Network Pharmacology, Molecular Docking and Dynamics Simulation Reveal the Anti-Colitis Mechanism of Smilax glabra Roxb [0.03%]
Yuan Cui,Jingyi Hu,Yanan Li et al.
Yuan Cui et al.
Purpose: A combination of bioinformatics methods including network pharmacology, molecular docking and molecular dynamics simulation was utilized to investigate the potential mechanism of Smilax glabra Roxb. (SG) in the t...
Predictors of In-Hospital Mortality in Helicobacter pylori-Negative, Non-Variceal Upper Gastrointestinal Bleeding: A Retrospective Cohort Study [0.03%]
Giselle María Padilla Gutiérrez,Gregorio Jurado Delgado,Alex Domínguez-Vargas et al.
Giselle María Padilla Gutiérrez et al.
Purpose: With the global decline in Helicobacter pylori infection, upper gastrointestinal bleeding (UGIB) is increasingly driven by non-infectious, non-Nonsteroidal Anti-Inflammatory Drug (NSAID) mechanisms, particularly ...
Rectal Prolapse as a Rare Presentation of Colorectal Cancer: Case Series and Clinical Perspectives [0.03%]
直肠脱垂作为结直肠癌的罕见表现：病例系列和临床视角
Prapanca Nugraha,Kiki Lukman,Tommy Ruchimat et al.
Prapanca Nugraha et al.
Background: Rectal prolapse is the protrusion of the rectum through the anal canal, commonly observed in older women with weakened pelvic floor muscles and anal sphincters. Clinical symptoms may include a painful, irreduc...
The Role of Nuclear APOBEC Enzymes in Neoplastic Progression of Ulcerative Colitis [0.03%]
APOBEC家族核酶在溃疡性结肠炎肿瘤进展中的作用
Lene Alsøe,Stephan Andreas Brackmann,Yan Liu et al.
Lene Alsøe et al.
Aberrant expression of the cytidine DNA deaminase AID in enterocytes within inflamed mucosa in ulcerative colitis (UC) patients has been proposed to be involved in progression of UC to colitis-associated colorectal cancer (CA-CRC). Here, we...
Costs, Demographics, and Causative Agents in Patients Hospitalized for Drug Induced Liver Injury: Trends in a Large Academic Healthcare System [0.03%]
大型学术医疗系统中住院药物性肝损伤患者的成本、人口统计学和致病原因：趋势分析
Megan Kozar,Yunisse Gonzalez,Dina Halegoua-DeMarzio
Megan Kozar
Purpose: Drug-induced liver injury (DILI) is an uncommon but potentially life-threatening condition. To date, the burden of DILI on a single, large healthcare system has not been investigated, preventing adequate resource...
Omalizumab-Induced Remission and Steroid Withdrawal in Refractory Eosinophilic Gastroenteritis with Severe Hypereosinophilia: A Case Report [0.03%]
奥马珠单抗致难治性嗜酸细胞性胃肠炎合并重度嗜酸粒细胞增多症缓解及停用激素1例报告
Zhirong Du,Weixun Zhou,Ji Li et al.
Zhirong Du et al.
Eosinophilic gastroenteritis (EGE) is a rare, immune-mediated disorder characterized by pathological eosinophilic infiltration of the gastrointestinal tract. Corticosteroids are the primary treatment for EGE, but managing patients who are c...
Artificial Intelligence in Gastrointestinal Endoscopy: Current Advances, Clinical Integration, and Future Directions: A Narrative Review [0.03%]
内镜人工智能：目前进展、临床整合和未来方向：综述文章
Vipul D Yagnik,Prema Ram Choudhary,Pankaj Garg
Vipul D Yagnik
Background: Artificial intelligence (AI) has emerged as a transformative force in gastrointestinal (GI) endoscopy, aiming to enhance diagnostic accuracy, detection rates, and workflow efficiency. With multiple AI-assisted...
Toward Integrated Care for Neurogastroenterology and Motility Disorders: A Model for Clinical Practice [0.03%]
神经胃肠病学和运动障碍综合护理的临床实践模型
Fleur H C Veldman,Kim W E Sweerts,Carsten Leue et al.
Fleur H C Veldman et al.
Integrated care refers to the coordinated delivery of health services across providers and settings, aimed at ensuring continuous, patient-centered care throughout the course of disease. Models of integrated care have demonstrated particula...
Gastric Proton Pumpopathy Associated with Protein Sorting Machinery: A Narrative Review [0.03%]
与蛋白质分拣有关的胃质子泵病态生理功能：综述性文章
Aime Patrick Niyomugabo,Leopold Ntakirutimana,Jean Claude Habineza et al.
Aime Patrick Niyomugabo et al.
Background: Gastric acid secretion by parietal cells depends on the trafficking and exocytosis of H⁺/K⁺-ATPase-rich tubulovesicles (TVs) to the apical membrane in response to histamine stimulation via cyclic AMP elevati...
Preliminary Results of Extraperitoneal Rectus Abdominis Anterior Sigmoid Colostomy (ERASC) for Prevention of Parastomal Hernia Following Abdominoperineal Resection [0.03%]
腹会阴切除术后前侧切口结肠造口（ERASC）预防切口疝的初步结果研究
Haolan Yuan,Xiangshu Li,Zhengqiang Wei
Haolan Yuan
Introduction: Among patients with rectal cancer undergoing abdominoperineal resection (APR), parastomal hernia (PSH) is the most common long-term complication. Although extraperitoneal colostomy (EPC) has been proposed as...