Daisuke Tominaga
Daisuke Tominaga
Time series of gene expression often exhibit periodic behavior under the influence of multiple signal pathways, and are represented by a model that incorporates multiple harmonics and noise. Most of these data, which are observed using DNA ...
Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows [0.03%]
泌乳奶牛乳腺退化过程中代谢、组织重塑、氧化应激和炎症途径的表达
Paola Piantoni,Ping Wang,James K Drackley et al.
Paola Piantoni et al.
Histological and functional changes associated with involution in the mammary gland are partly regulated by changes in gene expression. At 42 d postpartum, Holstein cows underwent a period of 5 d during which they were milked 1X daily until...
Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets [0.03%]
砷响应蛋白靶点的候选单核苷酸多态性标记
Raphael D Isokpehi,Hari H P Cohly,Matthew N Anyanwu et al.
Raphael D Isokpehi et al.
Arsenic is a toxic metalloid that causes skin cancer and binds to cysteine residues-a property that could be used to infer arsenic responsiveness of a target protein. Non-synonymous Single Nucleotide Polymorphisms (nsSNPs) result in amino a...
An Allergen Portrait Gallery: Representative Structures and an Overview of IgE Binding Surfaces [0.03%]
过敏原结构图谱：免疫球蛋白E结合面的概览及代表性结构
Catherine H Schein,Ovidiu Ivanciuc,Terumi Midoro-Horiuti et al.
Catherine H Schein et al.
Recent progress in the biochemical classification and structural determination of allergens and allergen-antibody complexes has enhanced our understanding of the molecular determinants of allergenicity. Databases of allergens and their epit...
Xiang-Ping Wang,Nigel G F Cooper
Xiang-Ping Wang
Background: Cytoplasmic polyadenylation element binding proteins (Cpebs) are a family of proteins that bind to defined groups of mRNAs and regulate their translation. While Cpebs were originally identified as important fe...
Normal Mode Flexible Fitting of High-Resolution Structures of Biological Molecules Toward SAXS Data [0.03%]
基于正常模式的柔性拟合法在生物大分子 SAXS 数据约束下解析其高分辨率结构的方法
Christian Gorba,Florence Tama
Christian Gorba
We present a method to reconstruct a three-dimensional protein structure from an atomic pair distribution function derived from the scattering intensity profile from SAXS data by flexibly fitting known x-ray structures. This method uses a l...
Insights into Protein Sequence and Structure-Derived Features Mediating 3D Domain Swapping Mechanism using Support Vector Machine Based Approach [0.03%]
基于支持向量机方法介导三维结构交换机制的蛋白质序列及结构衍生特征的分析
Khader Shameer,Ganesan Pugalenthi,Krishna Kumar Kandaswamy et al.
Khader Shameer et al.
3-dimensional domain swapping is a mechanism where two or more protein molecules form higher order oligomers by exchanging identical or similar subunits. Recently, this phenomenon has received much attention in the context of prions and neu...
A plausible role for the presence of internal shine-dalgarno sites [0.03%]
内部 Shine-Dalgarno 序列的潜在作用
Lalit Ponnala
Lalit Ponnala
The presence of nucleotide hybridization between the 3' end of 16S rRNA and mRNA sequence upstream of the start codon is well known in bacteria. In this paper, we detect the presence of such hybridization sites inside the coding regions of ...
Effect of diet supplementation on the expression of bovine genes associated with Fatty Acid synthesis and metabolism [0.03%]
日粮补充对奶牛脂肪酸合成和代谢相关基因表达的影响
Sandeep J Joseph,Kelly R Robbins,Enrique Pavan et al.
Sandeep J Joseph et al.
Conjugated linoleic acids (CLA) are of important nutritional and health benefit to human. Food products of animal origin are their major dietary source and their concentration increases with high concentrate diets fed to animals. To examine...
Evolutionary Pattern of N-Glycosylation Sequon Numbers in Eukaryotic ABC Protein Superfamilies [0.03%]
真核ABC超家族糖基化位点的进化模式研究
R Shyama Prasad Rao,Ole Thomsen Buus,Bernd Wollenweber
R Shyama Prasad Rao
Many proteins contain a large number of NXS/T sequences (where X is any amino acid except proline) which are the potential sites of asparagine (N) linked glycosylation. However, the patterns of occurrence of these N-glycosylation sequons in...