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期刊名:Drug target insights

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ISSN:1177-3928

e-ISSN:1177-3928

IF/分区:3.7/Q2

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共收录本刊相关文章索引139条
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Bodil Roth,Jonas Manjer,Bodil Ohlsson Bodil Roth
Microscopic colitis (MC) is a disease with intestinal mucosal inflammation causing diarrhea, affecting predominantly middle-aged women. The etiology is unknown, but increased prevalence of autoimmune diseases in these patients has been desc...
Stacy B O&#x;Blenes,Audrey W Li,Chris Bowen et al. Stacy B O&#x;Blenes et al.
In clinical studies, skeletal myoblast (SKMB) transplantation late after myocardial infarction (MI) has minimal impact on left ventricular (LV) function. This may be related to our previous observation that the extent of SKMB engraftment is...
Hillevi Pendleton,Ragnar Alm,Gunilla Nordin Fredrikson et al. Hillevi Pendleton et al.
Patients with functional gastrointestinal disorders express antibodies against gonadotropin-releasing hormone (GnRH) in serum. One common cause of posterior laryngitis (PL) is extra-esophageal reflux, but a functional etiology has also been...
Andreas N Mbah,Henri L Kamga,Omotayo R Awofolu et al. Andreas N Mbah et al.
The draft genome sequence of the parasitic flatworm Schistosoma mansoni (S. mansoni), a cause of schistosomiasis, encodes a predicted guanosine triphosphate (GTP) binding protein tagged Smp_059340.1. Smp_059340.1 is predicted to be a member...
Upasana Sarangi,Khande Rao Paithankar,Jonnala Ujwal Kumar et al. Upasana Sarangi et al.
Hsp90 chaperone has been identified as an attractive pharmacological target to combat cancer. However, some metastatic tumors either fail to respond to Hsp90 inhibition or show recovery necessitating irreversible therapeutic strategies. In ...
Oskar Hammar,Béla Veress,Agneta Montgomery et al. Oskar Hammar et al.
Leuprolide is a gonadotropin-releasing hormone (GnRH) analog which has been shown to reduce symptoms in patients with irritable bowel syndrome (IBS) and chronic intestinal pseudo-obstruction (CIPO). The mechanism is not known, but one hypot...
Borhane Annabi,Simon Lord-Dufour,Amélie Vézina et al. Borhane Annabi et al.
The occurrence of a functional relationship between the release of metalloproteinases (MMPs) and the expression of cyclooxygenase (COX)-2, two inducible pro-inflammatory biomarkers with important pro-angiogenic effects, has recently been in...
Edson José Monteiro Bello,Amabel Fernandes Correia,José Ricardo Pio Marins et al. Edson José Monteiro Bello et al.
Little data exists concerning the efficacy of the antiretroviral therapy in the Federal District in Brazil, therefore in order to improve HIV/AIDS patients' therapy and to pinpoint hot spots in the treatment, this research work was conducte...
Chaturvedi Vishal,Jonnala Ujwal Kumar,Cherukuvada Veera Brahmendra Swamy et al. Chaturvedi Vishal et al.
Inhibiting Hsp90 chaperone roles using 17AAG induces cytostasis or apoptosis in tumor cells through destabilization of several mutated cancer promoting proteins. Although mitochondria are central in deciding the fate of cells, 17AAG induced...
Yuji Hatakeyama,Junko Hatakeyama,Atsushi Takahashi et al. Yuji Hatakeyama et al.
Valproic acid (2-n-propylpentanoic acid, VPA) is a widely used antiepileptic and anticonvulsant drug. Previous studies have reported that VPA effects osteogenesis in vivo and in vitro, yet it remains unclear whether VPA promotes cell differ...