M Aamir Ali,Marie L Borum
M Aamir Ali
Up to 93% of patients with hereditary angioedema (HAE) experience recurrent abdominal pain. Many of these patients, who often present to emergency departments, primary care physicians, general surgeons, or gastroenterologists, are misdiagno...
Reexamination of the relationship between the prevalence of hepatitis C virus and parenteral antischistosomal therapy among Egyptians resident in Qatar [0.03%]
关于卡塔尔埃及居民丙型肝炎病毒流行率与体液抗血吸虫病治疗关系的再研究
Moutaz Derbala,Prem Chandra,Aliaa Amer et al.
Moutaz Derbala et al.
Egypt has the highest prevalence of recorded hepatitis C virus (HCV) worldwide, estimated nationally at 14.7%, which is attributed to extensive iatrogenic transmission during the era of parenteral antischistosomal therapy (PAT) mass-treatme...
Fungal infection of the colon [0.03%]
结肠真菌感染
Surat Praneenararat
Surat Praneenararat
Fungi are pathogens that commonly infect immunocompromised patients and can affect any organs of the body, including the colon. However, the literature provides limited details on colonic infections caused by fungi. This article is an inten...
Matjaz Rokavec,Huihui Li,Longchang Jiang et al.
Matjaz Rokavec et al.
The protein encoded by the TP53 gene is one of the most important suppressors of tumor formation, which is also frequently inactivated in gastrointestinal cancer. MicroRNAs (miRNAs) are small noncoding RNAs that inhibit translation and/or p...
Psychometric validation of patient-reported outcome measures assessing chronic constipation [0.03%]
慢性便秘患者报告结果测量的量表学验证研究
Lauren M Nelson,Valerie Sl Williams,Sheri E Fehnel et al.
Lauren M Nelson et al.
Background: Measures assessing treatment outcomes in previous CC clinical trials have not met the requirements described in the US Food and Drug Administration's guidance on patient-reported outcomes. ...
Long-term efficacy and safety of once-daily mesalazine granules for the treatment of active ulcerative colitis [0.03%]
一次每日美沙拉秦颗粒剂治疗活动期溃疡性结肠炎的长期疗效和安全性研究
Stephan Karl Böhm,Wolfgang Kruis
Stephan Karl Böhm
In 1977, 5-aminosalicylic acid (5-ASA) was discovered as a therapeutically active moiety of sulfasalazine (SASP) and was launched for topical and oral therapy of ulcerative colitis (UC) in 1984. As a first-step, delivery systems had to be d...
Clinical potential of naloxegol in the management of opioid-induced bowel dysfunction [0.03%]
纳洛西硐对阿片类药物引起的肠功能紊乱的临床应用前景
Jakob Lykke Poulsen,Christina Brock,Anne Estrup Olesen et al.
Jakob Lykke Poulsen et al.
Opioid-induced bowel dysfunction (OIBD) is a burdensome condition which limits the therapeutic benefit of analgesia. It affects the entire gastrointestinal tract, predominantly by activating opioid receptors in the enteric nervous system, r...
Management of inflammatory bowel disease in poor responders to infliximab [0.03%]
英夫利昔治疗反应不佳的炎症性肠病患者的管理
Iván Guerra,Fernando Bermejo
Iván Guerra
Infliximab (IFX) is an effective treatment for inducing and maintaining response in Crohn's disease and ulcerative colitis patients. Some patients present lack of response or loss of response to IFX during maintenance therapy. Empirical man...
Rainer Ganschow,Jörg-Matthias Pollok,Martin Jankofsky et al.
Rainer Ganschow et al.
During the last 5 decades, liver transplantation has witnessed rapid development in terms of both technical and pharmacologic advances. Since their discovery, calcineurin inhibitors (CNIs) have remained the standard of care for immunosuppre...
Quantitative assessment of the multiple processes responsible for bilirubin homeostasis in health and disease [0.03%]
健康和疾病状态下定量评估胆红素稳态的多种过程
David G Levitt,Michael D Levitt
David G Levitt
Serum bilirubin measurements are commonly obtained for the evaluation of ill patients and to screen for liver disease in routine physical exams. An enormous research effort has identified the multiple mechanisms involved in the production a...