Protective Effects of Acridocarpus smeathmannii (DC.) Guill. & Perr. Root Extract against Phenylhydrazine-Induced Haematotoxicity, Biochemical Changes, and Oxidative Stress in Rats [0.03%]
防己科smeahtmannn氏胶结草根对肼诱导的大鼠血液毒性的保护作用、生化变化及氧化应激反应
Oluwafemi Ezekiel Kale,Olufunsho Awodele,Abidemi James Akindele
Oluwafemi Ezekiel Kale
Several strategies for discovering drugs from unexplored natural products continue to strengthen research and development with current commercial evidence supporting their applications. We assessed the effects of the hydroethanolic extract ...
A Solo Dance or a Tango? [0.03%]
单人舞还是探戈？
Yulin Wan,Shanshan An,Yanchao Zhou et al.
Yulin Wan et al.
Previous studies have identified genetic factors and Epstein-Barr virus underlying nasopharyngeal carcinoma. A hypothesis postulated that the local buildup of HCl, mediated by hydrogen bond donors and acceptors and basic amino acids, causes...
Shanshan An,Jiaming Zhang,Yuchuan Wang et al.
Shanshan An et al.
N 6-Methyladenosine methylations and demethylations are associated with a number of human diseases. A chemical and biochemical perspective can complement the biological view of the epigenetic mechanism. The orbital of imino nitrogen and ni...
Cellular States and Secondary Chemical Bonding: A Biochemical View of Major Human Diseases [0.03%]
细胞状态和次级化学键合：重大人类疾病生化原因的新观点
Yulin Wan,Jiaming Zhang,Xiaoxia Li et al.
Yulin Wan et al.
Nasopharyngeal carcinoma is prevalent in hot and humid areas such as south coastal China and Southeast Asia, but not in the non-coastal southern Chinese Yunnan Province. Secondary chemical bonding may underlie such phenomena. Cancer may be ...
Aerococcus urinae and Globicatella sanguinis Persist in Polymicrobial Urethral Catheter Biofilms Examined in Longitudinal Profiles at the Proteomic Level [0.03%]
蛋白质组学纵向分析尿道导管生物膜中的Aerococcus urinae和Globicatella sanguinis
Yanbao Yu,Tamara Tsitrin,Shiferaw Bekele et al.
Yanbao Yu et al.
Aerococcus urinae (Au) and Globicatella sanguinis (Gs) are gram-positive bacteria belonging to the family Aerococcaceae and colonize the human immunocompromised and catheterized urinary tract. We identified both pathogens in polymicrobial u...
A High Creatine Kinase Concentration Might Be a Sign of McArdle Disease in Patient With Type 1 Diabetes [0.03%]
糖尿病患者高 creatine 情况可能是 McArdle 病的标志
Kader Ugur,Yakup Aydogan,Abdurrahman Akgun et al.
Kader Ugur et al.
Type 1 diabetes (the pancreas producing little or no insulin) is usually diagnosed in children and young adults and was previously known as juvenile diabetes. McArdle disease is a common metabolic defect caused by an inherited deficit of my...
The Role of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Nervous System [0.03%]
胰岛素样生长因子及其结合蛋白在神经系统中的作用
Moira S Lewitt,Gary W Boyd
Moira S Lewitt
The insulin-like growth factors (IGF-I and IGF-II) and their receptors are widely expressed in nervous tissue from early embryonic life. They also cross the blood brain barriers by active transport, and their regulation as endocrine factors...
Connexin-43 Enhances the Redesigned Cytosine Deaminase Activity for Suicide Gene Therapy in Human Breast Cancer Cells [0.03%]
缝隙蛋白43增强改良版胞苷脱氨酶 suicide基因治疗在人类乳腺癌细胞中的作用
Asif Raza,Siddhartha Sankar Ghosh
Asif Raza
Background: Escherichia coli cytosine deaminase (CD) converts 5-fluorocytosine (5-FC), a prodrug, into 5-fluorouracil (5-FU), a chemotherapeutic drug. However, the poor binding affinity of CD towards 5-FC as compared to t...
Aerobic Respiration: Criticism of the Proton-centric Explanation Involving Rotary Adenosine Triphosphate Synthesis, Chemiosmosis Principle, Proton Pumps and Electron Transport Chain [0.03%]
有氧呼吸：对旋转生成三磷酸腺苷、质子泵和电子传递链的 proton-centric 解释的批评
Kelath Murali Manoj
Kelath Murali Manoj
The acclaimed explanation for mitochondrial oxidative phosphorylation (mOxPhos, or cellular respiration) is a deterministic proton-centric scheme involving four components: Rotary adenosine triphosphate (ATP)-synthesis, Chemiosmosis princip...
Keith J Stine
Keith J Stine
Nanoporous gold (referred to as np-Au or NPG) has emerged over the past 10 years as a new support for enzyme immobilization. The material has appealing features of ease of preparation, tunability of pore size, high surface to volume ratio, ...