Tryptophan and Biogenic Amines in the Differentiation and Quality of Honey [0.03%]
色氨酸和生物胺在蜂蜜的分类和质量中的作用
Cristine Vanz Borges,Aline Nunes,Vladimir Eliodoro Costa et al.
Cristine Vanz Borges et al.
Honey is a natural product with beneficial properties to health and has different characteristics depending on the region of production and collection, flowering, and climate. The presence of precursor amino acids of- and biogenic amines ca...
Plasma Kynurenine: A Promising Marker for the Assessment of Renal Functions [0.03%]
血浆犬尿酸可能成为肾功能损伤的生物标志物
Fatimah Brekdar,Muhammed Imad Khayat,Afraa Zrieki
Fatimah Brekdar
Background: Chronic kidney disease (CKD) is a worldwide issue due to the high prevalence and the serious complications, including death. Kidney functions are routinely evaluated by measuring creatinine levels, which are i...
Alterations in Tryptophan Metabolism Affect Vascular Functions: Connected to Ageing Population Vulnerability to COVID-19 Infection? [0.03%]
色氨酸代谢改变影响血管功能：与年龄人口易感染新冠肺炎的脆弱性有关吗？
Arehally M Mahalakshmi,Shasthara Paneyala,Bipul Ray et al.
Arehally M Mahalakshmi et al.
The Kynurenine Pathway and Polycystic Ovary Syndrome: Inflammation as a Common Denominator [0.03%]
犬尿酸途径与多囊卵巢综合征：炎症作为共同因素
Filip Jovanovic,Aboorva Sudhakar,Nebojsa Nick Knezevic
Filip Jovanovic
Polycystic ovary syndrome (PCOS) is a complex metabolic disorder commonly seen in females of reproductive age. The pathophysiology of PCOS is multifactorial and includes dysfunction in ovarian steroidogenesis and folliculogenesis, impaired ...
Loss of Indoleamine-2,3-Dioxygenase-1 (IDO1) in Knockout Mice Does Not Affect the Development of Skin Lesions in the Imiquimod-Induced Mouse Model of Psoriasis [0.03%]
诱导型一氧化氮合酶-1(IDO1)敲除小鼠在咪喹莫德诱导的银屑病小鼠模型中对皮肤病变的发展没有影响
Vivek Choudhary,Etsubdenk Ajebo,Rawipan Uaratanawong et al.
Vivek Choudhary et al.
Indoleamine-2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan resulting in tryptophan depletion and the accumulation of catabolites such as kynurenine. The expression/activity of IDO in various cells, including macrophages ...
Kynurenine Pathway in Chronic Kidney Disease: What's Old, What's New, and What's Next? [0.03%]
慢性肾脏病中的犬尿氨酸途径：哪些是已知的，哪些是新的，以及未来的研究方向是什么？
Adrian Mor,Bartlomiej Kalaska,Dariusz Pawlak
Adrian Mor
Impaired kidney function and increased inflammatory process occurring in the course of Chronic Kidney Disease (CKD) contribute to the development of complex amino-acid alterations. The essential amino-acid tryptophan (TRP) undergoes extensi...
Social and Biological Parameters Involved in Suicide Ideation During the COVID-19 Pandemic: A Narrative Review [0.03%]
新冠疫情下自杀想法相关的社会及生物学参数：综述性文章
Chenthamara Dhrisya,Murugan Prasathkumar,Robert Becky et al.
Chenthamara Dhrisya et al.
Fear is an indispensable characteristic of any infectious disease, and the alarm will be further amplified when the infection spreads uncontrollable, unpredictable, and global. The novel corona virus (SARS CoV-2) lead Covid-19, has been dec...
David B Ramsden,Rosemary H Waring,David J Barlow et al.
David B Ramsden et al.
Over the past decade, the roles of nicotinamide N-methyltransferase and its product 1-methyl nicotinamide have emerged from playing merely minor roles in phase 2 xenobiotic metabolism as actors in some of the most important scenes of human ...
Intestinal Dysbiosis, the Tryptophan Pathway and Nonalcoholic Steatohepatitis [0.03%]
肠道菌群失调、色氨酸代谢途径与非酒精性脂肪肝病
Jiezhong Chen,Luis Vitetta,Jeremy D Henson et al.
Jiezhong Chen et al.
Non-alcoholic fatty liver disease (NAFLD) progresses from simple steatosis to steatohepatitis (NASH), which may then progress to the development of cirrhosis and hepatocarcinoma. NASH is characterized by both steatosis and inflammation. Con...
Kynurenine and Anthranilic Acid in the Peritoneum Correlate With the Stage of Gastric Cancer Disease [0.03%]
胃癌患者腹水中犬尿酸和邻氨基苯甲酸的浓度与肿瘤负荷相关性研究
Katarzyna Gęca,Karol Rawicz-Pruszyński,Radosław Mlak et al.
Katarzyna Gęca et al.
Background: This study aimed to assess the importance of selected kynurenines measured in peritoneal fluid, lavage washings, and blood serum in patients with advanced gastric cancer (GC) based on the clinical and patholog...