Crhistian-Mario Oblitas,Francisco Galeano-Valle,Laura Vela-De La Cruz et al.
Crhistian-Mario Oblitas et al.
A 43-year-old man with a history of severe extrinsic allergic asthma treated with once-monthly omalizumab (600 mg) for the last 15 months. He presented to the emergency room with a 2-week history of right lower limb pain and chest pleuritic...
Vernakalant in Atrial Fibrillation: A Relatively New Weapon in the Armamentarium Against an Old Enemy [0.03%]
Vernakalant在房颤治疗中的地位：抵抗旧敌的新式武器
Antoine Kossaify
Antoine Kossaify
Atrial fibrillation is the most common sustained cardiac arrhythmia, and its prevalence is increasing with age; also it is associated with significant morbidity and mortality. Rhythm control is advised in recent-onset atrial fibrillation, a...
A Comprehensive Review of Pegvaliase, an Enzyme Substitution Therapy for the Treatment of Phenylketonuria [0.03%]
佩加利塞酶替代疗法治疗苯酮尿症的全面回顾
Tasmina Hydery,Valerie Azzopardi Coppenrath
Tasmina Hydery
Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of a phenylalanine-metabolizing enzyme indicated to reduce blood phenylalanine concentrations, pegvaliase injection. ...
DRESS Syndrome and Daclizumab Failure-Were Potentially Dangerous Signs Missed in Clinical Trials? [0.03%]
直流单抗治疗失败及Dress综合征-临床试验过程中是否忽视了危险信号？
Jagannadha Avasarala
Jagannadha Avasarala
The US Food and Drug Administration (FDA) approved Zinbryta, an interleukin-2 receptor blocking antibody (daclizumab; Biogen and AbbVie) for the treatment of adults with relapsing forms of multiple sclerosis (MS) in May, 2016. It was also a...
Valacyclovir Neurotoxicity and Nephrotoxicity in an Elderly Patient Complicated by Hyponatremia [0.03%]
缬更昔洛韦致老年患者神经毒性和肾毒性并发低钠血症１例报告
Takuya Murakami,Tetsu Akimoto,Mari Okada et al.
Takuya Murakami et al.
A 66-year-old women with no history of renal disease was admitted due to a coma and acute kidney injury with a serum creatinine level of 7.44 mg/dL which were ascribed to valacyclovir neurotoxicity and nephrotoxicity, respectively. She had ...
Anti-CD20 Cell Therapies in Multiple Sclerosis-A Fixed Dosing Schedule for Ocrelizumab is Overkill [0.03%]
针对多发性硬化症的抗CD20细胞治疗-Ocrelizumab固定剂量方案过度用力了
Jagannadha Avasarala
Jagannadha Avasarala
Anti-CD 20 therapies have found significant uses in multiple sclerosis (MS). Based singularly on the accumulated evidence with the use of rituximab (RTX; Rituxan, Genentech, and Biogen) in neuroimmunological diseases, ocrelizumab (OCR; Ocre...
Ethanol Extract of Blighia sapida Stem Bark Show Remarkable Prophylactic Activity in Experimental Plasmodium berghei-Infected Mice [0.03%]
Blighia sapida茎皮的乙醇提取物对实验性Plasmodium berghei感染小鼠具有显著预防作用
Olayinka O Otegbade,Johnson A Ojo,Dolapo I Adefokun et al.
Olayinka O Otegbade et al.
This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)-resistant Plasmodium berghei (ANKA strain)-infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inocu...
Modification of S-Adenosyl-l-Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation [0.03%]
基于分子对接和分子动力学模拟的S-腺苷蛋氨酸类似物抑制登革病毒NS5甲基转移酶的研究
Usman Sumo Friend Tambunan,Mochammad Arfin Fardiansyah Nasution,Fauziah Azhima et al.
Usman Sumo Friend Tambunan et al.
Dengue fever is still a major threat worldwide, approximately threatening two-fifths of the world's population in tropical and subtropical countries. Nonstructural protein 5 (NS5) methyltransferase enzyme plays a vital role in the process o...
CURRENT DEVELOPMENTS IN DRUG ELUTING DEVICES: Introductory Editorial: Drug-Eluting Stents or Drug-Eluting Grafts? Insights from Proteomic Analysis [0.03%]
药物缓释装置的最新进展：简介：药物缓释支架还是药物缓释移植物？来自蛋白质组学分析的观点
Cristiano Spadaccio,Francesco Nappi,Nawwar Al-Attar et al.
Cristiano Spadaccio et al.
Immunoinformatics Approach in Designing Epitope-based Vaccine Against Meningitis-inducing Bacteria (Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae Type b) [0.03%]
免疫信息学在设计流行性脑膜炎诱导细菌（肺炎链球菌、脑膜炎奈瑟氏球菌和b型流感嗜血杆菌）的基于表位的疫苗中的作用
Hilyatuz Zahroh,Ahmad Ma&#x;rup,Usman Sumo Friend Tambunan et al.
Hilyatuz Zahroh et al.
Meningitis infection is one of the major threats during Hajj season in Mecca. Meningitis vaccines are available, but their uses are limited in some countries due to religious reasons. Furthermore, they only give protection to certain serogr...