Preliminary Study on Clinical Characteristics and Pathogenesis of IQSEC2 Mutations Patients [0.03%]
IQSEC2基因突变患者的临床特征和发病机制初探
Yun Ren,Xiaona Luo,Haiyan Tong et al.
Yun Ren et al.
Background: The IQ motif and Sec7 domain ArfGEF 2 (IQSEC2), an X-linked gene that encodes the BRAG1 protein, is a guanine nucleotide exchange factor for the ADP ribosylation factor (ARF) protein family in the small guanos...
16S rRNA Gene Sequencing of Gut Microbiota in Rheumatoid Arthritis Treated with 99Tc-MDP [0.03%]
99Tc-MDP治疗的类风湿关节炎患者肠道菌群的16S rDNA测序分析
Zhaowei Huang,Changming Chen,Linlin Tan et al.
Zhaowei Huang et al.
Background: Rheumatoid arthritis (RA) is a common autoimmune disease with the main symptoms being joint swelling and pain. In severe cases, joint deformity or even complete loss of function occurs. Technetium methylene di...
An Aging-Related lncRNA Signature Establishing for Breast Cancer Prognosis and Immunotherapy Responsiveness Prediction [0.03%]
基于乳腺癌预后和免疫治疗反应预测的与衰老相关的长链非编码RNA标志物的建立
Yanshijing Zhou,Zihui Yang,Hong Zeng
Yanshijing Zhou
Purpose: Emerging evidence demonstrates the vital role of aging and long non-coding RNAs (lncRNAs) in breast cancer (BC) progression. Our study intended to develop a prognostic risk model based on aging-related lncRNAs (A...
To Investigate the Influence of Smoking Cessation Intention and Common Downstream Variants of HDAC9 Gene on Large Artery Atherosclerotic Cerebral Infarction [0.03%]
吸烟戒断意愿和组蛋白去乙酰化酶9基因常见下游变异对大动脉粥样硬化性脑梗死的影响研究
Lili Yu,Youwei Zhao
Lili Yu
Objective: To investigate the association of smoking cessation intention and single nucleotide polymorphism of HDAC9 gene with LAA-S in Han people in Hainan province. ...
Evaluation of CYP2C19 Genetic Variant and Its Lack of Association with Valproic Acid Plasma Concentrations Among Zhuang and Han Schizophrenia Patients in Guangxi [0.03%]
评估CYP2C19基因多态性及其与广西壮族和汉族精神分裂症患者丙戊酸血药浓度缺乏关联性研究
Jun Mei Teng,Shuiqing Qin,Danyu Lu et al.
Jun Mei Teng et al.
Purpose: To investigate the CYP2C19 genotype distribution and allelic frequency among the Zhuang and Han schizophrenic populations in Guangxi, examine the correlation between CYP2C19 genetic variants and standardized bloo...
Understanding Gene Involvement in Hepatocellular Carcinoma: Implications for Gene Therapy and Personalized Medicine [0.03%]
肝细胞癌的基因参与研究：基因治疗和个体化医疗的启示
Mahmoud A Younis,Hideyoshi Harashima
Mahmoud A Younis
Hepatocellular carcinoma (HCC) is the dominant type of liver cancers and is one of the deadliest health threats globally. The conventional therapeutic options for HCC are hampered by low efficiency and intolerable side effects. Gene therapy...
Association of the Reduced Function Met420del Polymorphism of SLC22A1 with Metformin-Induced Gastrointestinal Intolerance in Ethiopian Patients with Type 2 Diabetes Mellitus [0.03%]
SLC22A1基因Met420del多态性与埃塞俄比亚2型糖尿病患者二甲双胍相关胃肠道不良反应的关联研究
Abraham Degaga,Sisay Sirgu,Hasniza Zaman Huri et al.
Abraham Degaga et al.
Background: Despite its widespread use and favored profile, there are extensive variations in the treatment outcome of metformin therapy. Furthermore, studies reported that the inter-individual variability in the occurren...
Three Liquid-Liquid Phase Separation-Related Genes Associated with Prognosis in Glioma [0.03%]
与胶质瘤预后相关的三个液-液相分离相关基因
Ling Lv,Xin Zhang,Yajun Liu et al.
Ling Lv et al.
Purpose: Dysregulated liquid-liquid phase separation (LLPS) instigates tumorigenesis through biomolecular condensate dysfunction. However, the association between LLPS-associated genes and glioma remains underexplored. ...
ACE Gene Mutations (rs577350502) in Early-Onset and Recurrent Myocardial Infarction: A Case Report and Review [0.03%]
血管紧张素转换酶基因突变（rs577350502）导致的早发性和复发性心肌梗死：1例报告及文献复习
Xiaoxi Deng,Xiaofei Guo,Xiaojie Chen et al.
Xiaoxi Deng et al.
Background: Acute myocardial infarction (AMI) is a severe acute coronary syndrome, demonstrating a trend toward affecting younger individuals in recent years. The association between early-onset myocardial infarction and ...
Downregulation of NAT1 Expression is Associated with Poor Prognosis and Immune Infiltration in COAD [0.03%]
NAT1表达下调与结肠直肠腺癌不良预后和免疫浸润相关
Houxi Xu,Hongqun Zhang,Songxian Sun et al.
Houxi Xu et al.
Background: An increasing corpus of evidence has identified the involvement of N-acetyltransferase 1 (NAT1), a member of the NAT family, in the progression of various cancers. However, the specific function of NAT1 in col...