Personalized Treatment for Crohn's Disease: Current Approaches and Future Directions [0.03%]
克罗恩病的个性化治疗：当前方法与未来方向
Joseph William Clinton,Raymond Keith Cross
Joseph William Clinton
Crohn's disease is a complex, relapsing and remitting inflammatory disorder of the gastrointestinal tract with a variable disease course. While the treatment options for Crohn's disease have dramatically increased over the past two decades,...
PSMA-Targeted PET Radiotracer [18F]DCFPyL as an Imaging Biomarker in Inflammatory Bowel Disease [0.03%]
用于炎症性肠病的PSMA靶向PET放射示踪剂[18F]DCFPyL作为影像学生物标志物
Mohamed Saleh Ismail,Diane E Peters,Steven P Rowe et al.
Mohamed Saleh Ismail et al.
Background: Prostate-specific membrane antigen (PSMA) is highly and specifically upregulated in active-inflamed mucosa of patients with inflammatory bowel disease (IBD). We hypothesized that this upregulation would be det...
Gardenia Iridoid Glucosides Protect Against α-Naphthalene Isothiocya-Nate-Induced Cholestatic Rats Through Activation of the FXR-SHP Signaling Pathway [0.03%]
白花丹参素通过激活FXR-SHP信号通路保护α-萘异硫氰酸盐诱导的胆汁淤积大鼠肝脏损伤
Meng Xu,Ke Che,Cong Wang et al.
Meng Xu et al.
Introduction: Cholestasis is a common liver disorder that currently has limited treatment options. Gardenia Iridoid Glucosides (GIG) have been found to possess various physiological activities, such as cholagogic, hypogly...
Body Mass Index Profile of Adult Patients with Inflammatory Bowel Disease in a Multicenter Study in Northeastern Brazil [0.03%]
巴西东北部多中心炎症性肠病成人患者体质指数分析
Jones Silva Lima,Carlos Alexandre Antunes de Brito,Lívia Medeiros Soares Celani et al.
Jones Silva Lima et al.
Purpose: Inflammatory bowel disease (IBD) is a disease of increasing prevalence in developing countries. Obesity has emerged as a potential risk for IBD; however, the data in the literature are conflicting, and relevant s...
Dumping Syndrome: Pragmatic Treatment Options and Experimental Approaches for Improving Clinical Outcomes [0.03%]
倾倒综合征的实用治疗选择及改善临床疗效的实验方法
Gwen M C Masclee,Ad A M Masclee
Gwen M C Masclee
Dumping syndrome is a common complication after esophageal, gastric and bariatric surgery and has a significant negative impact on the quality of life of patients. This narrative review describes the clinical syndrome, pathophysiology, diag...
Indications and Findings of Upper Gastrointestinal Endoscopy at a Tertiary Hospital in Ethiopia: A Cross-Sectional Study [0.03%]
埃塞俄比亚一家三级医院上消化道内镜的适应证和结果：一项横断面研究
Abel Mureja Argaw,Samrawit Solomon Ethiopia,Geda Lelisa et al.
Abel Mureja Argaw et al.
Background: Gastrointestinal disease is a significant global health problem. Symptoms related to digestive system diseases negatively affect quality of life and impose a significant economic impact. Upper gastrointestinal...
Wandering Spleen and Acute Gastric Volvulus in an Elderly Woman with Acute Abdomen: A Case Report [0.03%]
老年急性腹痛患者游走脾和急性胃扭转1例报告
Somprakas Basu,Arvind Pratap,Satyanam Kumar Bhartiya et al.
Somprakas Basu et al.
Gastric volvulus is an uncommon clinical condition with the potentially life-threatening complication of acute gastric necrosis. A wandering spleen may also be associated with gastric volvulus and can produce a diagnostic dilemma as the cau...
Prevalence of Oral Helicobacter pylori Infection in an Indigenous Community in Southwest Mexico [0.03%]
墨西哥西南部一个土著社区口腔幽门螺杆菌感染的流行率
Victor Hugo Urrutia-Baca,Karen Ivonne Gonzalez Brosig,Alina Abigail Salazar-Garza et al.
Victor Hugo Urrutia-Baca et al.
Purpose: Epidemiological studies have been conducted to improve the health and economic quality of life of indigenous communities in Mexico. These studies have found that infections cause frequent health problems. Helicob...
A Multicenter Randomized Phase II Trial Investigating the Effect of Polyglycolic Acid Sheet on the Prevention of Pancreatic Fistula After Gastrectomy with Prophylactic Lymph Node Dissection [0.03%]
一项多中心随机Ⅱ期临床研究：预防性淋巴结清扫术后胃切除患者应用聚谷氨酸垫片预防胰瘘的疗效观察
Dai Shimizu,Chie Tanaka,Mitsuro Kanda et al.
Dai Shimizu et al.
Pancreatic fistula after gastrectomy with lymph node dissection is associated with prolonged hospital stay and critical complications such as intra-abdominal bleeding and sepsis. Polyglycolic acid (PGA) sheets are absorbable suture reinforc...
Emerging Therapies for Ulcerative Colitis: Updates from Recent Clinical Trials [0.03%]
近期临床试验更新的溃疡性结肠炎新兴疗法
Turki AlAmeel,Abdulelah AlMutairdi,Badr Al-Bawardy
Turki AlAmeel
Ulcerative colitis (UC) is a chronic and progressive inflammatory disorder that affects the colon. The advent of advanced therapies such as biologic agents and small molecules has revolutionized the management of UC. Despite the expanding t...