An improved approach for mapping quantitative trait Loci in a pseudo-testcross: revisiting a poplar mapping study [0.03%]
单假测交图谱构建的改进及模式植物黑杨的应用
Song Wu,Jie Yang,Youjun Huang et al.
Song Wu et al.
A pseudo-testcross pedigree is widely used for mapping quantitative trait loci (QTL) in outcrossing species, but the model for analyzing pseudo-testcross data borrowed from the inbred backcross design can only detect those QTLs that are het...
Inferring Transcriptional Interactions by the Optimal Integration of ChIP-chip and Knock-out Data [0.03%]
整合ChIP-chip和剔除数据进行转录交互推断的最佳方法
Haoyu Cheng,Lihua Jiang,Maoying Wu et al.
Haoyu Cheng et al.
How to combine heterogeneous data sources for reliable prediction of transcriptional regulation is a challenge. Here we present an easy but powerful method to integrate Chromatin immunoprecipitation (ChIP)-chip and knock-out data. Since the...
Gromita: a fully integrated graphical user interface to gromacs 4 [0.03%]
Gromita：适用于 Gromacs 4 的完全集成的图形用户界面
Diamantis Sellis,Dimitrios Vlachakis,Metaxia Vlassi
Diamantis Sellis
Gromita is a fully integrated and efficient graphical user interface (GUI) to the recently updated molecular dynamics suite Gromacs, version 4. Gromita is a cross-platform, perl/tcl-tk based, interactive front end designed to break the comm...
Automated detection of conformational epitopes using phage display Peptide sequences [0.03%]
基于噬菌体展示肽序列的表位识别方法研究
Surendra S Negi,Werner Braun
Surendra S Negi
Background: Precise determination of conformational epitopes of neutralizing antibodies represents a key step in the rational design of novel vaccines. A powerful experimental method to gain insights on the physical chemi...
Predicting consensus structures for RNA alignments via pseudo-energy minimization [0.03%]
基于伪能量最小化的RNA序列一致性结构预测方法
Junilda Spirollari,Jason T L Wang,Kaizhong Zhang et al.
Junilda Spirollari et al.
Thermodynamic processes with free energy parameters are often used in algorithms that solve the free energy minimization problem to predict secondary structures of single RNA sequences. While results from these algorithms are promising, an ...
Bioinformatics as a tool for assessing the quality of sub-cellular proteomic strategies and inferring functions of proteins: plant cell wall proteomics as a test case [0.03%]
作为亚细胞蛋白质组策略质量评估和推断植物细胞壁蛋白质功能的工具的生物信息学研究
Hélène San Clemente,Rafael Pont-Lezica,Elisabeth Jamet
Hélène San Clemente
Bioinformatics is used at three different steps of proteomic studies of sub-cellular compartments. First one is protein identification from mass spectrometry data. Second one is prediction of sub-cellular localization, and third one is the ...
B Knapp,W Schreiner
B Knapp
In the past years an increasing number of graphical user interfaces for Molecular Dynamics (MD) were presented and concomitantly, more and more Molecular Dynamics studies were published. With the easier application of MD software packages t...
Universal Features for the Classification of Coding and Non-coding DNA Sequences [0.03%]
用于编码和非编码DNA序列分类的通用特征
Nicolas Carels,Ramon Vidal,Diego Frías
Nicolas Carels
In this report, we revisited simple features that allow the classification of coding sequences (CDS) from non-coding DNA. The spectrum of codon usage of our sequence sample is large and suggests that these features are universal. The featur...
affyPara-a Bioconductor Package for Parallelized Preprocessing Algorithms of Affymetrix Microarray Data [0.03%]
AffyPara：一个用于同时处理AFFYMETRIX芯片数据算法的Bioconductor工具包
Markus Schmidberger,Esmeralda Vicedo,Ulrich Mansmann
Markus Schmidberger
Microarray data repositories as well as large clinical applications of gene expression allow to analyse several hundreds of microarrays at one time. The preprocessing of large amounts of microarrays is still a challenge. The algorithms are ...
Using the Multiple Analysis Approach to Reconstruct Phylogenetic Relationships among Planktonic Foraminifera from Highly Divergent and Length-polymorphic SSU rDNA Sequences [0.03%]
利用多重分析方法重建浮游有孔虫的高度分化和长度多态性SSU rDNA序列的系谱关系
Ralf Aurahs,Markus Göker,Guido W Grimm et al.
Ralf Aurahs et al.
The high sequence divergence within the small subunit ribosomal RNA gene (SSU rDNA) of foraminifera makes it difficult to establish the homology of individual nucleotides across taxa. Alignment-based approaches so far relied on time-consumi...