Bodil Roth,Jonas Manjer,Bodil Ohlsson
Bodil Roth
Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been desc...
Impact of hepatocyte growth factor on skeletal myoblast transplantation late after myocardial infarction [0.03%]
肝细胞生长因子对心梗后骨骼肌前体细胞移植影响的研究
Stacy B OBlenes,Audrey W Li,Chris Bowen et al.
Stacy B OBlenes et al.
In clinical studies, skeletal myoblast (SKMB) transplantation late after myocardial infarction (MI) has minimal impact on left ventricular (LV) function. This may be related to our previous observation that the extent of SKMB engraftment is...
Antibodies against gonadotropin-releasing hormone in patients with posterior laryngitis [0.03%]
后喉炎患者的促性腺激素释放激素抗体
Hillevi Pendleton,Ragnar Alm,Gunilla Nordin Fredrikson et al.
Hillevi Pendleton et al.
Patients with functional gastrointestinal disorders express antibodies against gonadotropin-releasing hormone (GnRH) in serum. One common cause of posterior laryngitis (PL) is extra-esophageal reflux, but a functional etiology has also been...
Drug Target Exploitable Structural Features of Adenylyl Cyclase Activity in Schistosoma mansoni [0.03%]
活性腺苷酸环化酶在曼氏血吸虫中的药物靶标可利用的结构特征
Andreas N Mbah,Henri L Kamga,Omotayo R Awofolu et al.
Andreas N Mbah et al.
The draft genome sequence of the parasitic flatworm Schistosoma mansoni (S. mansoni), a cause of schistosomiasis, encodes a predicted guanosine triphosphate (GTP) binding protein tagged Smp_059340.1. Smp_059340.1 is predicted to be a member...
17AAG Treatment Accelerates Doxorubicin Induced Cellular Senescence: Hsp90 Interferes with Enforced Senescence of Tumor Cells [0.03%]
17AAG治疗加速多柔比星诱导的细胞衰老:Hsp90干扰肿瘤细胞强制性衰老
Upasana Sarangi,Khande Rao Paithankar,Jonnala Ujwal Kumar et al.
Upasana Sarangi et al.
Hsp90 chaperone has been identified as an attractive pharmacological target to combat cancer. However, some metastatic tumors either fail to respond to Hsp90 inhibition or show recovery necessitating irreversible therapeutic strategies. In ...
Expression of Luteinizing Hormone Receptor in the Gastrointestinal Tract in Patients with and without Dysmotility [0.03%]
动力型和非动力型肠易激综合征患者胃肠组织黄体生成素受体的表达差异研究
Oskar Hammar,Béla Veress,Agneta Montgomery et al.
Oskar Hammar et al.
Leuprolide is a gonadotropin-releasing hormone (GnRH) analog which has been shown to reduce symptoms in patients with irritable bowel syndrome (IBS) and chronic intestinal pseudo-obstruction (CIPO). The mechanism is not known, but one hypot...
Resveratrol Targeting of Carcinogen-Induced Brain Endothelial Cell Inflammation Biomarkers MMP-9 and COX-2 is Sirt1-Independent [0.03%]
白藜蘆醇通過SIRT1非依賴方式降低腫瘤诱发因子誘導的腦血管內皮細胞炎症標志物MMP-9和COX-2
Borhane Annabi,Simon Lord-Dufour,Amélie Vézina et al.
Borhane Annabi et al.
The occurrence of a functional relationship between the release of metalloproteinases (MMPs) and the expression of cyclooxygenase (COX)-2, two inducible pro-inflammatory biomarkers with important pro-angiogenic effects, has recently been in...
Predictors of Virologic Failure in HIV/AIDS Patients Treated with Highly Active Antiretroviral Therapy in Brasília, Brazil During 2002-2008 [0.03%]
2002年至2008年巴西首都布拉西利亚HIV/AIDs患者使用高效抗逆转录病毒治疗失败的预测因素
Edson José Monteiro Bello,Amabel Fernandes Correia,José Ricardo Pio Marins et al.
Edson José Monteiro Bello et al.
Little data exists concerning the efficacy of the antiretroviral therapy in the Federal District in Brazil, therefore in order to improve HIV/AIDS patients' therapy and to pinpoint hot spots in the treatment, this research work was conducte...
Repercussion of Mitochondria Deformity Induced by Anti-Hsp90 Drug 17AAG in Human Tumor Cells [0.03%]
抗癌药物17AAG诱导的人肿瘤细胞线粒体形态异常及其影响机制研究
Chaturvedi Vishal,Jonnala Ujwal Kumar,Cherukuvada Veera Brahmendra Swamy et al.
Chaturvedi Vishal et al.
Inhibiting Hsp90 chaperone roles using 17AAG induces cytostasis or apoptosis in tumor cells through destabilization of several mutated cancer promoting proteins. Although mitochondria are central in deciding the fate of cells, 17AAG induced...
The effect of valproic Acid on mesenchymal pluripotent cell proliferation and differentiation in extracellular matrices [0.03%]
细胞外基质中丙戊酸对间充质多能细胞增殖及分化的影响
Yuji Hatakeyama,Junko Hatakeyama,Atsushi Takahashi et al.
Yuji Hatakeyama et al.
Valproic acid (2-n-propylpentanoic acid, VPA) is a widely used antiepileptic and anticonvulsant drug. Previous studies have reported that VPA effects osteogenesis in vivo and in vitro, yet it remains unclear whether VPA promotes cell differ...