Exploring Clinical Characteristics and Risk Factors of Mycoplasma pneumoniae-Induced Segmental/Lobar Pneumonia in Chongqing, China, During 2023: A Single-Center Retrospective Cohort Study of Hospitalized Children [0.03%]
中国重庆市2023年儿童住院患者肺炎支原体所致节段性/肺叶性肺炎的临床特点和危险因素：一项单中心回顾性队列研究
Yaozheng Ling,Yu Zhao,Chenghao Mei et al.
Yaozheng Ling et al.
Purpose: Mycoplasma pneumoniae (MP)-segmental/lobar pneumonia represents a growing proportion of Mycoplasma pneumoniae pneumonia (MPP) in children. We aimed to identify the clinical characteristics and risk factors for MP...
Endoscopic Retroperitoneal Debridement Combined with Posterior Percutaneous Pedicle Screw Fixation for Lumbar Infectious Spondylodiscitis: A Retrospective Study and Preliminary Results [0.03%]
内镜下腰椎后路窦道清除联合经皮螺钉固定治疗腰椎感染性脊柱炎的初步研究
Yongrui Yang,Wenkai Ruan,Jianlong Li et al.
Yongrui Yang et al.
Background: Lumbar infectious spondylodiscitis is a severe spinal condition traditionally managed with antibiotics, though some patients require surgical intervention. The heterogeneity in infection sites, causative patho...
Effects of Hypoglycemic Agents on Pulmonary Diseases: A Comprehensive Narrative Review [0.03%]
降糖药物对肺部疾病影响的综合叙述性回顾
Yu Yang,Kan Wang,Shuchun Chen
Yu Yang
Beyond glycemic control, hypoglycemic agents exhibit multifaceted effects that may influence pulmonary health in patients with diabetes mellitus. This narrative review synthesizes available evidence from preclinical and clinical studies on ...
Exploring the Potential Value of Lactylation and Macrophage Polarization-Related Genes as Biomarkers for TNF-α Inhibitor Response in Inflammatory Bowel Disease [0.03%]
探索乳酰化及与巨噬细胞极化相关基因作为炎症性肠病TNF-α抑制剂应答生物标志物的潜力
Lichun Han,Guangfu Lin,Xiaodan Lv et al.
Lichun Han et al.
Background: Lactylation has emerged as a novel post-translational modification, and genes linked to both lactylation and macrophage polarization may play a role in inflammatory bowel disease (IBD). However, the connection...
Lysophosphatidylcholine as a Novel Diagnostic Biomarker in Kawasaki Disease: Based on Immunometabolism-Related Signature [0.03%]
基于免疫代谢相关标志物的 lysophosphatidylcholine 作为川崎病新型诊断生物标志物的研究
Xiaomei Ma,Yang Zheng,Chenhui Feng et al.
Xiaomei Ma et al.
Purpose: Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. Delayed diagnosis and treatment elevate the risk of coronary artery complications. This study aims to investigate metabolic disorders associated...
Dupilumab-Induced Systemic Hypoperfusion in an Elderly Patient: A Case Report [0.03%]
依那西普引起的老年人全身组织灌注不足的一例报告
Huishang Feng,Yao Liu,Xinglu Dong et al.
Huishang Feng et al.
Background: Dupilumab is generally considered safe and effective for treating bullous pemphigoid (BP). We report the first case of recurrent hypoperfusion-induced cerebral infarction temporally associated with dupilumab a...
LncRNA PCED1B-AS1 Inhibits Sepsis-Induced Acute Kidney Injury by Promoting Transformation of Macrophages from M1 to M2 Type via Regulating the miR-361-3p/SOCS1 Axis [0.03%]
长链非编码RNA PCED1B-AS1通过调节miR-361-3p/SOCS1轴促进巨噬细胞从M1向M2型转化从而抑制脓毒症诱导的急性肾损伤
Peng Huang,Youfu Li,SiDan Wang et al.
Peng Huang et al.
Purpose: A common complication observed in septic patients under intensive care is acute kidney injury (AKI), which is characterized by acute onset and strong inflammation, resulting in poor clinical outcomes for patients...
Eosinophilic Granulomatosis with Polyangiitis Presenting as Acute Abdomen: A Rare Case Report [0.03%]
以急性腹痛为首发表现的嗜酸性肉芽肿伴多血管炎一例报告
Yan Liao,Jiao Xiong,Wenlong Huang
Yan Liao
Background: ANCA-associated vasculitis (AAV) is a group of autoimmune diseases characterized by necrotizing inflammation and fibrinoid necrosis of small- and medium-sized blood vessels. Renal involvement is common in AAV;...
Siji Kangbingdu Mixture Ameliorates LPS-Induced Acute Lung Injury by Downregulating the TNF/IL-17 Signaling Pathways: A Comprehensive Study Using Transcriptomics, Network Pharmacology and Experimental Verification [0.03%]
四基康邦都散剂通过下调TNF/IL-17信号通路改善脂多糖诱导的急性肺损伤：转录组学、网络药理学和实验验证的综合研究
Yuan Wang,Huiying Zhou,Bo Wang et al.
Yuan Wang et al.
Background: Acute lung injury (ALI), as a respiratory condition triggered by various internal and external factors, is characterized clinically by high rates of incidence and mortality. In the current context where respir...
The eNAMPT-Integrin α5β1 Axis Mediates Neutrophil-Endothelial Cell Interactions Driving Inflammation in Ulcerative Colitis [0.03%]
肠炎性 neutrophil-内皮细胞相互作用中的eNAMPT-整合素α5β1轴介导机制
Yongcheng Di,Wenbin Ji,Wenhao Xiong et al.
Yongcheng Di et al.
Background: Ulcerative colitis (UC), a chronic inflammatory bowel disease with rising global incidence, involves neutrophil-driven mucosal damage. The precise mechanisms remain elusive, hindering targeted therapies. There...