The Effectiveness of Right- vs Left-lateral Starting Position in Unsedated Diagnostic Colonoscopy with Modified-water Immersion Method: A Randomized Controlled Trial Study [0.03%]
镇静检查结肠镜中右侧位与左侧位起始位置的效果对比改良水浸法的随机对照试验研究
Putut Bayupurnama,Neneng Ratnasari,Fahmi Indrarti et al.
Putut Bayupurnama et al.
Objective: A colonoscopy study in sedated patients with air insufflation showed that right-lateral starting position (RLP) improved abdominal discomfort and reduced cecal intubation time. The aim of this study was to dete...
Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats [0.03%]
肠道菌群失调和增加的肠通透性促进微核糖核酸、NLRP-3炎症小体和大鼠非酒精脂肪性肝炎纤维化
Larisse Longo,Jéssica Tonin Ferrari,Pabulo Henrique Rampelotto et al.
Larisse Longo et al.
Background/aim: The interactions between the gut and liver have been described in the progression of non-alcoholic steatohepatitis (NASH). The aim of this study was to develop an experimental nutritional model of NASH sim...
Risk of Lymphoma Associated with Anti-TNF Therapy in Patients with Inflammatory Bowel Disease: Implications for Therapy [0.03%]
抗肿瘤坏死因子治疗与炎症性肠病患者淋巴瘤风险的相关性：对治疗的启示
Jessica Dahmus,Michelle Rosario,Kofi Clarke
Jessica Dahmus
Anti-tumor necrosis factor alpha (ATA) therapy plays a significant role in the treatment of moderate to severe inflammatory bowel disease (IBD). There are concerns regarding risks associated with their use, including malignancy and, specifi...
Quantitative Evaluation of D-Lactate Pathophysiology: New Insights into the Mechanisms Involved and the Many Areas in Need of Further Investigation [0.03%]
D-乳酸病理生理的定量评估：新的机制见解及未来研究领域
Michael D Levitt,David G Levitt
Michael D Levitt
In contrast to L-lactate, D-lactate is produced in minimal quantities by human cells, and the plasma D-lactate concentration normally is maintained at a concentration of only about 0.01 mM. However, in short bowel syndrome, colonic bacteria...
Hidradenitis Suppurativa as a Paradoxical Side Effect to the Use of Adalimumab in Patients with Crohn's Disease? [0.03%]
腺炎作为克罗恩病患者使用阿达木单抗的悖论副作用？
Rodrigo Fedatto Beraldo,Mariana Barros Marcondes,Julio Pinheiro Baima et al.
Rodrigo Fedatto Beraldo et al.
Background: Hidradenitis suppurativa is a chronic inflammatory skin disorder associated with inflammatory bowel disease. However, it can arise as a paradoxical side effect of anti-TNF treatment. ...
Changes in Function and Dynamics in Hepatic and Splenic Macrophages in Non-Alcoholic Fatty Liver Disease [0.03%]
非酒精性脂肪肝病中肝脏和脾脏巨噬细胞的功能及动态变化
Hisataka Fukushima,Hiroshi Kono,Kazuyoshi Hirayama et al.
Hisataka Fukushima et al.
Background: The aim of this study was to investigate the populations and functions of hepatic and splenic macrophages (Mfs) in non-alcoholic fatty liver disease (NAFLD). ...
Increases in Autoantibody Level Associated with Degenerative Changes in the Intestinal Mucosa in Liver Cirrhosis [0.03%]
肝硬化肠道黏膜退行性病变与自身抗体水平升高有关
Radmila V Karpova,Ksenia S Russkova,Yuliya N Lavrentieva
Radmila V Karpova
Background: Portal hypertensive colonopathy is a consequence of portal hypertension that develops in hepatic cirrhosis. Pathological processes occurring in intestinal epithelium cells can be revealed by changes in the aut...
Prevalence and Risk Factors of Hyperuricemia in Patients with Chronic Kidney Disease and Non-Alcoholic Fatty Liver [0.03%]
慢性肾病和非酒精性脂肪肝患者高尿酸血症的患病率及其危险因素
Sima Golmohammadi,Marjan Tavasoli,Nadia Asadi
Sima Golmohammadi
Background/aims: The number of patients with nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) is on the rise. Epidemiological studies have shown the role of hyperuricemia in the development of NAF...
New Zealand National Audit of Outpatient Inflammatory Bowel Disease Standards of Care [0.03%]
新西兰全国门诊炎症性肠病护理标准审核
Robert Hackett,Richard Gearry,Christine Ho et al.
Robert Hackett et al.
Aim: This study audits the delivery and standards of New Zealand (NZ) inflammatory bowel disease (IBD) care against international standards, with emphasis on the IBD nursing role. ...
Early Detection and Recurrence of Colorectal Adenomas by Combination of Eight Cancer-Associated Biomarkers in Plasma [0.03%]
血浆中八个癌症相关生物标志物联合应用对结肠腺瘤的早期检测和复发判断
Louise Rasmussen,Hans Jørgen Nielsen,Ib Jarle Christensen
Louise Rasmussen
Introduction: Plasma levels of eight combined proteins have shown value as biomarkers for detection of colorectal cancer (CRC). However, their value in identifying colorectal adenoma needs further evaluation. The aim was ...