An Overview of the Effects of Tenapanor on Visceral Hypersensitivity in the Treatment of Irritable Bowel Syndrome with Constipation [0.03%]
泰拉匹拉对便秘型肠易激综合征患者内脏高敏感影响的系统评价及meta分析
Prashant Singh,Gregory S Sayuk,David P Rosenbaum et al.
Prashant Singh et al.
Background: Patients with irritable bowel syndrome with constipation (IBS-C) experience persistent abdominal pain, a common symptom leading to greater healthcare utilization and reports of treatment non-response. Clinical...
Optimal Management of Refractory Crohn's Disease: Current Landscape and Future Direction [0.03%]
对难治性克罗恩病的优化管理：现状与未来方向
Kate E Lee,Violet Y Tu,Adam S Faye
Kate E Lee
Refractory Crohn's disease, defined as ongoing inflammation despite the trial of multiple advanced therapies, impacts a number of individuals with Crohn's disease, and leads to significant burden in quality of life and cost. Interventions s...
TCHH as a Novel Prognostic Biomarker for Patients with Gastric Cancer by Bioinformatics Analysis [0.03%]
生物信息学分析发现TCHH是胃癌患者的新型预后生物标志物
Fu Yu,Li Xia Zhao,Shangqi Chu
Fu Yu
Background: This study aims to investigate the clinicopathological significance and prognostic value of Trichohyalin (TCHH) in gastric cancer patients through bioinformatics analysis. ...
Clinicopathological Characteristics, Treatment and Prognosis in Duodenal Adenocarcinoma with Liver Metastasis: A SEER-Based Study [0.03%]
伴有肝转移的十二指肠腺癌临床病理特征、治疗及预后的SEER数据库研究
Zhengchun Zhu,Hong Liu,Fei Zhong
Zhengchun Zhu
Background and objectives: Duodenal adenocarcinoma (DAC) is a rare tumor that is often accompanied by liver metastasis in advanced stages. The aim of this study was to evaluate the correlation between clinicopathological ...
A Novel Rat Model to Simulate the Benign Esophageal Stricture Induced by Endoscopic Submucosal Dissection [0.03%]
模拟内镜粘膜下剥离术后良性食管狭窄的新大鼠模型
Yin-Gen Luo,Xiao-Wu Zhang,He Zhao et al.
Yin-Gen Luo et al.
Objective: This study aimed to establish a rat model that simulates benign esophageal strictures induced by endoscopic submucosal dissection (ESD). Materi...
Endoscopic-Assisted Percutaneous Sigmoidopexy: New Highlights on Technique and Outcomes [0.03%]
内镜辅助经皮乙状结肠固定术：技术与疗效的新亮点
Abdel Rahman A Al Manasra,Tarik Alhmoud,Zaid Mesmar et al.
Abdel Rahman A Al Manasra et al.
Background: Sigmoid volvulus is primarily a disease of the elderly. Case presentation: We describe a case of recurrent sigmoid volvulus...
Relevance of Procalcitonin Levels as a Marker of Severity and Predictor of Mortality, Initiation and Duration of Antibiotics in Patients Admitted with Acute Pancreatitis: A Retrospective Cohort Study [0.03%]
降钙素原水平作为急性胰腺炎患者病情严重程度和死亡率的标志物及预测抗生素使用期限的回顾性队列研究
Baldeep Kaur Mann,Janpreet Singh Bhandohal,Ishaan Kalha et al.
Baldeep Kaur Mann et al.
Introduction: Procalcitonin levels have been studied to predict the benefit of adding antibiotics in a patient with acute pancreatitis. Through this study, we are searching for any possible correlation between serum proca...
Magnetic Resonance Enterography Assessment of Transmural Healing with Vedolizumab in Moderate to Severe Crohn's Disease: Feasibility in the VERSIFY Phase 3 Clinical Trial [0.03%]
维多利珠单抗在中重度克罗恩病中的透壁性愈合的磁共振小肠显像评估：VERSIFY III期临床试验中的可行性研究
Jordi Rimola,Jean-Frédéric Colombel,Brian Bressler et al.
Jordi Rimola et al.
Purpose: The VERSIFY phase 3 trial in patients with Crohn's disease (CD) treated with vedolizumab was the first to include a substudy that used a standardized magnetic resonance enterography (MRE) protocol to assess featu...
Obstacles to Early Diagnosis of Acute Hepatic Porphyria: Current Perspectives on Improving Early Diagnosis and Clinical Management [0.03%]
急性肝卟啉病早期诊断的障碍：改善早期诊断和临床管理的当前观点
Manish Thapar,Akash Singh,Kevin M Robinson et al.
Manish Thapar et al.
Porphyrias are, for the most part, inherited disorders of the heme biosynthetic pathway which lead to accumulation of specific intermediates responsible for most of the symptoms and signs of biochemically active disease. Acute hepatic porph...
Development of a Pharmacokinetic Model That Accounts for the Plasma Concentrations of Conjugated and Unconjugated Bilirubin Observed in a Variety of Disease States [0.03%]
开发一种药代动力学模型来解释各种疾病状态下所观察到的结合和未结合胆红素的血浆浓度变化
David G Levitt,Michael D Levitt
David G Levitt
Introduction: For a large variety of liver pathologies, the plasma unconjugated (UB) and conjugated (CB) bilirubin concentrations appear to be coupled. For example, in alcoholic cirrhosis, UB and CB are roughly the same o...