Developments in treating metastatic colorectal cancer: Recent international reports from ASCO 2007 and 2008 [0.03%]
转移性结直肠癌治疗进展：来自ASCO 2007和2008年国际报告的近况分析
Michel Ducreux
Michel Ducreux
Introduction: Treatment for metastatic colorectal cancer (mCRC), employing various schedules, combinations, and regimens utilizing 5-fluorouracil (5-FU), irinotecan, oxaliplatin, capecitabine, bevacizumab, and cetuximab, ...
Selected luminal mucosal complications of adult celiac disease [0.03%]
成人肠病性自主神经ganglionosis的黏膜并发症選項
Hugh J Freeman
Hugh J Freeman
Celiac disease is a gluten-dependent intestinal disorder that appears to be associated with several clinical conditions. Some involve the luminal mucosa of the stomach and intestinal tract and may, occasionally, complicate the course of cel...
Accuracy of identification of tissue types in endoscopic esophageal mucosal biopsies used for molecular biology studies [0.03%]
内镜下食管黏膜活检标本组织类型的识别精度及其在分子生物学研究中的应用
Plauto Beck,George C Mayne,David Astill et al.
Plauto Beck et al.
Objectives: To determine if histopathologic assessment of esophageal biopsies harvested for research study is justified due to the heterogeneity of tissues in the esophagus, and the consequent histopathologic mis-matches ...
Beverley Greenwood-Van Meerveld,Kelly M Standifer
Beverley Greenwood-Van Meerveld
Constipation is a significant problem related to opioid medications used to manage pain. This review attempts to outline the latest findings related to the therapeutic usefulness of a μ opioid receptor antagonist, methylnaltrexone in the t...
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis [0.03%]
疏水性胆酸、基因组不稳定、达尔文选择及结肠致癌作用
Claire M Payne,Carol Bernstein,Katerina Dvorak et al.
Claire M Payne et al.
Sporadic colon cancer is caused predominantly by dietary factors. We have selected bile acids as a focus of this review since high levels of hydrophobic bile acids accompany a Western-style diet, and play a key role in colon carcinogenesis....
Oropharyngeal Crohn's disease [0.03%]
口咽克罗恩病
Rachid Mohamed,Robert Schultz,Richard N Fedorak
Rachid Mohamed
Crohn's disease is a chronic inflammatory disease that can affect any part of the gastrointestinal tract. Classically the disease has a predilection for the distal small bowel and colon and presents with dominant symptoms of abdominal pain ...
Hatim My Mudawi
Hatim My Mudawi
Hepatitis virus infections are the most common cause of liver disease worldwide. Sudan is classified among the countries with high hepatitis B virus seroprevalence. Exposure to the virus varied from 47%-78%, with a hepatitis B surface antig...
Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome [0.03%]
有机阴离子转运多肽1B3(OATP1B3)在结直肠肿瘤中过度表达并可作为临床预后的预测指标
Albert Craig Lockhart,Elizabeth Harris,Bonnie J Lafleur et al.
Albert Craig Lockhart et al.
Background and aims: OATP1B3 is an organic anion transporting polypeptide (OATP) that functions as a multispecific transporter in the normal liver. We examined the expression and clinical significance of OATP1B3 in colon ...