Use of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency [0.03%]
人蛋白C浓缩剂治疗严重先天性蛋白C缺乏患者的疗效研究
Sabine Kroiss,Manuela Albisetti
Sabine Kroiss
Protein C is one of the major inhibitors of the coagulation system that downregulate thrombin generation. Severe congenital protein C deficiency leads to a hypercoagulability state that usually presents at birth with purpura fulminans and/o...
Overview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins [0.03%]
静脉注射丙种球蛋白治疗慢性炎症性脱髓鞘多发性神经病的发病机制和疗效综述
Mohamed Mahdi-Rogers,Yusuf A Rajabally
Mohamed Mahdi-Rogers
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired heterogeneous disorder of immune origin affecting the peripheral nerves, causing motor weakness and sensory symptoms and signs. The precise pathophysiology of CIDP rema...
A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis [0.03%]
海藻萃取营养复方对膝关节炎患者软骨生成及疼痛影响的I/IIa期开放标记临床研究
Stephen P Myers,Joan OConnor,J Helen Fitton et al.
Stephen P Myers et al.
Background: Isolated fucoidans from brown marine algae have been shown to have a range of anti-inflammatory effects. Purpose: This pres...
Update on the treatment of gastrointestinal stromal tumors (GISTs): role of imatinib [0.03%]
胃肠间质瘤(GIST)治疗进展——伊马替尼的作用
Richard Quek,Suzanne George
Richard Quek
In the last decade a tremendous amount has been learned about the biology and treatment of gastrointestinal stromal tumor (GIST). Imatinib mesylate has revolutionized the treatment of metastatic GIST. In addition, the role of imatinib in lo...
Ahmed Gibreel,Siladitya Bhattacharya
Ahmed Gibreel
Recombinant human follicle stimulating hormone (rFSH) and luteinizing hormone (LH), also known as follitropin alpha and lutropin alpha, are manufactured by genetic engineering techniques which ensure high quality and batch to batch consiste...
Alfredomaria Lurati,Mariagrazia Marrazza,Katia Angela et al.
Alfredomaria Lurati et al.
Objective: To report side effects seen in a clinical cohort of patients aged >65 years with rheumatoid arthritis (RA) treated with the tumor necrosis factor-alpha TNF-alpha blocker etanercept and to compare the side effec...
New advances in the treatment of adult chronic immune thrombocytopenic purpura: role of thrombopoietin receptor-stimulating agents [0.03%]
成人慢性免疫性血小板减少症治疗新进展:血小板生成素受体激动剂的作用机制及临床价值
Ara Metjian,Charles S Abrams
Ara Metjian
Decades of basic science and clinical research have led to an increased understanding of the pathophysiology of immune thrombocytopenic purpura (ITP), the processes underlying thrombopoiesis, and the treatment of chronic ITP. Now, new agent...
Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug Effectiveness Review Project [0.03%]
艾那西普治疗类风湿性关节炎的有效性和安全性:俄勒冈药物效应评审项目的更新研究结果
Kylie Thaler,Divya V Chandiramani,Richard A Hansen et al.
Kylie Thaler et al.
Objective: To systematically review the general and comparative efficacy and safety of anakinra for rheumatoid arthritis. Methods: We s...
Hussein Tawbi,Neelima Nimmagadda
Hussein Tawbi
Malignant melanoma is a highly lethal disease unless detected early. Single-agent chemotherapy is well tolerated but is associated with very low response rates. Combination chemotherapy and biochemotherapy may improve objective response rat...
Local cytokines and clinical symptoms in children with allergic rhinitis after different treatments [0.03%]
不同治疗方法后过敏性鼻炎患儿局部细胞因子及临床症状的变化
Gesmar Rs Segundo,Fabíola A Gomes,Karla P Fernandes et al.
Gesmar Rs Segundo et al.
Background: Therapy for allergic rhinitis aims to control symptoms and improve the quality of life. The treatment of allergic rhinitis includes allergen avoidance, environmental controls, pharmacologic treatment, and spec...