PEAR1, PON1, CYP2C19, CYP1A2 and F2R Polymorphisms are Associated with MACE in Clopidogrel-Treated Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention [0.03%]
在急诊经皮冠状动脉介入治疗中的急性冠脉综合症患者中，卡普西普治疗与PEAR1、PON1、CYP2C19、CYP1A2和F2R多态性相关联的MACE风险
Pengqiang Du,Xingang Li,Dandan Li et al.
Pengqiang Du et al.
Objective: The objective of this study was to evaluate the impact of clopidogrel-related gene polymorphisms on the occurrence of recurrent thrombotic events and cardiovascular death in patients with acute coronary syndrom...
Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidemia [0.03%]
载脂蛋白编码区SLCO1B1多态性与汉族高血脂成人阿托伐他汀治疗前后的血清脂联素水平变化及其相关性的研究
Chao Chen,Yan Tian,Fengshun Jia et al.
Chao Chen et al.
Purpose: Atorvastatin is commonly used to treat dyslipidemia; however, individual responses vary considerably. This study endeavors to evaluate the relationship between polymorphisms in the coding sequence (CDS) of SLCO1B...
CD27 as a Diagnostic Biomarker and Its Role in Immune Heterogeneity and Predicting Clinical Drug Responses in Hashimoto's Thyroiditis [0.03%]
CD27作为诊断生物标志物及其在Hashimoto甲状腺炎免疫异质性和预测临床药物反应中的作用
Yan-Ming Dong,Guo-Qiang Bao
Yan-Ming Dong
Objective: To identify key genes and potential molecular mechanisms associated with Hashimoto's thyroiditis (HT) to provide new insights for the development of diagnostic and therapeutic targets for this disease. ...
Prognostic Value and Immunological Role of POP7 in Clear Cell Renal Cell Carcinoma [0.03%]
POP7在透明细胞肾细胞癌中的预后价值和免疫学作用
Ning Lou,Xiangui Meng,Tiexi Yu et al.
Ning Lou et al.
Background: Studies have found that RNA-binding proteins (RBPs) are participated in the occurrence or development of tumours. However, the role of processing of precursor family (POP family) in clear cell renal cell carci...
Immune Microenvironment Alterations and Identification of Key Diagnostic Biomarkers in Chronic Kidney Disease Using Integrated Bioinformatics and Machine Learning [0.03%]
整合生物信息学和机器学习识别慢性肾脏疾病免疫微环境改变及关键诊断生物标志物
Jinbao Shi,Aliang Xu,Liuying Huang et al.
Jinbao Shi et al.
Background: Chronic kidney disease (CKD) involves complex immune dysregulation and altered gene expression profiles. This study investigates immune cell infiltration, differential gene expression, and pathway enrichment i...
Hsa_circ_0078767 Enhances Osteosarcoma Chemoresistance to Doxorubicin Through the Regulation of the miR-188-3p/GPX4 Axis [0.03%]
Hsa_circ_0078767通过调节miR-188-3p/GPX4轴增强骨肉瘤对多柔比星的耐药性
Yin Tang,Yuzhe He,Lidong Wu
Yin Tang
Background: Osteosarcoma (OS) is a primary malignancy of bone. The emergence of chemoresistance represents a persistent barrier to effective cancer patient care. This analysis sought to examine hsa_circ_0078767 as a media...
Genetic Diversity Landscape in African Population: A Review of Implications for Personalized and Precision Medicine [0.03%]
非洲人群基因多样性格局及对精准医疗的意义
Olivier Sibomana
Olivier Sibomana
Introduction: Africa, a continent considered to be the cradle of human beings has the largest genetic diversity among its population than other continents. This review discusses the implications of this high African genet...
Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension [0.03%]
高血压患者氨氯地平降压反应的药理基因组研究
Asif Jan,Abdullah R Alanzi,Ramzi A Mothana et al.
Asif Jan et al.
Introduction: Despite the availability of various antihypertensive medications, the response to these medications varies among individuals. Understanding how individual genetic variations affect drugs treatment outcomes i...
Bioinformatics-Based Identification of Key Prognostic Genes in Neuroblastoma with a Focus on Immune Cell Infiltration and Diagnostic Potential of VGF [0.03%]
基于生物信息学的神经母细胞瘤关键预后基因鉴定及VGF基因免疫细胞浸润和诊断潜能分析
Qiang Guo,Yang Xiao,Jing Chu et al.
Qiang Guo et al.
Objective: This study aims to identify differentially expressed genes (DEGs) in neuroblastoma (NB) through comprehensive bioinformatics analysis and machine learning techniques. We seek to elucidate these DEGs' biological...
Serum IFN-γ Predicts the Therapeutic Effect of Belimumab in Refractory Lupus Nephritis Patients [0.03%]
基线血清IFN-γ预测贝尔单抗治疗难治性狼疮肾炎患者的疗效
Shanshan Liu,Ju Li,Zhongyuan Zhang et al.
Shanshan Liu et al.
Objective: To evaluate belimumabf's efficacy in refractory lupus nephritis (LN) patients and identify predictive serum biomarkers for treatment response. ...