Immediate Facial Reanimation After Radical Parotidectomy for Malignancy: Oncologic Principles and Reconstructive Strategy [0.03%]
肿瘤切除的即刻面部重建： oncologic原则和重建策略
Bo Yin,Jia Liu
Bo Yin
This narrative review examines immediate facial reanimation after radical parotidectomy for malignancy within an integrated oncologic and reconstructive framework; no formal systematic evidence synthesis or meta-analysis was performed. Radi...
Literature Review: Recent Therapeutic Advances in The Management of Prurigo Nodularis: From Conventional Therapy to Biologics and Targeted Small-Molecule Agents [0.03%]
特应性痒疹的治疗近况：从传统疗法到生物制剂及小分子靶向药物——文献综述
Erda Avriyanti,Ranisa Larasati,Sithra Rengasamy et al.
Erda Avriyanti et al.
Prurigo nodularis (PN) is a chronic inflammatory disease characterized by hyperkeratotic nodules on extensor surfaces, perpetuating a vicious itch-scratch cycle. Its epidemiologic burden is substantial, and diagnosis remains primarily clini...
Post-Translational Modification-Driven Metabolic Reprogramming Shapes Melanoma Progression and Immune Microenvironment [0.03%]
翻译后文本：翻译后修饰驱动的代谢重塑塑造黑素瘤进展和免疫微环境
Man-Ning Wu,Dong-Mei Zhou,Yue-Min Zou et al.
Man-Ning Wu et al.
Background: Post-translational modifications (PTMs) critically regulate protein function, yet their intratumoral heterogeneity and clinical relevance in melanoma remain poorly characterized. Elucidating PTM-driven program...
Secukinumab in Refractory Generalized Darier's Disease with a 40-Year Disease Duration: A Case Report [0.03%]
长效达里埃病（Dariern病）的塞库今单抗治疗：个例报告
Yangfei Ou,Hui Fang,Tingting Liu et al.
Yangfei Ou et al.
Objective: To report a rare case of refractory generalized Darier's disease (DD), also known as keratosis follicularis, with a disease duration exceeding 40 years and to explore the therapeutic effect of the interleukin-1...
A Narrative Review of the Multi-Target Mechanisms of Glabridin in Skin Lightening [0.03%]
银杏素皮肤美白的多靶点机制综述
Xin Nie,Ziyuan Ma,Anning Wang et al.
Xin Nie et al.
Background: Hyperpigmentation disorders are a leading cause of dermatological consultation worldwide. Conventional depigmenting agents such as hydroquinone and kojic acid primarily target tyrosinase, but their efficacy is...
Clinical Characteristics and Factors Associated with Hair Loss Severity in Chronic Hepatitis B Patients Receiving Pegylated Interferon-Alpha: A Retrospective Cohort Study [0.03%]
接受聚乙二醇干扰素-α治疗的慢性乙肝患者脱发临床特征及影响因素：回顾性队列研究
Xiaodan Wang,Zhenzhen Yan,Cuie Liu et al.
Xiaodan Wang et al.
Objective: To characterize the phenotype and evaluate factors associated with hair loss severity in patients already experiencing alopecia during pegylated interferon alpha therapy or nucleos(t)ide analog therapy for CHB....
Atypical Fibroxanthoma on the Scalp of a 74-Year-Old Male with an Incidental Finding of an Amelanotic Melanoma on the Back [0.03%]
一名74岁男性患者头皮非典型纤维组织增生伴背部无色素性黑色素瘤的偶然发现
Iwona Chlebicka,Martyna Byrska,Klaudia Knecht-Gurwin et al.
Iwona Chlebicka et al.
Atypical fibroxanthoma (AFX) is a rare spindle-cell tumor of the skin, typically occurring in sun-exposed areas of elderly patients. We report an unusual case of synchronous AFX and amelanotic melanoma in a 74-year-old man. The patient pres...
Polynucleotides High Purification Technology: A Real-World Prospective Study in a Hospital Outpatient Setting Supports PN HPT as a Regenerative Medicine Option for Acne Scar Management [0.03%]
聚核苷酸高纯化技术：一项真实世界前瞻性研究支持将PNHPT作为痤疮疤痕管理的再生医学选择
Emanuele Bartoletti,Gloria Trocchi,Ilenia Fiorini et al.
Emanuele Bartoletti et al.
Introduction: A double-blind, placebo-controlled trial demonstrated that Polynucleotides High Purification Technology (PN HPT) are an effective regenerative medicine treatment for moderate-to-severe atrophic post-acne sca...
The Role of Dermocosmetics in Acne Management: Implications for Clinical Practice in Brazil [0.03%]
皮肤病化妆品在巴西痤疮管理中的作用及临床实践意义
Marco Alexandre Da Rocha,Ediléia Bagatin,Brigitte Dréno et al.
Marco Alexandre Da Rocha et al.
Acne is a prevalent skin condition worldwide, affecting diverse populations, including Brazil. Although acne guidelines are well established for topical and/or systemic medications, recommendations regarding dermocosmetics, which have becom...
Screening of Metabolic Reprogramming-Related Diagnostic Biomarkers and Analysis of Immune Heterogeneity in Atopic Dermatitis Based on Multi-Cohort Validation [0.03%]
基于多队列验证的特应性皮炎代谢重构相关诊断标志物筛选及免疫异质性分析
Bingwei Zhi,Xin Song
Bingwei Zhi
Background: Atopic dermatitis (AD), often called eczema, is a long-lasting skin condition that causes severe itching and distress for many people. While we know it involves the immune system and the skin barrier, we still...