Identification of Molecular Mechanisms of Ameloblastoma and Drug Repositioning by Integration of Bioinformatics Analysis and Molecular Docking Simulation [0.03%]
基于生物信息学分析和分子对接模拟的成釉细胞瘤分子机制识别与药物重定位研究
Suthipong Chujan,Nutsira Vajeethaveesin,Jutamaad Satayavivad et al.
Suthipong Chujan et al.
Background: Ameloblastoma (AM) is a benign tumor locally originated from odontogenic epithelium that is commonly found in the jaw. This tumor makes aggressive invasions and has a high recurrence rate. This study aimed to ...
Integrating Network Pharmacology and Molecular Docking Approach to Elucidate the Mechanism of Commiphora wightii for the Treatment of Rheumatoid Arthritis [0.03%]
基于网络药理学和分子对接的乳香治疗类风湿性关节炎作用机制研究
Mostafa A Abdel-Maksoud,Mostafa A Askar,Ibrahim Y Abdel-Rahman et al.
Mostafa A Abdel-Maksoud et al.
Background: Rheumatoid arthritis (RA) is considered a notable prolonged inflammatory condition with no proper cure. Synovial inflammation and synovial pannus are crucial in the onset of RA. The "tumor-like" invading proli...
Investigating the Antimicrobial Effects of a Novel Peptide Derived From Listeriolysin S on S aureus, E coli, and L plantarum: An In Silico and In Vitro Study [0.03%]
一种新型.listerialysinS衍生肽类物质的抗菌作用:对.S.aureus、.E.coli和.L.plantarum的研究(基于体内和体外实验)
Mojgan Sarabi Nobakht,Kaveh Bazyar,Mohammad Sadegh Ghalyanchi Langeroudi et al.
Mojgan Sarabi Nobakht et al.
Aims: The emergence of antibiotic resistance is one of the most significant issues today. Modifying antimicrobial peptides (AMPs) can improve their effects. In this study, the active region of Listeriolysin S (LLS) as a p...
Genes Differentially Expressed Across Major Arteries Are Enriched in Endothelial Dysfunction-Related Gene Sets: Implications for Relative Inter-artery Atherosclerosis Risk [0.03%]
在主要动脉中差异表达的基因富含内皮功能障碍相关的基因集:对相对动脉粥样硬化的风险的意义
Paul A Brown
Paul A Brown
Atherosclerosis differs across major arteries. Although the biological basis is not fully understood, limited evidence of genetic differences has been documented. This study, therefore, was aimed to identify differentially expressed genes b...
Manal Mostafa Ali,Maha Medhat Hassan,M Zaki
Manal Mostafa Ali
Gait analysis serves as a critical diagnostic tool for identifying neurologic and musculoskeletal damage. Traditional manual analysis of motion data, however, is labor-intensive and heavily reliant on the expertise and judgment of the thera...
DENV-2 Outbreak Associated With Cosmopolitan Genotype Emergence in Western Brazilian Amazon [0.03%]
巴西西部亚马逊地区与城市型基因型出现有关的登革热2型疫情
Jessiane Rodrigues Ribeiro,Tárcio Peixoto Roca,Gleense Dos Santos Cartonilho et al.
Jessiane Rodrigues Ribeiro et al.
Background: Dengue virus (DENV) causes an important disease and directly affects public health, being the arbovirus that presents the highest number of infections and deaths in the Western Brazilian Amazon. This virus is ...
In Silico Identification and Characterization of Fatty Acid Desaturase (FAD) Genes in Argania spinosa L. Skeels: Implications for Oil Quality and Abiotic Stress [0.03%]
.Argania spinosa L. Skeels脂肪酸去饱和酶(FAD)基因的鉴定与表征:对油质和非生物胁迫的影响
Abdelmoiz El Faqer,Karim Rabeh,Mohammed Alami et al.
Abdelmoiz El Faqer et al.
Fatty acid desaturase (FAD) is the key enzyme that leads to the formation of unsaturated fatty acids by introducing double bonds into hydrocarbon chains, and it plays a critical role in plant lipid metabolism. However, no data are available...
Analysis of CENP-B Boxes as Anchor of Kinetochores in Centromeres of Human Chromosomes [0.03%]
人类染色体着丝粒kinetochore锚定位点CENP-B box序列分析研究
Fritz F Parl
Fritz F Parl
The kinetochore is a multiprotein structure that attaches at one end to DNA in the centromere and at the other end to microtubules in the mitotic spindle. By connecting centromere and spindle, the kinetochore controls the migration of chrom...
The Novel PTX3 Variant g.22645332G>T Is Strongly Related to Awassi and Hamdani Sheep Litter Size [0.03%]
新型PTX3基因变异体g.22645332G>T与Awassi和Hamdani绵羊的产仔数密切相关
Faris S Imran,Tahreer M Al-Thuwaini
Faris S Imran
The detection of polymorphisms in genes that control livestock reproduction could be highly beneficial for identifying and enhancing economic traits. One of these genes is pentraxin 3 (PTX3), which affects the reproduction of sheep. Therefo...
The Potential Role of Phytochemicals of Juniperus procera in the Treatment of Ovarian Cancer and the Inhibition of Human Topoisomerase II Alpha Activity [0.03%]
Juniperus procera植物化学成分在卵巢癌治疗和抑制人类拓扑异构酶IIα活性中的潜在作用
Ateeq A Al-Zahrani
Ateeq A Al-Zahrani
A variety of active chemicals found in medicinal plants can be used to develop new medications with few adverse effects. In vitro and in silico analyses were used to evaluate the anticancer properties of Juniperus procera fruit and leaf ext...