Two-Year Integrated Efficacy And Safety Analysis Of Benralizumab In Severe Asthma [0.03%]
贝那利珠单抗治疗重度哮喘2年疗效和安全性综合分析
J Mark FitzGerald,Eugene R Bleecker,Arnaud Bourdin et al.
J Mark FitzGerald et al.
Background: Benralizumab is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody. Treatment with benralizumab significantly reduces exacerbations and improves lung function after 1 year for patients with...
Anxiety and Depression in Eosinophilic Esophagitis: A Scoping Review and Recommendations for Future Research [0.03%]
嗜酸细胞性食管炎中的焦虑和抑郁：系统回顾及对未来研究的建议
Tiffany H Taft,Livia Guadagnoli,Emily Edlynn
Tiffany H Taft
Eosinophilic esophagitis (EoE) is a rapidly emerging chronic disease with limited treatments. Impacting both children and adults, EoE and its treatments have the potential to significantly reduce psychological functioning, including increas...
Neil C Thomson
Neil C Thomson
Purpose: Bronchial thermoplasty is approved in many countries worldwide as a non-pharmacological treatment for severe asthma. This review summarizes recent publications on the selection of patients with severe asthma for ...
Single-Use Autoinjector Functionality And Reliability For At-Home Administration Of Benralizumab For Patients With Severe Asthma: GRECO Trial Results [0.03%]
用于居家给药的单剂量苯拉卢肽自动注射剂在重度哮喘患者中的功能性和可靠性：GRECO试验结果
Gary T Ferguson,Jeremy Cole,Magnus Aurivillius et al.
Gary T Ferguson et al.
Purpose: Accessorized prefilled syringes (APFS) have demonstrated functionality and reliability for subcutaneous (SC) delivery, including self-administration, of benralizumab 30 mg in the clinic or at home. The multicente...
Eleanor C Majellano,Vanessa L Clark,Natasha A Winter et al.
Eleanor C Majellano et al.
Asthma is a chronic condition with great variability. It is characterized by intermittent episodes of wheeze, cough, chest tightness, dyspnea and backed by variable airflow limitation, airway inflammation and airway hyper-responsiveness. As...
IgE-Mediated Systemic Anaphylaxis And Its Association With Gene Polymorphisms Of ACE, Angiotensinogen And Chymase [0.03%]
IgE介导的全身性过敏反应及其与ACE、血管紧张素原和糜蛋白酶基因多态性的关联研究
V A Varney,A Nicholas,A Warner et al.
V A Varney et al.
Background: The renin-angiotensin system (RAS) protects the circulation against sudden falls in systemic blood pressure via generation of angiotensin II (AII). Previously, we demonstrated that patients with anaphylaxis in...
Clinical Utility Of The Exhaled Nitric Oxide (NO) Measurement With Portable Devices In The Management Of Allergic Airway Inflammation And Asthma [0.03%]
便携式一氧化氮检测设备在过敏性气道炎症和哮喘管理中的临床应用价值研究进展
Sy Duong-Quy
Sy Duong-Quy
Nitric oxide (NO) is a potential bioactive gas produced continuously and constantly in the airways of healthy subjects. In allergic airway inflammation, the level of exhaled NO is usually increased and mediated by inducible nitric oxide syn...
Lung Sound Analysis Provides A Useful Index For Both Airway Narrowing And Airway Inflammation In Patients With Bronchial Asthma [0.03%]
肺音分析可作为支气管哮喘患者气道阻塞和气道炎症的有用指标
Terufumi Shimoda,Yasushi Obase,Yukio Nagasaka et al.
Terufumi Shimoda et al.
Background: The expiration-to-inspiration sound power ratio in a midfrequency range (E/I MF), a parameter of lung sound analysis (LSA), has been reported to be useful as an index of airway inflammation in patients with br...
Carlyne M Averell,François Laliberté,Mei Sheng Duh et al.
Carlyne M Averell et al.
Background: Tiotropium bromide (TIO) is a long-acting muscarinic antagonist recommended as an add-on therapy option for patients with uncontrolled asthma on inhaled corticosteroids (ICS) and long-acting β2-agonists (LABA...
Prevalence and impact of risk factors for poor asthma outcomes in a large, specialist-managed patient cohort: a real-life study [0.03%]
大型专科管理患者队列中哮喘不良预后危险因素的流行率和影响：一项真实世界研究
Gábor Tomisa,Alpár Horváth,Zsuzsanna Szalai et al.
Gábor Tomisa et al.
Background: Risk factors for poor asthma outcomes may have considerable influence on the control level and medical care of asthmatic patients. Our objective was to conduct a study that provides data on the level of sympto...