Cause for controversy? Infliximab in the treatment of ulcerative colitis: an update [0.03%]
英夫利昔单抗治疗溃疡性结肠炎的争议原因？更新版
Garrett Lawlor,Alan C Moss
Garrett Lawlor
Infliximab is a monoclonal antibody against tumor necrosis factor (TNF) which has become an established therapy for Crohn's disease over the last 10 years. Given the similarities between Crohn's disease and ulcerative colitis (UC), it is no...
Update on the role of modified release mesalamine in the management of ulcerative colitis and Crohn's disease [0.03%]
关于改良释药美沙拉嗪在溃疡性结肠炎和克罗恩病治疗中的作用的最新研究进展
Glen A Doherty,Mark A Peppercorn
Glen A Doherty
5-aminosalicyclates (5-ASA) remain a key first-line therapy for patients with ulcerative colitis (UC). A range of 5-ASA preparations is available and Eudragit-S(®) coated modified release formulations of mesalamine, such as Asacol(®), rem...
Ole Gebbensleben,York Hilger,Henning Rohde
Ole Gebbensleben
Background: It is unknown which proctological position is most embarrassing to patients. Methods: Individuals consecutively referred to...
Manoj Kela,Ashish Agrawal,Rajesh Sharma et al.
Manoj Kela et al.
Massive rectal bleeding is an uncommon presentation of ileal tuberculosis. Fewer than 12 cases are reported in the literature. We report a case of ileal tuberculosis presenting at the emergency department with subacute intestinal obstructio...
Delayed release dexlansoprazole in the treatment of GERD and erosive esophagitis [0.03%]
缓释 Dexlansoprazole 治疗胃食管反流病和糜烂性食管炎
Eric T Wittbrodt,Charles Baum,David A Peura
Eric T Wittbrodt
Although proton pump inhibitors (PPI) have a record of remarkable effectiveness and safety in the management of gastroesophageal reflux disease (GERD), several treatment challenges with PPI have emerged. Dexlansoprazole MR is the (R)-enanti...
Anastasios Koulaouzidis,Sarah Douglas
Anastasios Koulaouzidis
Until recently, the small bowel was considered a 'no man's land' as the imaging modalities available for its investigation were laborious, invasive, costly, or involve significant radiation exposure. Wireless capsule endoscopy (WCE) has cha...
The impact of biologics on health-related quality of life in patients with inflammatory bowel disease [0.03%]
生物制剂对炎症性肠病患者健康相关生活质量的影响
Lauran Vogelaar,Adriaan Van&#x;t Spijker,C Janneke van der Woude
Lauran Vogelaar
Background: Inflammatory bowel disease (IBD) is characterized by a chronic relapsing inflammation of the gastrointestinal tract. Adult IBD patients suffer from a disabling disease which greatly affects health-related qual...
Efficacy and tolerability of Laxatan Granulat in patients with chronic constipation [0.03%]
利拉萨坦颗粒治疗慢性便秘患者的疗效和耐受性
Joerg Gruenwald,Regina Busch,Christine Bentley
Joerg Gruenwald
Background: On average 12% of the population worldwide suffer from acute or chronic constipation. Pathological intestine alterations, an unhealthy diet with reduced liquid intake, and little exercise are potential reasons...
Low serum myeloperoxidase in autistic children with gastrointestinal disease [0.03%]
自闭症伴胃肠疾病患儿血清髓过氧化物酶降低
Anthony J Russo,Arthur Krigsman,Bryan Jepson et al.
Anthony J Russo et al.
Aim: To assess serum myeloperoxidase (MPO) levels in autistic children with severe gastrointestinal (GI) disease and to test the hypothesis that there is an association between serum MPO concentration and inflammatory GI ...
Outcome for esophageal cancer following treatment with chemotherapy and radiotherapy but not esophagectomy: Nonsurgical treatment of esophageal cancer [0.03%]
化疗和放疗治疗食管癌的效果：非手术治疗食管癌
Urs Zingg,Dennis Divalentino,Alexander McQuinn et al.
Urs Zingg et al.
Background: More than 50% of patients with esophageal cancer are not suitable for surgery. The aim of this study was to analyze the outcome of patients undergoing standard nonsurgical treatment. ...