Valacyclovir Neurotoxicity and Nephrotoxicity in an Elderly Patient Complicated by Hyponatremia [0.03%]
缬更昔洛韦致老年患者神经毒性和肾毒性并发低钠血症１例报告
Takuya Murakami,Tetsu Akimoto,Mari Okada et al.
Takuya Murakami et al.
A 66-year-old women with no history of renal disease was admitted due to a coma and acute kidney injury with a serum creatinine level of 7.44 mg/dL which were ascribed to valacyclovir neurotoxicity and nephrotoxicity, respectively. She had ...
Anti-CD20 Cell Therapies in Multiple Sclerosis-A Fixed Dosing Schedule for Ocrelizumab is Overkill [0.03%]
针对多发性硬化症的抗CD20细胞治疗-Ocrelizumab固定剂量方案过度用力了
Jagannadha Avasarala
Jagannadha Avasarala
Anti-CD 20 therapies have found significant uses in multiple sclerosis (MS). Based singularly on the accumulated evidence with the use of rituximab (RTX; Rituxan, Genentech, and Biogen) in neuroimmunological diseases, ocrelizumab (OCR; Ocre...
Ethanol Extract of Blighia sapida Stem Bark Show Remarkable Prophylactic Activity in Experimental Plasmodium berghei-Infected Mice [0.03%]
Blighia sapida茎皮的乙醇提取物对实验性Plasmodium berghei感染小鼠具有显著预防作用
Olayinka O Otegbade,Johnson A Ojo,Dolapo I Adefokun et al.
Olayinka O Otegbade et al.
This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)-resistant Plasmodium berghei (ANKA strain)-infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inocu...
Modification of S-Adenosyl-l-Homocysteine as Inhibitor of Nonstructural Protein 5 Methyltransferase Dengue Virus Through Molecular Docking and Molecular Dynamics Simulation [0.03%]
基于分子对接和分子动力学模拟的S-腺苷蛋氨酸类似物抑制登革病毒NS5甲基转移酶的研究
Usman Sumo Friend Tambunan,Mochammad Arfin Fardiansyah Nasution,Fauziah Azhima et al.
Usman Sumo Friend Tambunan et al.
Dengue fever is still a major threat worldwide, approximately threatening two-fifths of the world's population in tropical and subtropical countries. Nonstructural protein 5 (NS5) methyltransferase enzyme plays a vital role in the process o...
CURRENT DEVELOPMENTS IN DRUG ELUTING DEVICES: Introductory Editorial: Drug-Eluting Stents or Drug-Eluting Grafts? Insights from Proteomic Analysis [0.03%]
药物缓释装置的最新进展：简介：药物缓释支架还是药物缓释移植物？来自蛋白质组学分析的观点
Cristiano Spadaccio,Francesco Nappi,Nawwar Al-Attar et al.
Cristiano Spadaccio et al.
Immunoinformatics Approach in Designing Epitope-based Vaccine Against Meningitis-inducing Bacteria (Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae Type b) [0.03%]
免疫信息学在设计流行性脑膜炎诱导细菌（肺炎链球菌、脑膜炎奈瑟氏球菌和b型流感嗜血杆菌）的基于表位的疫苗中的作用
Hilyatuz Zahroh,Ahmad Ma&#x;rup,Usman Sumo Friend Tambunan et al.
Hilyatuz Zahroh et al.
Meningitis infection is one of the major threats during Hajj season in Mecca. Meningitis vaccines are available, but their uses are limited in some countries due to religious reasons. Furthermore, they only give protection to certain serogr...
Effects and Safety of Linagliptin as an Add-on Therapy in Advanced-Stage Diabetic Nephropathy Patients Taking Renin-Angiotensin-Aldosterone System Blockers [0.03%]
利格列汀在使用肾素-血管紧张素-醛固酮系统阻滞剂的糖尿病肾病综合症晚期患者中的疗效及安全性研究
Yuichiro Ueda,Hiroki Ishii,Taisuke Kitano et al.
Yuichiro Ueda et al.
Background: We investigated the effects and safety of linagliptin as an add-on therapy in patients with advanced-stage diabetic nephropathy (DMN) taking renin-angiotensin-aldosterone system (RAAS) blockers. ...
Gentamicin-Impregnated Collagen Sponge: Effectiveness in Preventing Sternal Wound Infection in High-Risk Cardiac Surgery [0.03%]
含金霉素胶原海绵防治高危冠脉手术患者胸骨伤口感染的有效性研究
Filippo Rapetto,Vito D Bruno,Gustavo Guida et al.
Filippo Rapetto et al.
Sternal wound infections represent one of the most frequent complications after cardiac surgery and are associated with high postoperative mortality. Several preventive methods have been introduced, and recently, gentamicin-impregnated coll...
Paraskevi Fragkou,Maria Souli,Maria Theochari et al.
Paraskevi Fragkou et al.
Until recently, chemotherapy for metastatic melanoma had disappointing results. The identification of immune checkpoints such as CTLA-4 and PD-1/PD-L1 has led to the development of an array of monoclonal antibodies (Mabs). These immunologic...
Case Reports
Drug target insights. 2016 May 22:10:9-12. DOI:10.4137/DTI.S31565 2016
Brain Histamine N-Methyltransferase As a Possible Target of Treatment for Methamphetamine Overdose [0.03%]
脑组胺N-甲基转移酶可能是冰毒中毒的治疗靶点
Junichi Kitanaka,Nobue Kitanaka,F Scott Hall et al.
Junichi Kitanaka et al.
Stereotypical behaviors induced by methamphetamine (METH) overdose are one of the overt symptoms of METH abuse, which can be easily assessed in animal models. Currently, there is no successful treatment for METH overdose. There is increasin...