Maria de Los Angeles Tejada,Kathleen Stolpe,Anne-Kristine Meinild et al.
Maria de Los Angeles Tejada et al.
Slick and Slack high-conductance potassium channels have been recently discovered, and are found in the central nervous system and in the heart. Both channels are activated by Na(+) and Cl(-), and Slick channels are also inhibited by adenos...
Anti-tumor necrosis factor (TNF) drugs for the treatment of psoriatic arthritis: an indirect comparison meta-analysis [0.03%]
抗肿瘤坏死因子(TNF)药物治疗银屑病关节炎的间接比较meta分析研究
Kristian Thorlund,Eric Druyts,J Antonio Aviña-Zubieta et al.
Kristian Thorlund et al.
Objective: To evaluate the comparative effectiveness of available tumor necrosis factor-α inhibitors (anti-TNFs) for the management of psoriatic arthritis (PsA) in patients with an inadequate response to disease-modifyin...
Systematic review and network meta-analysis of combination and monotherapy treatments in disease-modifying antirheumatic drug-experienced patients with rheumatoid arthritis: analysis of American College of Rheumatology criteria scores 20, 50, and 70 [0.03%]
改善病情抗风湿药治疗失败的类风湿关节炎患者联合治疗和单药治疗的系统评价和网状Meta分析：美国风湿病学会缓解标准20、50、70评分分析
Michelle E Orme,Katherine S Macgilchrist,Stephen Mitchell et al.
Michelle E Orme et al.
Background: Biologic disease-modifying antirheumatic drugs (bDMARDs) extend the treatment choices for rheumatoid arthritis patients with suboptimal response or intolerance to conventional DMARDs. The objective of this sys...
Limited cross-reactivity of mouse monoclonal antibodies against Dengue virus capsid protein among four serotypes [0.03%]
抗登革病毒壳蛋白单克隆抗体的交叉反应性有限性研究
Megumi Noda,Promsin Masrinoul,Chaweewan Punkum et al.
Megumi Noda et al.
Background: Dengue illness is one of the important mosquito-borne viral diseases in tropical and subtropical regions. Four serotypes of dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4) are classified in the Flavivirus ge...
Potential role of (124)I-girentuximab in the presurgical diagnosis of clear-cell renal cell cancer [0.03%]
124I-吉伦图昔单抗在透明细胞肾细胞癌术前诊断中的潜在作用
Marc C Smaldone,David Yt Chen,Jian Q Yu et al.
Marc C Smaldone et al.
Renal cell carcinoma (RCC) is a biologically heterogeneous disease, with many small renal masses (SRMs) exhibiting an indolent natural history, while others progress more rapidly to become life-threatening. Existing multiphase contrast-enha...
Belatacept for prevention of acute rejection in adult patients who have had a kidney transplant: an update [0.03%]
贝拉西普在预防肾移植受者的急性排斥反应中的作用：更新后的系统综述和meta分析
David Wojciechowski,Flavio Vincenti
David Wojciechowski
In June 2011, the US Food and Drug Administration approved belatacept for the prophylaxis of organ rejection in adult kidney transplant recipients. This review discusses the use of belatacept for the prevention of acute rejection as part of...
Serena Trapasso,Eugenia Allegra
Serena Trapasso
In recent years, many studies have shown that some types of tumors are characterized by the presence of cells with stem-like characteristics, called cancer stem cells (CSCs). These are considered cells that initiate the tumor and are probab...
Marino Paroli
Marino Paroli
Vasculitis syndromes are relative rare conditions but can cause significant mortality and morbidity if not treated adequately. Recent advances in immunosuppressant therapy have radically changed the course of these diseases. However, the st...
Treatment of experienced and naïve patients with hepatitis C: focus on telaprevir [0.03%]
特拉匹韦治疗丙型肝炎经治和初治患者：特刊关注特拉匹韦
Roberta D&#x;Ambrosio,Alessio Aghemo,Massimo Colombo
Roberta D&#x;Ambrosio
Telaprevir (TVR) is an orally available protease inhibitor of the hepatitis C virus that in association with pegylated interferon and ribavirin (PR) was shown to improve the rates of sustained virological response and potentially reduce tre...
Introduction to the use of belatacept: a fusion protein for the prevention of posttransplant kidney rejection [0.03%]
Belatacept的使用入门：一种预防移植肾排斥反应的融合蛋白
Giovanbattista Ippoliti,Andrea Maria D&#x;Armini,Marco Lucioni et al.
Giovanbattista Ippoliti et al.
The development of new immunosuppressive drugs for kidney transplantation resulted both in better short-term outcomes and in decreased metabolic, cardiovascular, and nephrotoxicity risk. Belatacept belongs to a new class of immunosuppressiv...