Profile of Baricitinib and Its Potential in the Treatment of Moderate to Severe Atopic Dermatitis: A Short Review on the Emerging Clinical Evidence [0.03%]
巴利昔替尼治疗中重度特应性皮炎潜力初探——兼论临床证据的积累效应
Maddalena Napolitano,Gabriella Fabbrocini,Eleonora Cinelli et al.
Maddalena Napolitano et al.
Atopic dermatitis (AD) is the most common chronic cutaneous inflammatory disease of childhood, affecting up to 25% of children; its prevalence in adulthood is currently unknown, since studies reported that AD may affect 0.3-14.3% of adult p...
Real-World Effectiveness of Mepolizumab in Patients with Severe Asthma: An Examination of Exacerbations and Costs [0.03%]
重症哮喘患者美普兹单抗疗效的真实世界研究：复发率及成本分析
Jean-Pierre Llanos,Hector Ortega,Michael Bogart et al.
Jean-Pierre Llanos et al.
Rationale: Results from clinical trials in patients with severe eosinophilic asthma have demonstrated that mepolizumab is well tolerated and is associated with improved asthma control as evidenced by reductions in both ex...
Prevalence and Predictors of Uncontrolled Asthma in Children Referred for Asthma and Other Atopic Diseases [0.03%]
儿童哮喘及其他特应性疾病的诊断和预测因素
H M Kansen,T M Le,Cspm Uiterwaal et al.
H M Kansen et al.
Background: Uncontrolled asthma in children is still highly prevalent despite the availability of effective asthma treatment. We investigated 1) the prevalence of uncontrolled asthma among children referred for asthma and...
Current Controversies and Future Prospects for Peanut Allergy Prevention, Diagnosis and Therapies [0.03%]
peanut过敏预防、诊断和治疗的现状与前景
Claudia Liesel Gray
Claudia Liesel Gray
Peanut allergy has increased substantially in the past few decades, both in developed and developing countries. Peanut allergy has become a major public health concern, affecting up to 1 in 50 children, with repercussions for school and air...
Alan Kaplan,David Price
Alan Kaplan
The burden of asthma is particularly notable in adolescents, and is associated with higher rates of prevalence and mortality compared with younger children. One factor contributing to inadequate asthma control in adolescents is poor treatme...
Confounding Patient Factors Affecting the Proper Interpretation of the Periostin Level as a Biomarker in Asthma Development [0.03%]
哮喘发病过程中 periostin 水平作为生物标志物的正确解读受患者因素的影响
Mahmood Yaseen Hachim,Noha Mousaad Elemam,Rakhee K Ramakrishnan et al.
Mahmood Yaseen Hachim et al.
Introduction: The proper use of serum periostin (POSTN) as a biomarker for asthma is hindered by inconsistent performance in different clinical settings. ...
Exhaled Nitric Oxide in Wheezy Infants Predicts Persistent Atopic Asthma and Exacerbations at School Age [0.03%]
婴儿喘息时呼出的一氧化氮可预测学龄期持续性过敏性哮喘和病情加重
Maria P White,Tessa K Kolstad,Molly Elliott et al.
Maria P White et al.
Background: There are limited data assessing the predictive value of fraction of exhaled nitric oxide (FENO) in infants/toddlers with recurrent wheezing for asthma at school age. ...
Vianney Gruzelle,Claire Mailhol,David W Waters et al.
Vianney Gruzelle et al.
Hymenoptera venom allergy (HVA) is the leading cause of anaphylactic reactions in adults and the second most common cause in children. Venom immunotherapy (VIT) is used to elicit an immune tolerance against hymenoptera venom in allergic pat...
Allergological Study of 565 Elderly Patients Previously Labeled as Allergic to Penicillins [0.03%]
565例原先被标注青霉素过敏的老年人的过敏学研究
Teodorikez Wilfox Jimenez-Rodriguez,Natalia Blanca-Lopez,Maria Ruano-Zaragoza et al.
Teodorikez Wilfox Jimenez-Rodriguez et al.
Purpose: Elderly people thought to have an allergy to beta-lactams (BLs) may tolerate the drugs in subsequent exposures due to initial false labeling of allergies, the spontaneous loss of sensitivity to BLs over time or a...
Parasitic (Helminthic) Infection While on Asthma Biologic Treatment: Not Everything Is What It Seems [0.03%]
生物制剂治疗期间的寄生虫(蠕虫)感染：并非一切都是表象那样
Laren D Tan,Brett Schaeffer,Abdullah Alismail
Laren D Tan
Asthma is a chronic inflammatory disorder of the airway that is characterized by bronchial hyperresponsiveness and variable airflow limitation. Approximately 235 million people are affected by asthma worldwide and 5-10% are considered to be...