Circulating TFH2 Cell Expansion and GZMK+ TFH1 Cells are Associated with Allergic Rhinitis [0.03%]
循环TFH2细胞增殖和GZMK+ TFH1细胞与过敏性鼻炎相关
Jiejun He,Yueqi Sun,Yang Chen et al.
Jiejun He et al.
Background: Allergic rhinitis (AR) is a prevalent condition characterized by an immunoglobulin E (IgE)-mediated immune response. T follicular helper (TFH) cells regulate B-cell differentiation and antibody production, and...
A Functional Variant of CYP4V2 Contributes to Asthma Susceptibility Through Methylation-Mediated Regulation of the Arachidonic Acid Pathway [0.03%]
CYP4V2的功能性变异通过甲基化介导的花生四烯酸代谢调节影响哮喘易感性
Xiangran Chen,Terence Yin Weng Lam,Yang Yie Sio et al.
Xiangran Chen et al.
Background: CYP4V2 is involved in lipid metabolism, but its contribution to asthma is poorly understood. This study aimed to investigate genetic polymorphisms and regulatory features of CYP4V2 in asthma development. ...
Impact of Overweight and Obesity in Severe Asthma Patients and Its Influence on Achieving Clinical Remission [0.03%]
肥胖对重度哮喘患者的影响及其对实现临床缓解的影响
Mona Al-Ahmad,Asmaa Ali,Wafaa Talat
Mona Al-Ahmad
Background and objectives: Obesity exacerbates asthma, resulting in more severe symptoms, poor disease control, and a reduced quality of life. With the increasing use of biologic therapies, achieving clinical remission (C...
Glucagon-Like Peptide-1 Receptor Agonists vs Dipeptidyl Peptidase-4 Inhibitor Use on Risk of Asthma Exacerbation Among Diabetic Patients with Co-Morbid Asthma in Hong Kong [0.03%]
香港糖尿病合并哮喘患者的GLP-1受体激动剂与DPP-4抑制剂使用对哮喘加重风险的影响
Wang Chun Kwok,Lu Zhou,Ting Fung Ma et al.
Wang Chun Kwok et al.
Background: Co-existing asthma and diabetes mellitus (DM) are common, and there has been a debate on whether glucagon-like peptide-1 (GLP-1)-based therapies, such as GLP-1 receptor agonists (GLP-1RA) and inhibitors of dip...
Exploration of the Potential Mechanisms of Yinqiao Powder in Treating Atopic Dermatitis: Integrating Network Pharmacology, Single-Cell, and Bulk RNA Sequencing [0.03%]
网络药理学、单细胞和批量转录组测序联用探究银翘散治疗特应性皮炎的潜在机制研究
Lila Luo
Lila Luo
Purpose: Yinqiao powder (YQP) is a traditional Chinese medicine formula that has been widely used clinically to treat infectious diseases such as respiratory tract infections, influenza, and pneumonia, exhibiting anti-inf...
Clinical Trial
Journal of asthma and allergy. 2026 Jul 21:19:592593. DOI:10.2147/JAA.S592593 2026
Asthma with Preserved Ratio Impaired Spirometry: A Distinct Phenotype Associated with Increased Exacerbation Burden [0.03%]
比值 preserved 但气流受限的哮喘：一种与急性加重负担增加相关的独特表型
Yoshihito Arimoto,Natsue Honda,Kosuke Haruki et al.
Yoshihito Arimoto et al.
Purpose: Asthma is a heterogeneous disease, and identifying phenotypes associated with an increased exacerbation burden is clinically important. Preserved ratio impaired spirometry (PRISm) has been linked to adverse healt...
Prevalence and Patterns of Allergen Sensitization in Southern China: A Retrospective Analysis of 18,777 Routine Checkup Participants in Shenzhen [0.03%]
中国南方过敏原敏感流行病学及致敏模式——以深圳市18,777例健康体检者回顾性分析为例
Linlin Xu,Changmeng Wu,Juan He et al.
Linlin Xu et al.
Purpose: The distribution of allergens exhibits significant geographic variation. Local epidemiological studies are essential for understanding allergic sensitization patterns, which may inform regional epidemiological re...
Persistent Airflow Limitation in Asthma: Clinical Characteristics, Risk Factors, and Long-term Outcomes from a Multicenter Cohort Study [0.03%]
哮喘患者持续气流受限的临床特征、危险因素和长期预后-多中心队列研究
Jung-Kyu Lee,Hyun-Woo Lee,Chang Hoon Lee et al.
Jung-Kyu Lee et al.
Background: Persistent airflow limitation (PAL) is an increasingly recognized asthma phenotype, but its prevalence, determinants, and prognostic significance in real-world settings remain unclear. This study evaluated the...
Effect of Chewing Gum on Fractional Exhaled Nitric Oxide Values in Patients with Asthma: A Proof of Concept Study [0.03%]
关于评估嚼口香糖对哮喘患者呼出气一氧化氮影响的概念验证性研究
Maria Aetou,Ingmar Bergs,Sitraka Faniry Nantenaina Ratsimba et al.
Maria Aetou et al.
Purpose: Fractional exhaled nitric oxide (FeNO) is an important biomarker that is used to phenotype patients with (severe) asthma. This study evaluated the effect of chewing gum on FeNO values. ...
Clinical Trial
Journal of asthma and allergy. 2026 Jul 3:19:606416. DOI:10.2147/JAA.S606416 2026