Network Pharmacology of Natural Polyphenols for Stroke: A Bioinformatic Approach to Drug Design [0.03%]
网络药理学在天然多酚抗脑卒中研究中的应用及基于生物信息的方法学探索
Sudakshina Dutta,Arunkumar Subramanian,Vinoth Kumarasamy et al.
Sudakshina Dutta et al.
Background: Globally, stroke is a major contributor to disability and a leading cause of death. Stroke is more frequent in underdeveloped countries, where ischemic stroke is one of the most common kinds. Therefore, it is ...
LAMP5, One of Four Genes Related to Oxidative Stress That Predict Biochemical Recurrence-Free Survival, Promotes Proliferation and Invasion in Prostate Cancer [Retraction] [0.03%]
与氧化应激有关的四个基因之一，LAMP5可预测无生化复发生存率，促进前列腺癌的增殖和侵袭[缩回]
[This retracts the article DOI: 10.2147/AABC.S489131.]. © 2025 Dove Medical Press.
Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products [0.03%]
来源于天然产物的红麻生物碱胆碱酯酶抑制剂虚拟筛选、毒性评价及药代动力学性质研究
Afri Permana,Abd Wahid Rizaldi Akili,Ari Hardianto et al.
Afri Permana et al.
Purpose: Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited treatment options, necessitating the development of safer and more effective therapies. The potential of alkaloids derived from th...
Non-Invasive Cancer Detection Using Blood Test and Predictive Modeling Approach [0.03%]
基于血液检测和预测模型的无创癌症检测方法
Ahmad S Tarawneh,Ahmad K Al Omari,Enas M Al-Khlifeh et al.
Ahmad S Tarawneh et al.
Purpose: The incidence of cancer, which is a serious public health concern, is increasing. A predictive analysis driven by machine learning was integrated with haematology parameters to create a method for the simultaneou...
Recent Applications of Artificial Intelligence in Discovery of New Antibacterial Agents [0.03%]
人工智能在新型抗菌剂发现中的最新应用
Youcef Bagdad,Maria A Miteva
Youcef Bagdad
Antimicrobial resistance (AMR) represents today a major challenge for global public health, compromising the effectiveness of treatments against a multitude of bacterial infections. In recent decades, artificial intelligence (AI) has emerge...
LAMP5, One of Four Genes Related to Oxidative Stress That Predict Biochemical Recurrence-Free Survival, Promotes Proliferation and Invasion in Prostate Cancer [0.03%]
LAMP5促进前列腺癌的增殖和侵袭，在四个与氧化应激相关的基因中，可预测生化无复发生存期
Peiqiang Wu,Jianlei Zhang,Li Guo et al.
Peiqiang Wu et al.
Background: Prostate cancer (PCa) development largely depends on increased levels of oxidative stress (OS) and a deficient anti-oxidative system. Identifying genes associated with oxidative stress is critical in order to ...
Investigating the Potency of Erythrina‒Derived Flavonoids as Cholinesterase Inhibitors and Free Radical Scavengers Through in silico Approach: Implications for Alzheimer's Disease Therapy [0.03%]
基于计算方法研究erythrina属植物中黄酮类化合物的乙酰胆碱酯酶抑制及自由基清除活性：对阿尔茨海默症治疗的意义
Abd Wahid Rizaldi Akili,Nisrina Azizah Thurfah,Ari Hardianto et al.
Abd Wahid Rizaldi Akili et al.
Purpose: This study aimed to evaluate the potency of 471 flavonoids from the genus Erythrina as potential acetylcholinesterase (AChE) inhibitors and free radical scavengers through computational studies to develop Alzheim...
Employing Hexahydroquinolines as Pf CDPK4 Inhibitors to Combat Malaria Transmission: An Advanced Computational Approach [0.03%]
采用六氢喹啉作为Pf CDPK4抑制剂以对抗疟疾传播的高级计算方法
Gbolahan O Oduselu,Oluwadunni F Elebiju,Temitope A Ogunnupebi et al.
Gbolahan O Oduselu et al.
Background: Existing antimalarial drugs primarily target blood-stage parasites, but there is a need for transmission-blocking drugs to combat malaria effectively. Plasmodium falciparum Calcium-dependent Protein Kinase 4 (...
Toward Understanding the Anticancer Activity of the Phytocompounds from Eugenia uniflora Using Molecular Docking, in silico Toxicity and Dynamics Studies [0.03%]
基于分子对接、计算机毒性及动力学研究的肾茶茋抗肿瘤活性机制探讨
Pallab Kar,Ayodeji O Oriola,Adebola O Oyedeji
Pallab Kar
Background: The Surinam cherry, Eugenia uniflora belongs to the family Myrtaceae, an edible fruit-bearing medicinal plant with various biological properties. Several anticancer studies have been conducted on its essential...
Bioinformatics Study of Flavonoids From Genus Erythrina As Ace2 inhibitor Candidates For Covid-19 Treatment [0.03%]
从 erythrina 属中生物信息学研究作为 ACE2 抑制剂的黄酮类化合物以用于新冠治疗
Tati Herlina,Abd Wahid Rizaldi Akili,Vicki Nishinarizki et al.
Tati Herlina et al.
Purpose: This study aimed to screen potential drug candidates from the flavonoids of the genus Erythrina for the Corona Virus Disease 2019 (COVID-19) treatment. ...