破骨细胞分化
Jie Yuan,Fei Xin,Ruliang Wang
Jie Yuan
Background: Bone metastasis affects nearly 70% of patients with advanced breast cancer, significantly influencing patient survival. Osteoclasts play a crucial role in osteolysis and the proliferation of bone tumor cell me...
Effects of Clinacanthus nutans Extracts on Cell Proliferation and Apoptosis in Triple-Negative Breast Cancer: Mechanistic Insights [0.03%]
Clinacanthus nutans提取物对三阴性乳腺癌细胞增殖和凋亡的影响：机制见解
Jiafang Xu,Jincha Long,Zhen Ying Li et al.
Jiafang Xu et al.
Objective: To explore the effects of Clinacanthus nutans extract (CnE) on triple-negative breast cancer (TNBC) and mechanism of action. Methods: ...
Utility of Volatile Organic Compounds and Electronic Nose Technology for Breast Cancer Detection: A Systematic Review [0.03%]
挥发性有机化合物和电子鼻技术在乳腺癌检测中的应用价值：系统综述
Fernanda M Orduña-Medina,Lorena Díaz de León-Martinez,Grecia D D Alarcón-Rivera et al.
Fernanda M Orduña-Medina et al.
Breast cancer is a leading cause of mortality in women worldwide, primarily due to challenges in early detection and limited access to timely treatment. While mammography is widely used, it may produce false positives and lead to overdiagno...
The Role of The Xihuang Pill in Inhibiting Triple-Negative Breast Cancer Through Immunogenic Cell Death [0.03%]
消癌解毒方通过免疫原性细胞死亡抑制三阴性乳腺癌的作用研究
Xingchao Xu,XiangQi Li
Xingchao Xu
Modern Western medicine uses surgeries, chemotherapy, targeted therapy, and radiotherapy to inhibit breast cancer cells through pathways such as apoptosis, necrosis, and autophagy. However, for triple-negative breast cancer (TNBC), a highly...
Investigation of Thrombocytopenia Associated with Trastuzumab Emtansine Treatment in Breast Cancer: A Retrospective Study in a Chinese Population [0.03%]
曲妥珠单抗-美坦辛治疗相关的血小板减少症在中国乳腺癌患者中回顾性研究
Kun Zhang,Shijie Wu,Yunxiang Zhou et al.
Kun Zhang et al.
Purpose: Thrombocytopenia is a common adverse event associated with trastuzumab emtansine (T-DM1) treatment in patients with HER2-positive metastatic breast cancer. This study aims to evaluate the incidence, clinical char...