Adipokines in Breast Cancer: Decoding Genetic and Proteomic Mechanisms Underlying Migration, Invasion, and Proliferation [0.03%]
乳腺癌中的脂肪细胞因子：解码迁移、侵袭和增殖的遗传和蛋白组学机制
Anne Ließem,Uwe Leimer,Günter K Germann et al.
Anne Ließem et al.
Background: Adipokines, bioactive peptides secreted by adipose tissue, appear to contribute to breast cancer development and progression. While numerous studies suggest their role in promoting tumor growth, the exact mech...
Non-Luminal Disease Score for Everolimus in Patients with Hormone Receptor‑positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Multicenter and Retrospective Study [0.03%]
依维莫司治疗激素受体阳性人表皮生长因子受体2阴性晚期乳腺癌患者的非瘤腔病变评分：一项多中心回顾性研究
Yujing Tan,Hanfang Jiang,Xinzhu Tian et al.
Yujing Tan et al.
Purpose: This study aims to explore the role of the non-luminal disease score (NOLUS) for everolimus in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced br...
From Pioneering Discoveries to Innovative Therapies: A Journey Through the History and Advancements of Nanoparticles in Breast Cancer Treatment [0.03%]
从开创性发现到创新疗法：纳米颗粒在乳腺癌治疗中的历史与发展之旅
Fatemah S Basingab,Omniah A Alshahrani,Ibtehal H Alansari et al.
Fatemah S Basingab et al.
Nanoparticle technology has revolutionized breast cancer treatment by offering innovative solutions addressing the gaps in traditional treatment methods. This paper aimed to comprehensively explore the historical journey and advancements of...
Lorenzo Belluzzi,Giulio Martinelli,Bianca Medici et al.
Lorenzo Belluzzi et al.
In recent years, new anticancer drugs have been investigated and approved for the treatment of breast cancer based on improved survival outcomes. However, these new treatments have specific class-related side effects. Pulmonary toxicity has...
Functional Analysis and Experimental Validation of the Prognostic and Immune Effects of the Oncogenic Protein CDC45 in Breast Cancer [0.03%]
CDC45致癌蛋白在乳腺癌预后及免疫中的功能分析和实验验证
Jia-Ning Zhang,Lin-Wei Li,Man-Qing Cao et al.
Jia-Ning Zhang et al.
Purpose: Cell division cycle protein 45 (CDC45) plays a crucial role in DNA replication. This study investigates its role in breast cancer (BC) and its impact on tumor progression. ...
Optimizing Xenograft Models for Breast Cancer: A Comparative Analysis of Cell-Derived and Patient-Derived Implantation Techniques in Pre-Clinical Research [0.03%]
优化乳腺癌异种移植模型：前临床研究中细胞源性和患者源性植入技术的比较分析
Astrid Feinisa Khairani,Shella Harmonia,Yoan Chou et al.
Astrid Feinisa Khairani et al.
Purpose: The high mortality rate of breast cancer motivates researchers to search for effective treatments. Due to their ability to simulate human conditions, xenograft models such as CDX (Cell line-Derived Xenografts) an...
Correlation of Histopathological and Radiological Response Patterns and Their Prognostic Implications in Breast Cancer After Neoadjuvant Chemotherapy [0.03%]
新辅助化疗后乳腺癌的病理和影像学应答模式及其预后的相关性研究
Ahmet Bozer,Cengiz Yilmaz,Hülya Çetin Tunçez et al.
Ahmet Bozer et al.
Purpose: In breast cancer (BC), neoadjuvant chemotherapy (NAC) responses can be categorized as concentric shrinkage (CS), non-concentric shrinkage (non-CS), and complete response, influencing surgical planning and surviva...
Quercetin Promote the Chemosensitivity in Organoids Derived from Patients with Breast Cancer [0.03%]
檞皮素可通过乳腺癌来源类器官的WNT信号促进化疗增敏作用
Shengwen Meng,Yifan Cao,Lei Lu et al.
Shengwen Meng et al.
Aim: The study aimed to culture organoids from tissues of patients with breast cancer (BC) and use the organoids to measure the sensitivity to quercetin and its combination with chemotherapeutic agents. ...
Preoperative Prediction of Breast Cancer Histological Grade Using Intratumoral and Peritumoral Radiomics Features from T2WI and DWI MR Sequences [0.03%]
基于T2WI和DWI序列影像组学特征的乳腺癌组织学分级术前预测模型研究
Yaxin Guo,Jun Liao,Shunian Li et al.
Yaxin Guo et al.
Background: Histological grade is an acknowledged prognostic factor for breast cancer, essential for determining clinical treatment strategies and prognosis assessment. Our study aims to establish intra- and peritumoral r...
Frank E Gump,Priyanka Parmar,Sheldon Feldman et al.
Frank E Gump et al.
Early detection is a relative newcomer in medicine, with its efficacy relying not only on therapy but also on the availability of evidence supporting the advantage of treatment at an earlier stage. Late 19th century histologic evidence that...