Preliminary In Vivo Evaluation of a Hybrid Armored Vascular Graft Combining Electrospinning and Additive Manufacturing Techniques [0.03%]
结合静电纺丝和增材制造技术的杂化血管移植物的体内初步评估研究
Cristiano Spadaccio,Francesco Nappi,Federico De Marco et al.
Cristiano Spadaccio et al.
In this study, we tested in vivo effectiveness of a previously developed poly-l-lactide/poly-ε-caprolactone armored vascular graft releasing heparin. This bioprosthesis was designed in order to overcome the main drawbacks of tissue-enginee...
Screening Analogs of β-OG Pocket Binder as Fusion Inhibitor of Dengue Virus 2 [0.03%]
筛选登革热病毒2型融合抑制剂β-OG结合袋类类似物
Usman Sf Tambunan,Hilyatuz Zahroh,Arli A Parikesit et al.
Usman Sf Tambunan et al.
Dengue is an infectious disease caused by dengue virus (DENV) and transmitted between human hosts by mosquitoes. Recently, Indonesia was listed as a country with the highest cases of dengue by the Association of Southeast Asian Nations. The...
Management of Diabetes Associated with Nephrotic Syndrome: Therapeutic Potential of Dapagliflozin for Protracted Volume Retention [0.03%]
与肾病综合征相关糖尿病的管理：达格列净治疗持续性容量潴留的潜在疗效
Toshimi Imai,Tetsu Akimoto,Chiharu Ito et al.
Toshimi Imai et al.
A 48-year-old female was admitted to our hospital presenting with a chief complaint of progressive swelling because of diabetic nephrotic syndrome. Dapagliflozin seemed to play a role in accelerating the patient's urinary sodium excretion a...
Case Reports
Drug target insights. 2015 Nov 11:9:29-31. DOI:10.4137/DTI.S31710 2015
Basal Plasma Levels of Copeptin are Elevated in Inactive Inflammatory Bowel Disease after Bowel Resection [0.03%]
回肠造口术后的炎症性肠病患者血浆copeptin水平升高
Bodil Ohlsson,Olle Melander
Bodil Ohlsson
Evidence of interactions between the enteric nervous system, neuropeptides, and the immune system is growing. The aim of this study was to examine basal plasma levels of a variety of peptide precursors in patients with inflammatory bowel di...
Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division [0.03%]
药用植物：一种针对细胞分裂的化合物潜在来源
Ihsan N Zulkipli,Sheba R David,Rajan Rajabalaya et al.
Ihsan N Zulkipli et al.
Modern medicinal plant drug discovery has provided pharmacologically active compounds targeted against a multitude of conditions and diseases, such as infection, inflammation, and cancer. To date, natural products from medicinal plants rema...
7-NI and ODQ Disturbs Memory in the Elevated Plus Maze, Morris Water Maze, and Radial Arm Maze Tests in Mice [0.03%]
7-尼和ODQ干扰小鼠增强型十字迷宫、莫里斯水迷宫及空间八臂迷宫试验中的记忆形成
Oguz Mutlu,Furuzan Akar,Ipek Komsuoglu Celikyurt et al.
Oguz Mutlu et al.
Nitric oxide (NO) is an atypical neurotransmitter that causes changes in cognition. Nitric oxide synthase (NOS) and guanylate cyclase (GC) inhibitors have been shown to exert some effects on cognition in previous studies; however, the findi...
Genome-wide Analysis of Mycoplasma hominis for the Identification of Putative Therapeutic Targets [0.03%]
MGH基因组的全基因组分析以鉴定潜在治疗靶点
Md Masud Parvege,Monzilur Rahman,Mohammad Shahnoor Hossain
Md Masud Parvege
Ever increasing propensity of antibiotic resistance among pathogenic bacteria raises the demand for the development of novel therapeutic agents to control this grave problem. Advances in the field of bioinformatics, genomics, and proteomics...
The Expression of Serum Antibodies Against Gonadotropin-releasing Hormone (GnRH1), Progonadoliberin-2, Luteinizing Hormone (LH), and Related Receptors in Patients with Gastrointestinal Dysfunction or Diabetes Mellitus [0.03%]
胃肠功能障碍或糖尿病患者促性腺激素释放素(GnRH1)、促生殖素-2、黄体生成素(LH)及其相关受体的血清抗体表达式样研究
Bodil Roth,Kerstin Berntorp,Bodil Ohlsson
Bodil Roth
Gonadotropin-releasing hormone (GnRH) 1 and 2 and luteinizing hormone (LH) receptors have been described in the gastrointestinal tract. We have previously demonstrated antibodies in serum against GnRH1 in patients with gastrointestinal dysf...
Febuxostat for hyperuricemia in patients with advanced chronic kidney disease [0.03%]
慢性肾病晚期患者痛风及高尿酸血症的新疗法：febuxostat治疗
Tetsu Akimoto,Yoshiyuki Morishita,Chiharu Ito et al.
Tetsu Akimoto et al.
Febuxostat is a nonpurine xanthine oxidase (XO) inhibitor, which recently received marketing approval. However, information regarding the experience with this agent among advanced chronic kidney disease (CKD) patients is limited. In the cur...
Molecular and Kinetic Characterization of Babesia microti Gray Strain Lactate Dehydrogenase as a Potential Drug Target [0.03%]
巴贝斯虫灰株乳酸脱氢酶的分子和动力学表征作为潜在药物靶点的研究
Patrick Vudriko,Tatsunori Masatani,Shinuo Cao et al.
Patrick Vudriko et al.
Babesia microti is an emerging zoonotic protozoan organism that causes "malaria-like" symptoms that can be fatal in immunocompromised people. Owing to lack of specific therapeutic regiment against the disease, we cloned and characterized B....