Laurent Bréhélin
Laurent Bréhélin
In recent years, several machine learning (ML) approaches have been proposed to predict gene expression signal and chromatin features from the DNA sequence alone. These models are often used to deduce and, to some extent, assess putative ne...
Bioinformatic Annotation of Transposon DNA Processing Genes on the Long-Read Genome Assembly of Caenorhabditis elegan s [0.03%]
利用基因组测序组装结果对Caenorhabditis elegans转座子DNA加工基因进行生物信息学注释
Yukinobu Arata,Peter Jurica,Nicholas Parrish et al.
Yukinobu Arata et al.
Transposable elements (TEs) or transposons are thought to play roles in animal physiological processes, such as germline, early embryonic, and brain development, as well as aging. However, their roles have not been systematically investigat...
Variations in Furin SNPs, a Major Concern of SARS-CoV-2 Susceptibility Among Different Populations: An In- Silico Approach [0.03%]
不同人群易感SARS-CoV-2的FURIN基因多态性差异：一种基于计算机的方法
Md Nasir Uddin,Md Arzo Mia,Yasmin Akter et al.
Md Nasir Uddin et al.
COVID-19 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) had an adverse effect globally because it caused a global pandemic with several million deaths. This virus possesses spike protein that is cleaved or activated ...
The Alteration of Proteomic Profiles in Hippocampus of Type 2 Diabetic Mice Associated With Cognitive Impairment [0.03%]
与认知障碍相关II型糖尿病小鼠海马蛋白组分的改变
Yoottana Janthakhin,Sirikran Juntapremjit,Karin Hummel et al.
Yoottana Janthakhin et al.
Clinical and experimental studies have demonstrated that type 2 diabetes mellitus (T2DM) affects the brain structure and function, in particular the hippocampus, leading to cognitive impairments. However, the molecular mechanisms underlying...
Genome-Wide Tool for Sensitive de novo Identification and Visualisation of Interspersed and Tandem Repeats [0.03%]
一种全基因组工具，可从头敏感识别和可视化互穿插重复序列及串联重复序列
Ruslan Kalendar,Ulykbek Kairov
Ruslan Kalendar
Genomic repeats are functionally ubiquitous structural units found in all genomes. Studying these repeats of different origins is essential for understanding the evolution and adaptation of a given organism. These repeating patterns have ma...
Comprehensive Analysis of CRISPR-Cas Systems and Their Influence on Antibiotic Resistance in Salmonella enterica Strains [0.03%]
CRISPR-Cas系统及其对鼠伤寒沙门氏菌抗生素抗性影响的全面分析
Tina Fallah,Morvarid Shafiei
Tina Fallah
Salmonella enterica is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in S. enterica is still under inve...
Multi-epitope Based Peptide Vaccine Candidate Against Babesia Infection From Rhoptry-Associated Protein 1 (RAP-1) Antigen Using Immuno-Informatics: An In Silico Approach [0.03%]
基于免疫信息学的环形泰勒虫Rhoptry相关蛋白1（RAP-1）抗原多表位肽疫苗候选抗巴贝斯虫感染疫苗的体内研究
Samson Anjikwi Malgwi,Victoria T Adeleke,Matthew Adekunle Adeleke et al.
Samson Anjikwi Malgwi et al.
Objective: Babesiosis is a significant haemoparasitic infection caused by apicomplexan parasites of the genus Babesia. This infection has continuously threatened cattle farmers owing to its devastating effects on producti...
Prediction of Human Papillomavirus-Host Oncoprotein Interactions Using Deep Learning [0.03%]
基于深度学习的预测人类乳头瘤病毒-宿主致癌蛋白相互作用
Sheila Santa,Samuel Kojo Kwofie,Kwasi Agyenkwa-Mawuli et al.
Sheila Santa et al.
Background: Human papillomavirus (HPV) causes disease through complex interactions between viral and host proteins, with the PI3K signaling pathway playing a key role. Proteins like AKT, IQGAP1, and MMP16 are involved in ...
Comprehensive Analysis of the Influence of Technical and Biological Variations on De Novo Assembly of RNA-Seq Datasets [0.03%]
技术与生物变异对从头组装RNA测序数据集影响的全面分析
Gonzalez Sergio Alberto,Rivarola Maximo,Ribone Andres et al.
Gonzalez Sergio Alberto et al.
De novo assembly of transcriptomes from species without reference genome remains a common problem in functional genomics. While methods and algorithms for transcriptome assembly are continually being developed and published, the quality of ...
Exploring LDLR-APOB Interactions in Familial Hypercholesterolemia in the Vietnamese Population: A Protein-Protein Docking Approach [0.03%]
越南人群家族性高胆固醇血症中LDLR-APOB相互作用的探究：一种蛋白质对接方法
Ngoc-Thanh Kim,Doan-Loi Do,Mai-Ngoc Thi Nguyen et al.
Ngoc-Thanh Kim et al.
Atherosclerotic cardiovascular diseases (CVDs) are closely linked to factors such as familial hypercholesterolemia (FH), often caused by mutations in low-density lipoprotein receptor (LDLR) and apolipoprotein B (APOB). Through a comprehensi...