IBS May Have a Causal Effect on Increased Tryptophan Metabolites Levels: Insights from a Bidirectional Two-Sample Mendelian Randomization Study [0.03%]
基于双向孟德尔随机化研究的肠易激综合征可能对增加的色氨酸代谢物水平具有因果效应：见解
Peilin Cheng,Ruzhen Jia,Bingjie Jin et al.
Peilin Cheng et al.
Background: Irritable Bowel Syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by abdominal pain and altered bowel habits. Tryptophan, an essential amino acid derived from dietary proteins, can...
Preoperative Peripheral Blood Serotonin and Kynurenine Levels Are Associated With Oncological Outcomes in Glioblastoma IDH-wt Patients [0.03%]
术前外周血5-羟色胺和犬尿氨酸水平与IDH-wt型胶质母细胞瘤患者的肿瘤预后相关
Silvia Snider,Filippo Gagliardi,Pierfrancesco De Domenico et al.
Silvia Snider et al.
Background: In recent years, there has been a growing interest in exploring the potential contribution of tryptophan (TRP) metabolism via the kynurenine (KP) and serotonin (SP) pathways in Glioblastoma (GBM) biology. This...
Relationship Between Psychological Stress Scores and Urinary 5-HT Levels Over Time Under Psychological Stress [0.03%]
心理应激下心理应激评分与尿液5-羟色胺水平变化的关联分析
Tadayuki Iida,Yasuhiro Ito,Susumu Murayama et al.
Tadayuki Iida et al.
Background: Biomarkers for psychological stress have been examined and the "gut-microbiota-brain axis" is currently attracting attention. An intervention study reported improvements in both the intestinal environment and ...
Baseline Inflammation but not Exercise Modality Impacts Exercise-induced Kynurenine Pathway Modulation in Persons With Multiple Sclerosis: Secondary Results From a Randomized Controlled Trial [0.03%]
基线炎症但不是运动形式影响多发性硬化症患者运动诱导的犬尿氨酸通路调节：随机对照试验的次要结果
Marie Kupjetz,Nadine Patt,Niklas Joisten et al.
Marie Kupjetz et al.
Background: The kynurenine pathway (KP) is an important hub in neuroimmune crosstalk that is dysregulated in persons with multiple sclerosis (pwMS) and modulated by exercise in a modality-specific manner. ...
Erratum to 'Dietary Hesperidin Suppresses Lipopolysaccharide-Induced Inflammation in Male Mice' [0.03%]
他莫昔芬通过表观遗传调控介导的长链非编码RNA在乳腺癌中作用机制的研究 Erratum
[This corrects the article DOI: 10.1177/11786469221128697.]. © The Author(s) 2024.
Investigations Towards Tryptophan Uptake and Transport Across an In Vitro Model of the Oral Mucosa Epithelium [0.03%]
色氨酸经口腔粘膜上皮模型吸收和转运的体外研究
Grace C Lin,Julia Tevini,Lisa Mair et al.
Grace C Lin et al.
Tryptophan is an essential amino acid and plays an important role in several metabolic processes relevant for the human health. As the main metabolic pathway for tryptophan along the kynurenine axis is involved in inflammatory responses, ch...
The Tryptophan Metabolite Indole-3-Propionic Acid Raises Kynurenic Acid Levels in the Rat Brain In Vivo [0.03%]
色氨酸代谢产物吲哚-3-丙酸在活体大鼠脑内提高犬尿酸水平
Korrapati V Sathyasaikumar,Tonali Blanco-Ayala,Yiran Zheng et al.
Korrapati V Sathyasaikumar et al.
Alterations in the composition of the gut microbiota may be causally associated with several brain diseases. Indole-3-propionic acid (IPrA) is a tryptophan-derived metabolite, which is produced by intestinal commensal microbes, rapidly ente...
Periconceptional Non-medical Maternal Determinants Influence the Tryptophan Metabolism: The Rotterdam Periconceptional Cohort (Predict Study) [0.03%]
孕前非医学的母体因素影响色氨酸代谢：鹿特丹孕前队列（预测研究）
Sofie Km van Zundert,Lenie van Rossem,Mina Mirzaian et al.
Sofie Km van Zundert et al.
Background: The vital role of the maternal tryptophan (TRP) metabolism in maternal health and pregnancy is well established. However, non-medical maternal determinants influencing the TRP metabolism have been poorly inves...
Sagar Vyavahare,Pankaj Ahluwalia,Sonu Kumar Gupta et al.
Sagar Vyavahare et al.
Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is crucial in maintaining the skeletal system. Our study focuses on encapsulating the role of AhR in bone biology and identifying novel signaling pathways in musculos...
A Review of the Evidence for Tryptophan and the Kynurenine Pathway as a Regulator of Stem Cell Niches in Health and Disease [0.03%]
色氨酸和犬尿酸途径作为干细胞生态位的调节因子在健康与疾病中的证据综述
Benjamin Sebastian Summers,Sarah Thomas Broome,Tsz Wai Rosita Pang et al.
Benjamin Sebastian Summers et al.
Stem cells are ubiquitously found in various tissues and organs in the body, and underpin the body's ability to repair itself following injury or disease initiation, though repair can sometimes be compromised. Understanding how stem cells a...