Step-down therapy in well-controlled asthmatic patients using salmeterol xinafoate/fluticasone propionate combination therapy [0.03%]
加布地奈德/Formoterol与氟替卡松/Salmeterol联合治疗控制良好的哮喘患者的降级疗法
Kazuya Horiuchi,Keita Kasahara,Yusuke Kuroda et al.
Kazuya Horiuchi et al.
Purpose: A combination therapy with inhaled corticosteroid (ICS) and a long-acting β agonist (LABA) is the standard treatment for asthmatic patients, and step-down treatment is recommended once control has been achieved....
Ayse Bilge Ozturk,Sinem Iliaz
Ayse Bilge Ozturk
Little is known about the features of asthma and allergy in the elderly. A significant number of elderly patients with asthma have uncontrolled and severe asthma. This review aims to provide an analysis of the literature on the assessment a...
Nasal polyps in patients with asthma: prevalence, impact, and management challenges [0.03%]
伴发哮喘患者的鼻息肉的患病率、影响及治疗挑战
Cristobal Langdon,Joaquim Mullol
Cristobal Langdon
Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) often have coexisting asthma under the concept of "United Airway Disease", being the combination of both diseases, which is one of the most challenging phenotypes to treat. Alt...
Aspirin-exacerbated respiratory disease: pathophysiological insights and clinical advances [0.03%]
阿司匹林加重呼吸道疾病：病理生理学见地和临床进展
John W Steinke,Jeff M Wilson
John W Steinke
Asthma and chronic rhinosinusitis are heterogeneous airway diseases of the lower and upper airways, respectively. Molecular and cellular studies indicate that these diseases can be categorized into unique endotypes, which have therapeutic i...
The asthma-COPD overlap syndrome: how is it defined and what are its clinical implications? [0.03%]
哮喘-COPD重叠综合征的定义及其临床意义是什么？
Maarten van den Berge,René Aalbers
Maarten van den Berge
It is increasingly recognized that both asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases with a large inter-individual variability with respect to their clinical expression, disease progression, and respons...
Antonella Cianferoni
Antonella Cianferoni
Triticum aestivum (bread wheat) is the most widely grown crop worldwide. In genetically predisposed individuals, wheat can cause specific immune responses. A food allergy to wheat is characterized by T helper type 2 activation which can res...
Predicting frequent asthma exacerbations using blood eosinophil count and other patient data routinely available in clinical practice [0.03%]
基于临床实践中的常规患者数据预测哮喘频繁急性发作的可能性
David Price,Andrew M Wilson,Alison Chisholm et al.
David Price et al.
Purpose: Acute, severe asthma exacerbations can be difficult to predict and thus prevent. Patients who have frequent exacerbations are of particular concern. Practical exacerbation predictors are needed for these patients...
Erratum: Morning and evening efficacy evaluation of rupatadine (10 and 20 mg), compared with cetirizine 10 mg in perennial allergic rhinitis: a randomized, double-blind, placebo-controlled trial [Corrigendum] [0.03%]
雷普塔蒂宁(10毫克和20毫克)早上服用和晚上服用对常年性过敏性鼻炎的疗效与西替利嗪10mg及安慰剂对照的随机双盲临床试验的勘误说明[ Corrections ]
[This corrects the article on p. 27 in vol. 4, PMID: 21698213.].
Published Erratum
Journal of asthma and allergy. 2015 Dec 17:8:135-7. DOI:10.2147/JAA.S100411 2015
The past, present, and future of monoclonal antibodies to IL-5 and eosinophilic asthma: a review [0.03%]
IL-5和嗜酸细胞性哮喘单克隆抗体的过去、现在和未来：综述
Megan F Patterson,Larry Borish,Joshua L Kennedy
Megan F Patterson
Asthma is a heterogeneous syndrome that might be better described as a constellation of phenotypes or endotypes, each with distinct cellular and molecular mechanisms, rather than as a singular disease. One of these phenotypes is eosinophili...
Jeanne M Lomas,Kirsi M Järvinen
Jeanne M Lomas
The prevalence of peanut and tree nut allergy in the USA has increased, especially in the pediatric population. Nut allergy remains the leading cause of fatal anaphylactic reactions. Management of anaphylaxis includes not only treatment of ...