EPAS1 and VEGFA Polymorphisms Modulate COPD Susceptibility in a High-Altitude Population: A Case-Control Study [0.03%]
Lin Lin,Yi Zhang,Xiang Fu et al.
Lin Lin et al.
Background: The onset and progression of Chronic Obstructive Pulmonary Disease (COPD) are influenced by both environmental and genetic factors. Persistent hypoxia at high altitudes is a major environmental stressor. Under...
Smoking-Attributable Burden of Chronic Obstructive Pulmonary Disease from 1990 to 2021: Temporal Trends and Evidence from the Global Burden of Disease Study [0.03%]
1990至2021年慢性阻塞性肺疾病的吸烟归因负担：全球疾病负担研究的 temporal trends 和证据
Tianqi Ma,Xianfeng Yue,Shuyu Rong et al.
Tianqi Ma et al.
Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability worldwide, with smoking being the primary contributor. This study aims to assess the temporal and spatial trends in the...
Genetically Predicted Use of Common Analgesics and Risk of Chronic Obstructive Pulmonary Disease: A Bidirectional Mendelian Randomization Study [0.03%]
基于 mendelian 随机化研究的遗传预测的常用止痛药使用与慢性阻塞性肺疾病风险的关系
Guojun Chen,Wanhui You
Guojun Chen
Background: Observational studies suggest a link between common analgesic use and chronic obstructive pulmonary disease (COPD), but causality is unclear. This study aimed to investigate the bidirectional causal relationsh...
Genetic and Molecular Interconnections Between Chronic Obstructive Pulmonary Disease and Osteoporosis: Insights from Single-Cell and Mendelian Randomization Analyses [0.03%]
慢性阻塞性肺疾病与骨质疏松症的遗传和分子相互作用：单细胞及孟德尔随机化分析的新见解
Cheng Xue,Pengcheng Liu,Siguo Zhao et al.
Cheng Xue et al.
Background: Chronic obstructive pulmonary disease (COPD) and osteoporosis are common comorbid conditions, both of which impose a significant health burden. This research employs single-cell data and Mendelian randomizatio...
COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications [0.03%]
慢性阻塞性肺疾病-肺癌共病：机制见解及精准治疗意义
Yajuan He,Beili Liu,Wenjun Li et al.
Yajuan He et al.
Background: Chronic obstructive pulmonary disease (COPD) and lung cancer frequently coexist, constituting a clinically consequential comorbidity with major implications for precision medicine. ...
PPARA Gene Polymorphisms and Their Association with COPD in Tibetan and Han Populations from Gansu, China [0.03%]
中国甘肃藏族和汉族人群PPARA基因多态性与慢阻肺关联研究
Renjie Gao,Miao Zhang,Yangjie Zhang et al.
Renjie Gao et al.
Background: Chronic Obstructive Pulmonary Disease (COPD) is influenced by both genetic and environmental factors, with chronic hypoxia playing a pivotal role in its pathogenesis. Peroxisome proliferator-activated receptor...
Longitudinal Spirometric Trajectory from Normal Lung Function to PRISm and COPD in a Population-Based Korean Cohort [0.03%]
基于韩国人群的队列研究中的肺通气功能正常值到PRISm和COPD的纵向肺功能轨迹分析
Sun Young Kang,Sanghyun Roh,In Hwan Yeo et al.
Sun Young Kang et al.
Background: Chronic obstructive pulmonary disease (COPD) develops through heterogeneous lung-function trajectories, but the longitudinal role of preserved ratio impaired spirometry (PRISm) in progression toward COPD remai...
Small Airway Disease in Pre-COPD and Early COPD: Insights Into the Pulmonary "Silent Zone" [0.03%]
肺部"沉默区"的气道病变：慢性阻塞性肺疾病前期和早期患者的支气管炎与小气道疾病的特征研究
Jingli Li,Lingjing Liu,Jixian Tang et al.
Jingli Li et al.
Chronic obstructive pulmonary disease (COPD) is increasingly recognized as a life-course disorder with origins rooted in early-life insults. However, the current diagnostic reliance on the FEV1/FVC < 0.7 threshold often fails to capture the...
From Weight Loss to Standardized Sarcopenia Assessment: A Multi-Database Bibliometric Study of COPD with Sarcopenia (2005-2025) [0.03%]
从减重到肌肉减少症标准化评估：多数据库文献计量学研究(2005-2025年 sarcopenic慢性阻塞性肺疾病文献分析）
Hanyu Fang,Yiyuanzi Zhao,Jiaqi Wang et al.
Hanyu Fang et al.
Background: Chronic obstructive pulmonary disease (COPD) often coexists with sarcopenia, contributing to poorer exercise tolerance, quality of life, and prognosis. Although interest in this topic has increased, a comprehe...
Impact of Nutritional Status and Sarcopenia on Acute Exacerbation Risk in Stable Chronic Obstructive Pulmonary Disease: A Retrospective Cohort Study [0.03%]
营养状况和少肌症对慢性阻塞性肺病急性加重风险的影响：回顾性队列研究
Haitao Pan,Meiqin Wang,Xiangfei Chen et al.
Haitao Pan et al.
Background: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) drive disease progression and mortality. This study aims to investigate whether nutritional risk and sarcopenia independently predict (AECO...