Antioxidant potential of a new macrocyclic bisbibenzyl and other compounds from Combretum molle: in vitro and docking analyses [0.03%]
Combretum molle中新macrocycle双bibenzyl及其他化合物的抗氧化潜力:体外及对接分析
Angele Fanta,Gaetan Bayiha Ba Njock,Amadou Dawe et al.
Angele Fanta et al.
Introduction: Free radicals are key contributors to several diseases, including cancer, inflammation, pain, and neurodegenerative disorders such as Alzheimer's disease. Due to the limitations and adverse effects of synthe...
Ravulizumab in treatment-naïve patients with atypical hemolytic uremic syndrome: a real-world case series [0.03%]
拉珠利单抗在初治典型溶血性尿毒综合征患者中的疗效:真实世界个案系列研究报告
Sorrentino Livia Maria,Candida Iacuzzo,Raffaela Sciri et al.
Sorrentino Livia Maria et al.
Introduction: Atypical hemolytic uremic syndrome (aHUS) is a potentially life-threatening condition associated with poor clinical outcomes if not treated adequately. Eculizumab has become the standard of care, whereas rav...
Co-occurrence of genes encoding carbapenem resistance and aminoglycoside resistance in clinical isolates of Enterobacterales [0.03%]
临床分离的肠杆菌目中碳青霉烯耐药和氨基糖苷耐药基因的共存
Shradha Smriti,Gaurav Verma,Sujit Pradhan et al.
Shradha Smriti et al.
Introduction: This study aimed to detect the co-occurrence of carbapenem resistance genes along with aminoglycoside-modifying enzyme (AME) genes in clinical Enterobacterales isolates to understand the distribution of mult...
The Bushenhuoxue formula improves prothrombotic state in recurrent spontaneous abortion: network pharmacology and experimental validation [0.03%]
补血活血汤改善复发性流产促凝状态的网络药理学及实验验证
Xuan Yang,Shulan Su,Lijing Liu et al.
Xuan Yang et al.
Introduction: Bushenhuoxue formula is a traditional Chinese medicine formula with relatively safe clinical effects, but its mechanism in recurrent spontaneous abortion (RSA) is still unclear. Our present study used Networ...
Integrated in vitro, microarray, and network pharmacology analysis reveals the multi-target anti-diabetic potential of Vigna unguiculata [0.03%]
集成体外实验,微阵列和网络药理学分析揭示了伏击花扁袖李的多种抗糖尿病潜力
Haseeba Sardar,Fatima Noor,Syed Muhammad Mukarram Shah et al.
Haseeba Sardar et al.
Introduction: Diabetes mellitus (DM), particularly type 2 DM (T2DM), is a chronic metabolic disorder requiring novel therapeutic approaches as the available therapies are not meeting the current challenges. This study inv...
Integrative in silico and Petra/Osiris/Molinspiration (POM) analysis of baicalein: identification of therapeutically relevant pharmacophores against keloid pathology [0.03%]
黄芩素的综合计算机及Petra/Osiris/Molinspiration(POM)分析:鉴定针对瘢痕病理的治疗相关药效团
Abhay P Mishra,Anothai Tangsumranjit,Manisha Nigam et al.
Abhay P Mishra et al.
Introduction: Keloid scars are a kind of skin disorder in which the scar grows beyond the boundaries of the original wound. Baicalein, a flavonoid, may treat keloids by targeting fibrosis, inflammation, and possible viral...
Anti-Inflammatory and Regenerative Properties of Herbal Extracts: Wound Management in Equine Models [0.03%]
中药提取物的抗炎和再生性能:马科动物模型伤口处理研究
Gustavo W Fehrenbach,Katie Sheils,Mariana J Silva et al.
Gustavo W Fehrenbach et al.
Introduction: Wound management presents significant challenges, requiring effective treatments. Herbal extracts have been traditionally used to support healing due to their anti-inflammatory, antimicrobial, and cell-regen...
Establishment and evaluation of a naked-eye diagnostic assay for tuberculosis utilizing reverse isothermal amplification-assisted CRISPR-Cas in resource-limited settings [0.03%]
基于反向等温扩增技术的CRISPR-Cas在资源受限地区结核分枝杆菌检测中的应用及评价
Ankush Kaushik,Jitendra Singh,Zeeshan Fatima et al.
Ankush Kaushik et al.
Introduction: The current scenario of tuberculosis (TB) caused by Mycobacterium tuberculosis (MTB) has presented an almost insurmountable challenge to hospitals with high patient numbers. Delayed diagnosis of TB is a majo...
Withania somnifera root extract (LongeFera™) confers beneficial effects on health and lifespan of the model worm Caenorhabditis legans [0.03%]
Withania somnifera根提取物(LongeFeraTM)对模式线虫Caenorhabditis elegans的健康和寿命有益
Nidhi Thakkar,Gemini Gajera,Dilip Mehta et al.
Nidhi Thakkar et al.
Background: Withania somnifera is among the most widely prescribed medicinal plants in traditional Indian medicine. Hydroalcoholic extract of the roots of this plant was investigated for its effects on the overall health ...
Exploring the in vitro anti-diabetic potential and in silico studies of 2, 3 and 2, 6-dichloroIndolinone [0.03%]
2,3和2,6-二氯吲哚啉酮的体外抗糖尿病潜力及计算机研究探索
Abdur Rauf,Waqas Alam,Momin Khan et al.
Abdur Rauf et al.
Introduction: Adequate hyperglycemic control is still a huge challenge with the clinically used therapeutics. New, more effective anti-diabetic agents are on the top list of drug discovery projects. ...