In-Hospital Outcomes and Mortality of Pediatric Asthma Exacerbations in Thailand: A Nationwide Study (2015-2022) [0.03%]
泰国儿童哮喘加重的住院结局和死亡率:一项全国性研究(2015-2022年)
Rattapon Uppala,Phanthila Sitthikarnkha,Sirapoom Niamsanit et al.
Rattapon Uppala et al.
Purpose: Asthma is a chronic respiratory disorder that is prevalent and significantly contributes to morbidity and mortality among children globally. However, national data regarding in-hospital outcomes and factors assoc...
Identification of Misdiagnosis Factors in Allergic Bronchopulmonary Mycosis Using Explainable Machine Learning [0.03%]
使用可解释机器学习识别过敏性支气管肺真菌病误诊因素
Xuemei Chen,Zekai Yu,Xiaoxiao Gong et al.
Xuemei Chen et al.
Background: Allergic bronchopulmonary aspergillosis/mycosis (ABPA/ABPM) is frequently misdiagnosed as pulmonary tuberculosis due to overlapping clinical and radiological features. ...
Effectiveness of FF/UMEC/VI versus ICS/LABA in Patients with Uncontrolled Asthma Treated in Routine Clinical Practice (PERFORM): A Pragmatic Randomized Controlled Trial [0.03%]
未控制哮喘患者常规临床治疗中使用FF/UMEC/VI与ICS/LABA的疗效:一项实用随机对照试验(PERFORM)
Erika Penz,Stephen G Noorduyn,Alison C Moore et al.
Erika Penz et al.
Purpose: Asthma guidelines recommend stepwise escalation of inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) therapy, yet many patients remain uncontrolled. Randomized controlled trials (RCTs) show that single-in...
Mortality Among Adults with Subspecialist-Treated Severe Asthma: A Descriptive Analysis from the Observational CHRONICLE Study [0.03%]
基于观察性CHRONICLE研究的成人严重哮喘患者死亡率的描述性分析
Njira L Lugogo,Jennifer Trevor,Joseph D Spahn et al.
Njira L Lugogo et al.
Purpose: There are limited recent data assessing all-cause mortality for US patients with severe asthma. This descriptive analysis evaluated all-cause mortality in a real-world cohort of US adults with subspecialist-treat...
Persistence and Reasons for Discontinuation of Subcutaneous Immunotherapy in Children with Dust Mite Allergy: A Real-World Cohort from Hangzhou, China [0.03%]
中国杭州真实世界过敏原免疫治疗队列中尘螨致敏儿童皮下免疫治疗的依从性及中断原因分析
Zhenghong Song,Jing He,Shuxian Li et al.
Zhenghong Song et al.
Objective: To investigate the present state of adherence to subcutaneous specific immunotherapy (SCIT) in children sensitized to dust mites, explore the factors contributing to the cessation of SCIT in this demographic, a...
Assessment of Inhaled Corticosteroid Adherence in Adults with Severe Asthma Receiving Biologic Therapy: A Retrospective Observational Study [0.03%]
接受生物制剂治疗的成人严重哮喘患者吸入皮质类固醇依从性的评估:一项回顾性观察研究
Gökten Bulut,Derya Aydın
Gökten Bulut
Background: Inhaled corticosteroids (ICS) remain the cornerstone of long-term asthma management. However, adherence to inhaled therapy is frequently suboptimal, even among patients with severe asthma. Biologic therapies s...
Drug Patterns and Economic Costs Among Patients with Hereditary Angioedema [0.03%]
遗传性血管水肿患者的药物使用模式和经济成本
Emily Kutrieb,Derek Weycker,Montserrat Vera-Llonch et al.
Emily Kutrieb et al.
Background/objectives: This study explored real-world patterns of subcutaneous (SC) long-term prophylaxis (LTP), prescriptions for on-demand treatment (ODT), and treatment-related expenditures among patients with heredita...
Prognostic Predictors of Bronchial Thermoplasty for Symptom Control in Severe Asthma [0.03%]
支气管热成形术控制重度哮喘症状的预后预测因素
Jia Pan,Ming-Lu Zhong,Xiao-Yi Pan et al.
Jia Pan et al.
Purpose: To explore the clinical biomarkers that predict therapeutic response to bronchial thermoplasty (BT) in severe asthma. Patients and methods: ...
Stability of Type 2 Inflammation in a 12-Year Adult-Onset Asthma Follow-Up Study [0.03%]
成人起病哮喘长达12年的随访研究中2型炎症的稳定性
Ella Flinkman,Iida Vähätalo,Leena E Tuomisto et al.
Ella Flinkman et al.
Purpose: To assess the stability of T2 inflammation and clinical features associated with high or low T2 markers in adult-onset asthma. Patients and metho...
Clinical Remission in Patients with Severe Eosinophilic Asthma - A Single-Arm Observational Study with Benralizumab [0.03%]
严重嗜酸性粒细胞哮喘患者临床缓解的单组观察研究——贝拉西珠单抗治疗效果
Nikolay Pavlov,Pierre-Olivier Bridevaux,Peter Jandus et al.
Nikolay Pavlov et al.
Purpose: To evaluate clinical remission rates and its individual components in patients with severe eosinophilic asthma treated with benralizumab, and to explore predictors of clinical remission using subgroup analyses by...