A Machine-Learning Model for the Prediction of Triple-Negative Breast Cancer Based on Multiparameter MRI [0.03%]
基于多参数MRI的三阴性乳腺癌预测机器学习模型
Yuxin Cai,Yanbo Li,Wenqi Wang et al.
Yuxin Cai et al.
Objective: To explore the difference between triple-negative breast cancer (TNBC) and non-triple-negative breast cancer (non-TNBC) based on multi-parametric MRI imaging features and construct a prediction model to identif...
Simultaneous Implant and Dermal Flap Technique for Breast Reconstruction After Skin-Sparing Total Mastectomy for Breast Carcinoma [0.03%]
乳房癌保留皮肤的全乳腺切除术后即刻带真皮皮瓣的假体植入乳房再造术
Özgür Agdoğan,Sibel Gürdal Özkan
Özgür Agdoğan
Objective: This study aims to evaluate the simultaneous implant and dermal flap technique for breast reconstruction following skin-sparing total mastectomy in breast carcinoma patients, assessing both oncological and aest...
Exploring the Mechanism of Lianqiao Jinbei Decoction Inhibiting HER2-Positive Breast Cancer Based on Network Pharmacology and Experimental Verification [0.03%]
基于网络药理学和实验验证的连翘金贝汤抗HER2阳性乳腺癌机制研究
Dehui Li,Xukuo Liu,Huanfang Fan et al.
Dehui Li et al.
Purpose: Through network pharmacological prediction and in vitro experimental verification, the mechanism of action of Lianqiao Jinbei Decoction (LJD) in inhibiting HER2-positive breast cancer cells was clarified, providi...
Heterogeneity Assessment of Breast Cancer Tumor Microenvironment: Multiparametric Quantitative Analysis with DCE-MRI and Discovery of Radiomics Biomarkers [0.03%]
乳腺癌肿瘤微环境的异质性评估:DCE-MRI的多参数定量分析及影像组学生物标志物的发现
Wenhui Ma,Lu Yang,Yu Zhang et al.
Wenhui Ma et al.
The heterogeneity of the tumor microenvironment (TME) in breast cancer significantly influences therapeutic response and prognosis, yet noninvasive evaluation remains a clinical challenge. Dynamic contrast-enhanced magnetic resonance imagin...
Male Breast Cancer: Evaluating the Current Landscape of Diagnosis and Treatment [0.03%]
男性乳腺癌:评估当前诊断和治疗的格局
Anna Ter-Zakarian,Alex Agelidis,Mohammed Jaloudi
Anna Ter-Zakarian
Male breast cancer (MBC) is a rare condition, comprising less than 1% of all breast cancer cases. This review examines the epidemiology, risk factors, clinical presentation, diagnostic approaches, and treatment strategies for MBC in both ea...
Advancements in Dalpiciclib for the Treatment of Breast Cancer Patients: A Review [0.03%]
达尔匹西利治疗乳腺癌患者的进展:综述
Zhimin Chen,Pengjun Xie,Qihai Chen et al.
Zhimin Chen et al.
Combining cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6 inhibitors) with cyclin-dependent proteins can reduce the formation of cyclin D-CDK4/6 complexes, resulting in the inactivation of downstream genes and suppression of cell prolife...
Continuous Anlotinib Combined with Oral Vinorelbine has Shown Anti-Tumor Efficiency in Refractory HER2 Negative Advanced Breast Cancer [0.03%]
阿尼鲁单抗联合口服长春瑞滨治疗难治性HER2阴性晚期乳腺癌的疗效及安全性研究
Jia-Yi Huang,Yan Zhang,Cai-Wen Du
Jia-Yi Huang
Purpose: To explore the efficacy and safety of continuous administration of anlotinib combined with oral vinorelbine in refractory human epidermal growth factor-2 (HER2) negative advanced breast cancer (ABC). ...
Current Strategies to Reducing Interval Breast Cancers: A Systematic Review [0.03%]
缩短乳腺癌筛查间隔以减少 interval breast cancer 的策略系统评价
Rachel Sze Jen Goh,Bryan Chong,Selvie Yeo et al.
Rachel Sze Jen Goh et al.
Background: Interval breast cancers (IBCs) are detected between regular mammographic screenings after an initially negative result. Studies have shown that the prognosis of IBCs is similar to that of unscreened symptomati...
Alex Agelidis,Anna Ter-Zakarian,Mohammed Jaloudi
Alex Agelidis
Triple-negative breast cancer (TNBC) represents a particularly aggressive and heterogeneous subtype of breast cancer, associated with poor prognosis and limited treatment options. This review delves into the rising incidence of TNBC, partic...
Research Progress of PROTAC-Degraded CDKs in the Treatment of Breast Cancer [0.03%]
靶向泛素蛋白酶体系统的PROTAC降解CDKs治疗乳腺癌的研究进展
Kexin Zhao,Jun Zhang,Zhe Yang et al.
Kexin Zhao et al.
Breast cancer (BC) is the most common type of cancer among women worldwide. A large number of studies have found that the high expression or dysregulation of cyclin-dependent protein kinases (CDKs) is closely associated with breast cancer. ...