Second-Line Treatment of Pancreatic Adenocarcinoma: Shedding Light on New Opportunities and Key Talking Points from Clinical Trials [0.03%]
胰腺导管腺癌二线治疗：临床试验带来新希望及关键看点
Robin Imperial,Osama Mosalem,Umair Majeed et al.
Robin Imperial et al.
Despite improvements in overall cancer mortality, deaths related to pancreatic cancer continue to rise. Following first-line treatment, second-line options are significantly limited. Classically, first-line treatment consisted of either gem...
A Systematic Review: Fecal Bacterial Profile in Patients with Irritable Bowel Syndrome Analyzed with the GA-Map Dysbiosis Test Based on the 16S rRNA Gene of Bacterial Species or Groups [0.03%]
基于细菌物种或菌群的16S rRNA基因的GA-MAP菌群失调检测技术下的肠易激综合征患者粪便细菌谱的系统评价研究
Erica Sande Teige,Urd Sortvik,Gülen Arslan Lied
Erica Sande Teige
Purpose: The diagnosis of irritable bowel syndrome (IBS) is based on symptom-based criteria due to lack of reliable disease-specific biomarkers. Gut microbiota is perturbed in IBS and when comparing different methods used...
Rectovaginal Fistulas Not Involving the Rectovaginal Septum Should Be Treated Like Anal Fistulas: A New Concept and Proposal for a Reclassification of Rectovaginal Fistulas [0.03%]
rectovaginal瘘如未累及直肠阴道隔则应按肛瘘治疗：新概念和rectovaginal瘘再分类建议
Pankaj Garg,Laxmikant Ladukar,Vipul D Yagnik et al.
Pankaj Garg et al.
Background: Many rectovaginal fistulas(RVF), especially low RVF, do not involve/penetrate the RV-septum, but due to lack of proper nomenclature, such fistulas are also managed like RVF (undertaking repair of RV-septum) an...
An Overview of the Effects of Tenapanor on Visceral Hypersensitivity in the Treatment of Irritable Bowel Syndrome with Constipation [0.03%]
泰拉匹拉对便秘型肠易激综合征患者内脏高敏感影响的系统评价及meta分析
Prashant Singh,Gregory S Sayuk,David P Rosenbaum et al.
Prashant Singh et al.
Background: Patients with irritable bowel syndrome with constipation (IBS-C) experience persistent abdominal pain, a common symptom leading to greater healthcare utilization and reports of treatment non-response. Clinical...
Optimal Management of Refractory Crohn's Disease: Current Landscape and Future Direction [0.03%]
对难治性克罗恩病的优化管理：现状与未来方向
Kate E Lee,Violet Y Tu,Adam S Faye
Kate E Lee
Refractory Crohn's disease, defined as ongoing inflammation despite the trial of multiple advanced therapies, impacts a number of individuals with Crohn's disease, and leads to significant burden in quality of life and cost. Interventions s...
TCHH as a Novel Prognostic Biomarker for Patients with Gastric Cancer by Bioinformatics Analysis [0.03%]
生物信息学分析发现TCHH是胃癌患者的新型预后生物标志物
Fu Yu,Li Xia Zhao,Shangqi Chu
Fu Yu
Background: This study aims to investigate the clinicopathological significance and prognostic value of Trichohyalin (TCHH) in gastric cancer patients through bioinformatics analysis. ...
Clinicopathological Characteristics, Treatment and Prognosis in Duodenal Adenocarcinoma with Liver Metastasis: A SEER-Based Study [0.03%]
伴有肝转移的十二指肠腺癌临床病理特征、治疗及预后的SEER数据库研究
Zhengchun Zhu,Hong Liu,Fei Zhong
Zhengchun Zhu
Background and objectives: Duodenal adenocarcinoma (DAC) is a rare tumor that is often accompanied by liver metastasis in advanced stages. The aim of this study was to evaluate the correlation between clinicopathological ...
A Novel Rat Model to Simulate the Benign Esophageal Stricture Induced by Endoscopic Submucosal Dissection [0.03%]
模拟内镜粘膜下剥离术后良性食管狭窄的新大鼠模型
Yin-Gen Luo,Xiao-Wu Zhang,He Zhao et al.
Yin-Gen Luo et al.
Objective: This study aimed to establish a rat model that simulates benign esophageal strictures induced by endoscopic submucosal dissection (ESD). Materi...
Endoscopic-Assisted Percutaneous Sigmoidopexy: New Highlights on Technique and Outcomes [0.03%]
内镜辅助经皮乙状结肠固定术：技术与疗效的新亮点
Abdel Rahman A Al Manasra,Tarik Alhmoud,Zaid Mesmar et al.
Abdel Rahman A Al Manasra et al.
Background: Sigmoid volvulus is primarily a disease of the elderly. Case presentation: We describe a case of recurrent sigmoid volvulus...
Relevance of Procalcitonin Levels as a Marker of Severity and Predictor of Mortality, Initiation and Duration of Antibiotics in Patients Admitted with Acute Pancreatitis: A Retrospective Cohort Study [0.03%]
降钙素原水平作为急性胰腺炎患者病情严重程度和死亡率的标志物及预测抗生素使用期限的回顾性队列研究
Baldeep Kaur Mann,Janpreet Singh Bhandohal,Ishaan Kalha et al.
Baldeep Kaur Mann et al.
Introduction: Procalcitonin levels have been studied to predict the benefit of adding antibiotics in a patient with acute pancreatitis. Through this study, we are searching for any possible correlation between serum proca...